Clinical diagnosis team project

Open your materials, follow the steps, then turn in your work.

Student teams synthesize patient data to propose and justify a working diagnosis.

Before lab work: Read the safety rules below and wait for your teacher’s approval. You may read the directions while you wait.

1. Open your materials

Use the materials named in the first step below. Open lesson resources.

2. Start the work

As a team, define the SOP for reviewing a patient chart in a fixed order.

Show all 5 required steps
  1. As a team, define the SOP for reviewing a patient chart in a fixed order.
  2. Identify which variables in the chart are normal and which are out of range.
  3. Combine history, vitals, bloodwork, and genetics into a shared evidence table.
  4. Generate a ranked differential diagnosis and select the most likely candidate.
  5. Assign each member a section of the recommendation and note data limitations.

Lost your place? Lost your place? Confirm your team's fixed chart-review order, then get every out-of-range value into the shared evidence table before you rank the differential.

Check your work before submitting

  • Team produces a ranked differential grounded in the full data set.
  • Each member contributes a documented section and identifies one limitation.

Before lab work: read the safety rules

  • Wear the required PPE, keep the bench clear, handle equipment only as directed, and know where the eyewash, sink, and spill kit are before you start.
  • Human samples and data stay private: label with a code, never a name, and dispose of materials in the correct waste container, then wash your hands.

3. Turn in your work

DueCheck Schoology
Hand in
Shared team evidence table with all four workup components, flagged out-of-range values, and a ranked differential diagnosis with the top candidate selected.
How to submit and name your file

Use the submission route shown on today's today's page.

In Schoology, open your course and the assignment for this lesson. Attach your file, select Submit, and check that it appears in the submission.

PDF upload help

You get two school days for every day you were absent, so this deadline moves with you.

Find this lesson's Schoology assignments

These are existing assignments for your section. Follow the directions in the assignment you are working on; this list does not add new work. Check Schoology for each deadline.

Link will not open? Open Schoology, choose your course and section, and find the title shown above.

How this lesson connects

Keep using what you learned last class: A pedigree feeds parental genotypes into a Punnett square, so a family's history becomes a quantified probability instead of a rough estimate. Today: A team using a shared, ordered evidence table catches blind spots a lone reviewer misses, so combining people and data sources makes the diagnosis more accurate.

Print or open for todayProblem 2.3.1 A New Patient

Check you have the right sheet: the top of it prints today's portal day, Clinical diagnosis team project. The PLTW activity itself is in myPLTW and is not posted here.

Unit 4 extra creditNine items open when we finish Unit 2. Read the cover sheet now so you know what is coming.Cover sheet (6 pages)See all nine
Optional: listen or watch a unit review
Optional unit study notebook
The diagnostic workup: the lab tests and imaging that turn symptoms into a diagnosis.
Open the notebook
Optional review video
Audio overviewVideo overviewMind mapStudy guideFlashcardsQuizData table
Need help? Warm-up, timing, and directions

💡 Big idea: A team using a shared, ordered evidence table catches blind spots a lone reviewer misses, so combining people and data sources makes the diagnosis more accurate.

  1. 0-8 minAssign team roles: chart reviewer, vitals analyst, lab analyst, genetics reader.
  2. 8-15 minAgree on SOP: order in which the team reviews each chart section.
  3. 15-40 minIndependent analysis by role; each member flags normal vs. out-of-range values.
  4. 40-58 minBuild shared evidence table; generate ranked as a group.
  5. 58-70 minSelect most likely candidate; each member drafts their recommendation section.
  6. 70-80 minEach member records one data limitation; team shares aloud before end of period.
Mr. Mendoza's 5-minute intro
  • Today you function as a clinical team, each role matters and each person's section feeds the final recommendation.
  • Real diagnostic teams use structured SOPs so nothing gets reviewed out of order or skipped.
  • Your evidence table is the shared document every team member writes to and reads from.
  • The limitation each person identifies is not optional: it shows the team where the diagnosis is still uncertain.
Know by the end
  • A shared evidence table organizes all workup data so the team can compare findings systematically.
  • A ranked differential lists candidates from most to least likely, with data supporting each rank.
  • Each team member owning a section of the recommendation distributes accountability and reduces blind spots.

