Submit diagnosis evidence
Submit your transcription-translation model and mutation analysis CER to the unit tracker.
Complete DNA-to-protein packet: transcription-translation model with original and mutated sequences labeled, Thursday CER with sequence-comparison evidence and diagnosis connection, mutation variable and limitations documented, and self-assessment form.
- 1Do thisSubmit your transcription-translation model and mutation analysis CER to the unit tracker.
- 2Use this resource
- 3Submit thisTracker entry: Complete DNA-to-protein packet: transcription-translation model with original and mutated sequences labeled, Thursday CER with sequence-comparison evidence and diagnosis connection, mutation variable and limitations documented, and self-assessment form.
- 4Submit it here
- 1CMSD website. Go to clevelandmetroschools.org and click the Clever button.
- 2Clever. Clever opens. Sign in if it asks.
- 3Microsoft (district) login. Use your district Microsoft account (the one for school).
- 4Schoology. Open Schoology, then your class, then Assignments, and find the file named below.
The file to submit is named: Principles of Biomedical Technology (Principles of Biomedical Science) › Unit 2.2 Decoding a Diagnosis: DNA, chromosomes, genes, proteins, protein synthesis, mutation, inheritance. › Tracker entryOpen Schoology
- CER:
- Claim, Evidence, Reasoning — make a claim, back it with evidence, explain your reasoning.
- SOP:
- Standard Operating Procedure — the exact steps to follow (especially in a lab).
- Tracker:
- Your PLTW progress log where you record completed evidence.
- myPLTW:
- The PLTW course site where you do the online activities — you open it through Schoology.
Minute-by-minute · 80-minute block
💡 Big idea: A complete DNA-to-protein packet traces the molecular chain from a single base change in DNA to a potential clinical diagnosis, demonstrating the power and limits of the central dogma.
- 0:00Project the tracker checklist; walk through each required item
- 0:10Work time: upload transcription-translation model (original and mutated sequences); verify mutation variable is labeled
- 0:28Work time: upload Thursday CER; verify sequence evidence is cited and a diagnosis connection is stated
- 0:45Confirm mutation variable and model limitations are documented
- 0:58Self-assessment form: check each success criterion; flag any item not fully met
- 1:08Course-closing reflection: in one sentence, how does the central dogma connect a genetic mutation to a medical diagnosis?
- • This is the final submission of the decoding-a-diagnosis unit. You are submitting a molecular argument: here is the DNA, here is the protein it makes, here is what the mutation changed, and here is what that change could mean clinically.
- • Before you upload your model: does it show both the original and the mutated sequence? If it only shows the mutated version, a reader cannot evaluate the change.
- • Before you upload your CER: does it cite a specific amino acid change and name the type of mutation? Does it name a real disease or condition as a diagnosis connection?
- • Self-assess against every success criterion. The central dogma is one of the most important concepts in all of biology. Make sure your packet shows you understand it.
- 1Review the tracker checklist for decoding-a-diagnosis deliverables.
- 2Upload your transcription and translation model.
- 3Attach your mutation analysis CER.
- 4Confirm the mutation variable and limitations are documented.
- 5Self-assess against success criteria and flag gaps.
- • I can submit a complete DNA-to-protein packet.
- • I can verify my work against a checklist.
- • A submitted transcription-translation model must show both the original and mutated sequences to be a valid comparison; without both, the change cannot be evaluated.
- • The mutation variable must be identified explicitly: which base position changed, from which nucleotide to which nucleotide.
- • Self-assessment at the end of this unit is also an assessment of your understanding of the central dogma: can you trace each step from DNA to protein to disease?
Your PLTW work today
Unit 2.2 Decoding a Diagnosis: DNA, chromosomes, genes, proteins, protein synthesis, mutation, inheritance. · Submit diagnosis evidence
Day 5 of this lesson. Open this exact section in myPLTW (reached through Schoology), then do the work below.
Do this: Open myPLTW and confirm all Lesson 2.2 Decoding a Diagnosis tasks are marked complete.
All Lesson 2.2 tasks should show as complete in your myPLTW progress view.
Every item from Monday through Thursday should be submitted today before you leave.
Completed myPLTW Lesson 2.2 unit with all tasks marked, plus tracker submission including transcription-translation model, mutation analysis CER, and self-assessment.
All PLTW activities are completed inside the PLTW course environment — this page only gives direction. Submit producibles on Schoology.
Today's PLTW tracker
Check things off as you work, then submit. This tells Mr. Mendoza how you're doing so he can help the class. It does not replace turning in your producible on Schoology.
Use the code Mr. Mendoza gave you, not your name. Saved on this device.
Unit 2.2 Decoding a Diagnosis: DNA, chromosomes, genes, proteins, protein synthesis, mutation, inheritance. · Submit diagnosis evidence
Open myPLTW and confirm all Lesson 2.2 Decoding a Diagnosis tasks are marked complete.
Every item from Monday through Thursday should be submitted today before you leave.
This is how Mr. Mendoza sees the class keeping pace with PLTW. Be honest, it only helps if it is accurate.
🎯 Submit your transcription-translation model and mutation analysis CER to the unit tracker.
- Review the tracker checklist for decoding-a-diagnosis deliverables.
- Upload your transcription and translation model.
- Attach your mutation analysis CER.
- Confirm the mutation variable and limitations are documented.
- Self-assess against success criteria and flag gaps.
Tracker entry: Complete DNA-to-protein packet: transcription-translation model with original and mutated sequences labeled, Thursday CER with sequence-comparison evidence and diagnosis connection, mutation variable and limitations documented, and self-assessment form.
Submit on SchoologyUpload by 11:29 PM for full credit.
| Task | Who |
|---|---|
| Review the tracker checklist for decoding-a-diagnosis deliverables. | _______ |
| Upload your transcription and translation model. | _______ |
| Attach your mutation analysis CER. | _______ |
| Confirm the mutation variable and limitations are documented. | _______ |
| Self-assess against success criteria and flag gaps. | _______ |
Working solo? Put your own name in "Who" for every row.
- I can submit a complete DNA-to-protein packet.
- I can verify my work against a checklist.
Resources & readings
Hand-picked materials for this lesson. Class file items open the document directly; the rest are vetted readings and interactives from other biomedical programs.
Lab & supplies
WebXam practice
Cumulative WebXam review
A quick mixed-review pulling questions from earlier units plus today, so the WebXam material stays fresh.
Where this leads — careers
What today's skills lead to. These are real health-science careers this course builds toward. Tap one to see, on the US Department of Labor's O*NET site, what the job actually involves, what it pays, and how fast it is growing.
What to do if you were absent
Today is individual PLTW work, so do exactly what we did in class, from home: complete the same PLTW target above, then submit your Tracker entry.
Open Schoology (CMSD) and keep goingHow to get there: open the CMSD website, click Clever, sign in with your Microsoft (district) account, then open Schoology from Clever.
Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:
Learn.Genetics (University of Utah): DNA to protein- CompleteEvery required part of the artifact is present, nothing left blank.
- AccurateThe science and the data are correct and match the evidence.
- Scientific reasoningYou explain your claim with evidence and reasoning (CER), not just an answer.
- Professional communicationClear, organized, labeled, and written the way a clinician or scientist would.
- SubmittedTurned in the right way (Schoology for routine work) and confirmed.
Drop your Tue, Oct 20, 2026 · Submit diagnosis evidence here. Use a clear file name (your initials + project). Routine work still goes to Schoology (via the CMSD portal).
Upload a project