PLTW connection and today's work

In myPLTW, open Lesson 2.3 New to the Practice and go to Problem 2.3.1 A New Patient. Work it alongside the patient chart.

Today's stopping point: You took workup notes Tuesday. Today your platform work and evidence table should both be substantially complete.

PLTW activity titles identify the course connection. If your account will not open, use the posted materials for today and tell Mr. Mendoza. Do not mark an online activity complete unless you completed it.

Course connection

  • Problem 2.3.1 A New Patient
Open Problem 2.3.1 A New Patient in myPLTW

Use the turn-in directions at the top of this page. Do not create a second submission unless your teacher asks for one.

Show another explanation or a smaller first step

Need help? Choose a starting point

Run the lab
Run the lab: build the shared evidence table from all four data sources, flag every out-of-range value, generate a ranked differential, pick the top candidate, and assign each member a section with its data limitations noted.
Missed class? Start here
Absent or behind? Catch up async by taking the provided chart, filling the evidence table for just the flagged abnormal values, and writing which single condition they most support and why.

Finish the assigned lab safely before starting extra practice.

Lesson resources: reading, slides, and vocabulary
Socratic teaching slide deck

The deck carries the prior idea forward, lets you inspect an analogy, maps the rule to biology, and ends with the same evidence decision and exit ticket used on this page.

Generated from this lesson's canonical data with a red-team citation check.

Carry forward

A pedigree feeds parental genotypes into a Punnett square, so a family's history becomes a quantified probability instead of a rough estimate.

Daily take-home

A team using a shared, ordered evidence table catches blind spots a lone reviewer misses, so combining people and data sources makes the diagnosis more accurate.

Inspect the analogy

A smoke alarm detects signs of fire but can also react to burnt toast.

  1. What does the alarm detect?
  2. What creates a false alarm?
  3. What evidence is needed before declaring a fire?
Rule

A screening signal changes what to investigate next; it does not automatically prove the cause.

Where it breaks

Biomedical tests have measured performance and biological sampling limits that a household alarm does not capture.

Map the analogy to biology
  • Alarm signal maps to a test result.
  • Burnt toast maps to a .
  • Inspection maps to confirmation or the next test.
Read this first

Driving question: Your team has one full of history, vitals, bloodwork, and genetics. Following a fixed review order, which values are out of range, and what is your ranked differential with the most likely candidate on top?

What you already know: A pedigree feeds parental genotypes into a Punnett square, so a family's history becomes a quantified probability instead of a rough estimate.

New idea: A team using a shared, ordered evidence table catches blind spots a lone reviewer misses, so combining people and data sources makes the diagnosis more accurate.

Visual or model: F1. F1. A lesson illustration or teaching diagram for Clinical diagnosis team project. Use it with E1-E3; it is a model or context image, not experimental or patient data. What to notice: Trace the labeled observation or evidence sequence before choosing an explanation.

  1. Observe or measure the relevant feature in clinical diagnosis team project.
  2. Organize the observation with a stable evidence ID.
  3. Apply this rule: A screening signal changes what to investigate next; it does not automatically prove the cause.
  4. Choose the option the evidence supports and state the limit of the conclusion.

Real biomedical example: Your team has one full of history, vitals, bloodwork, and genetics. Following a fixed review order, which values are out of range, and what is your ranked differential with the most likely candidate on top?

What the evidence supports: E1-E3 and F1 support the daily take-home when the response meets the stated success criteria.

What it cannot prove: The package does not support claims beyond this lesson's or any real patient diagnosis.

Vocabulary:
  • : The ranked list of conditions that could explain a patient's story. The whole game is narrowing it honestly.
  • : Combining findings from many separate sources into one organized conclusion, weighing how strong and consistent the evidence is overall.
  • : A procedure that analyzes a sample of blood, urine, or to provide measurable information that helps diagnose or monitor a condition.
  • : An organized record of a patient's medical history, test results, medications, and care, used by the healthcare team to make decisions.
  • recommendation: A clear, evidence-based suggestion for what action to take, drawn from analyzing data, results, or a patient's situation.

Use it now: Choose one decision option. Cite E1 and E3, then explain how the rule connects the evidence to your choice.

Go further, optional: The source links below are optional enrichment. Every fact required for today's local evidence decision appears in this lesson package.

Evidence set and decision
E1 · Source fact

A classroom clinical recommendation must connect case findings to a plausible mechanism, expected benefit and harm, alternatives, and uncertainty without presenting the composite case as a real diagnosis or prescription.

Limit: The classroom case omits clinical history, examination, validated testing, patient preferences, and professional judgment needed for real care.

E2 · Teaching model

A screening signal changes what to investigate next; it does not automatically prove the cause.

Limit: Biomedical tests have measured performance and biological sampling limits that a household alarm does not capture.

E3 · Task criterion

Team produces a ranked differential grounded in the full data set.

Limit: E3 defines the classroom product or success criterion. It is not independent scientific evidence and cannot justify a clinical or causal claim.

PLTW-PBT-2026-11-10 · Simulated classroom evidence scenario

Your role: biomedical investigator

Decision: Your team must decide what the evidence from clinical diagnosis team project supports before submitting the labeled and result claim named on today's page.

  • Name the confirmatory test and run it before recommending treatment, because the current data still allows a second condition.
  • Write a claim naming one specific condition, backed by history, a lab value, and one more data type.
  • Claim that fatigue and high blood sugar together are the diagnosis, since those findings are what the patient's data shows.

Response: State one choice, cite at least two evidence IDs, explain the rule that connects them, and add one limitation. Submit it as the labeled and result claim.

Claim ceiling: Today's evidence supports a classroom claim about clinical diagnosis team project. It cannot prove causation, diagnose a real patient, or justify action outside this room.

Composite case file · PLTW-PBT-2026-11-10

Reason for review: Your team must decide what the evidence from clinical diagnosis team project supports before submitting the labeled and result claim named on today's page.

Context: Clinical diagnosis improves when multiple people synthesize multiple data sources, because a shared, organized process catches the blind spots any single reviewer would miss.

Timeline:
  • T1: As a team, define the SOP for reviewing a in a fixed order.
  • T2: Identify which variables in the chart are normal and which are out of range.
  • T3: Combine history, vitals, bloodwork, and genetics into a shared evidence table.
  • T4: Generate a ranked and select the most likely candidate.
  • T5: Assign each member a section of the recommendation and note data limitations.
Evidence records:
  • E1: A classroom clinical recommendation must connect case findings to a plausible mechanism, expected benefit and harm, alternatives, and uncertainty without presenting the composite case as a real diagnosis or prescription.
  • E2: A screening signal changes what to investigate next; it does not automatically prove the cause.
  • E3: Team produces a ranked differential grounded in the full data set.

Measurements: Use only the measurements, units, graph, or counts supplied in today's task. No additional patient measurement is implied.

Figure finding: Teaching diagram for Clinical diagnosis team project. Trace the labeled observation or evidence sequence before choosing an explanation. This is a teaching model, not patient or experimental data.

Uncertainty: This is a composite classroom scenario. Missing history, measurements, or confirmation tests remain unknown and limit the conclusion.

Math moment
Formula or setup

Mean = sum of values / number of values. Median = middle ordered value. Range = maximum - minimum.

Worked parallel example

For 2, 4, 4, and 10: mean = 20 / 4 = 5, median = 4, and range = 10 - 2 = 8.

Units and reasonableness

Mean, median, and range keep the measurement unit. Order the values before finding the median.

Try it with today's data

Calculate the requested summary for today's supplied values, then write what it reveals and what it hides.

Watch the trap

Students often think Students think dividing the work means each teammate looks at only their own section and the diagnosis is just stapled together at the end.. The trap: That is a trap because a diagnosis comes from combining sections, not isolating them. The evidence table exists so every teammate sees how history, vitals, labs, and genetics line up together; splitting ownership of the writeup is about accountability, not about reviewing the data in silos.

Worked example · a parallel case (guides, does not reveal)
Shared team evidence table
Completes: A team-built evidence table combining all four workup components with out-of-range values flagged and a ranked differential diagnosis with the top candidate selected.

Team evidence table for Patient A:

  • History: frequent thirst, frequent urination, family history of diabetes. Flag: relevant risk.
  • Vital signs: BP 122/80 mmHg (slightly high), pulse 78 bpm (normal).
  • Bloodwork: fasting glucose 145 mg/dL (OUT OF RANGE, normal 70 to 99), cholesterol 190 mg/dL (normal).
  • Genetic screen: no single-gene flag.

Ranked differential: (1) Type 2 diabetes (top candidate, supported by high glucose plus classic symptoms and family history), (2) prediabetes, (3) stress-related transient hyperglycemia. Top candidate selected: Type 2 diabetes.

Each member owns one section; one stated limitation: only one glucose draw, so a repeat fasting test is needed.

ComponentFindingIn/Out of range
Historythirst, urination, family hxrisk present
VitalsBP 122/80, pulse 78BP slightly high
Bloodworkglucose 145 mg/dLOUT (normal 70-99)
Geneticsno single-gene flagnormal
Team evidence table listing each workup component, its finding, and whether it is in or out of range, with glucose flagged out of range.
Why this matters

This model shows the level of evidence and organization needed to complete: A team-built evidence table combining all four workup components with out-of-range values flagged and a ranked differential diagnosis with the top candidate selected.

Build yours step by step
  1. Name the variables and include units.
  2. Enter observations without changing the raw values.
  3. Check labels, calculations, and patterns before interpreting the data.
Change it for a new task

Keep the structure. Replace the question, facts, measurements, and evidence. Then recheck units, vocabulary, and whether the conclusion goes beyond the evidence.

Also due today: One member turns in the evidence table on Schoology with all team names on the document.

See the full worked example
Portal terms
CER:
Claim, Evidence, Reasoning: make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure, the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities. Find it in Clever with your Microsoft sign-in, right next to Schoology.
This unit's vocabulary

Tap the speaker to hear a term. Add two of these to your notebook glossary with a definition and an example in your own words.

Build your vocabulary · optional, for extra credit

Pick just 2 or 3 words from today and make them yours: write what each one means in your own words, name the context clue or evidence that helped, then give one example from what you actually did in Clinical diagnosis team project. Try your own words first; the glossary is there if you get stuck. This is voluntary and counts as extra credit, so keep it short.

differential diagnosis
evidence synthesis
laboratory test
patient chart
recommendation

Saved on this device. Show Mr. Mendoza or add these to your notebook glossary to claim the extra credit.

Resources & readings

Hand-picked readings and interactives for this lesson, from authoritative open organizations and PLTW's own public course outline.

Practice: try a question, then check your answer

Claim ceiling for this check: Today's evidence supports a classroom claim about clinical diagnosis team project. It cannot prove causation, diagnose a real patient, or justify action outside this room.

Quick self-check · commit, then reveal

Your evidence table shows an out-of-range value that supports two of your differential candidates equally. What should your team do before ranking one above the other?

How sure are you?

Write an answer and pick a confidence to unlock the key.

Cumulative WebXam review · flash practice

Fast retrieval with instant answers, not the commit-then-reveal check above. Try each from memory first: write what you remember about the earlier units, then check yourself here.

Tap an answer to check it · nothing is recorded or graded
[Review: Decoding a Diagnosis: from DNA to protein] A bacterial transformation produces zero colonies even though the protocol was followed. Which is the most likely cause?
[Review: Genetic Risk: karyotypes, pedigrees, and diagnosing from mixed evidence] A genetic test reports a result without listing its false-positive rate. Why does that limit an evidence-based conclusion?
[Review: Genetic Risk: karyotypes, pedigrees, and diagnosing from mixed evidence] A genetic test reports a result without listing its false-positive rate. Why does that limit an evidence-based conclusion?
A patient with suspected bacterial infection has a complete blood count. Which result most supports infection?
Missed class or ready for more?
🔬 Pre-lab simulation

Run this before you touch the bench. It is built from the real lab procedure, so the decisions you make here are the ones you will make with the equipment in your hands.

The Bellyache: Close It Honestly
Open the simulation →
Lab · prepare, conduct, complete
1Prepare
Pre-lab pass · clear all six to go to the bench
0/6

I can name the procedure's purpose and the evidence I will record. I can state today's specific hazards and the control for each. If this deck does not name them, I ask Mr. Mendoza before I touch anything. My data table is ready before materials are handled.

Finish the checklist before you handle any material.

Safety · specific to today's hazards
  • Wear the required PPE, keep the bench clear, handle equipment only as directed, and know where the eyewash, sink, and spill kit are before you start.
  • Human samples and data stay private: label with a code, never a name, and dispose of materials in the correct waste container, then wash your hands.
Review Lab Safety (rules, PPE, SDS, emergencies) and check your contract + test
2Conduct (Argument-Driven Inquiry)
  1. 1Before materials are handled, identify the purpose, variables or comparison, controls, measurement units, and stop-work condition.
  2. 2As a team, define the SOP for reviewing a patient chart in a fixed order.
  3. 3Identify which variables in the chart are normal and which are out of range.
  4. 4Combine history, vitals, bloodwork, and genetics into a shared evidence table.
  5. 5Generate a ranked differential diagnosis and select the most likely candidate.
  6. 6Assign each member a section of the recommendation and note data limitations.
  7. 7Record each result in the prepared table before interpreting it. Mark missing, repeated, or invalid results truthfully.
  8. 8Complete the named cleanup and waste route, remove PPE safely, wash hands when required, and confirm the station is ready for the next group.
Prepare this data table before materials are handled
Trial or sample IDIndependent conditionMeasured result with unitsObservation before interpretationQuality-control note
     
     
     
3Complete
Argue from your evidence, then compare what you predicted to what happened. Error analysis names a specific method limit, never "human error".
You predicted

Before the procedure, predict the result and cite the rule behind the prediction.

What actually happened

After the procedure, compare the result with the prediction and name one limitation or source of uncertainty.

Your lab report is graded on the rubric below, with extra weight on error analysis and method.
Where this leads: careers
What to do if you were absent
Today was a project: do this instead

Group clinical-diagnosis project: teams assemble the new-patient evidence table, rank a , and draft a shared recommendation for the next session.

MedlinePlus: Lab Tests

Use the submission route shown on today's today's page.

If MR. MENDOZA is absent

Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:

NIH MedlinePlus Lab Tests
How this is graded
For: Data table: Shared team evidence table with all four workup components, flagged out-of-range values, and a ranked differential diagnosis with the top candidate selected.
  • Complete
    Every required part of the artifact is present, nothing left blank.
  • Accurate
    The science and the data are correct and match the evidence.
  • Scientific reasoning
    You explain your claim with evidence and reasoning (CER), not just an answer.
  • Professional communication
    Clear, organized, labeled, and written the way a clinician or scientist would.
  • Submitted
    Go to Schoology to turn this in. Submit one PDF. Put your first and last name in the document header. Name the file: FirstName LastName - Assignment Title - YYYY-MM-DD.pdf. If you cannot get in, see Mr. Mendoza. Do not skip the work.
  • Error analysis and method · counts double
    Name a specific limit of the method and how it moved your result, and compare what you predicted to what happened. "Human error" does not count; say what about the procedure or instrument caused it.