Fri, Sep 11, 2026Fall (Semester 1) · Week 3Day 14 of 7580-min block

Analyze tox results

Today's target

Interpret biomolecule and toxicology data with a CER and assess method limitations.

Due today · CER Required

CER stating which biomolecules are present in each unknown, using Wednesday's data table as evidence and citing comparison to positive and negative controls in the reasoning.

Your 4 steps today
  1. 1
    Do this
    Interpret biomolecule and toxicology data with a CER and assess method limitations.
  2. 2
  3. 3
    Submit this
    CER: CER stating which biomolecules are present in each unknown, using Wednesday's data table as evidence and citing comparison to positive and negative controls in the reasoning.
  4. 4
    Submit it here
    1. 1CMSD website. Go to clevelandmetroschools.org and click the Clever button.
    2. 2Clever. Clever opens. Sign in if it asks.
    3. 3Microsoft (district) login. Use your district Microsoft account (the one for school).
    4. 4Schoology. Open Schoology, then your class, then Assignments, and find the file named below.
    The file to submit is named: Principles of Biomedical Technology (Principles of Biomedical Science) › Unit 1.1 to 1.2: Experimental design in evidence testing; transition to autopsy evidence and biomolecules. › CER
    Open Schoology
Were you absent? Jump to the make-up plan
Where this fits
Tested on (Ohio WebXam)
Principles and Practice of Biomedical Technology · 072110
PLTW lesson
PBS · Analyze tox results
WebXam domain
Biotechnology Research and Experiments
Evidence to produce
CER
Explore

Read to prepare for today

Quick glossary
CER:
Claim, Evidence, Reasoning — make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure — the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities — you open it through Schoology.
Learn first

Minute-by-minute · 80-minute block

💡 Big idea: Interpreting test results requires comparing unknowns against controls, not trusting a color change in isolation.

  1. 0:00Return Wednesday data tables; identify any groups whose negative control showed a color change (class discussion of what that means)
  2. 0:12Walk through interpretation logic: positive control matched, negative control flat, unknown matches positive = positive result
  3. 0:25Students interpret their unknown results, noting biomolecules present or absent for each sample
  4. 0:40Analyze dilution series: describe the dose-response trend in words; identify threshold if visible
  5. 0:55CER writing: claim (which biomolecules present), evidence (data table), reasoning (comparison to controls)
  6. 1:10List two false-positive sources and one limitation of indicator tests; preview Friday submission
Mr. Mendoza's 5-minute intro
  • Your data from Wednesday is only half the story. Today we interpret it. And interpreting data means comparing your unknowns to your controls, not just reading a color.
  • If your negative control changed color too, that is a problem. It tells you something went wrong with your technique or your reagent, and your unknown results may not be valid.
  • We will also look at your dilution series and describe the dose-response relationship. In toxicology, this relationship is the foundation of every safety limit ever set, from drinking-water standards to medication dosing.
  • Your CER today is your scientific argument about what biomolecules are in each unknown. Evidence comes from the data table; reasoning comes from the comparison to controls.
Do this, step by step
  1. 1Compare unknown-sample results to your control results.
  2. 2Write a CER: which biomolecules are present in each unknown?
  3. 3Analyze the dose-response trend in your toxicology dilution data.
  4. 4Identify two variables that could produce a false positive.
  5. 5State one limitation of indicator tests for forensic conclusions.
You'll be able to
  • I can interpret indicator results against controls.
  • I can describe a dose-response trend and its limits.
Know by the end
  • An unknown result is interpreted as positive only if it matches the positive control and differs from the negative control.
  • A dose-response relationship shows that as concentration increases, the measured effect increases; a threshold is the concentration below which no measurable effect appears.
  • Common sources of false positives in indicator tests include cross-contamination between tubes, using the wrong reagent concentration, and interference from pigments in the sample.
📺 Tutor me: NIH MedlinePlus: Toxicology
Do the work

Your PLTW work today

Open this PLTW section today

Unit 1.1 to 1.2: Experimental design in evidence testing; transition to autopsy evidence and biomolecules. · Analyze tox results

Day 4 of this lesson. Open this exact section in myPLTW (reached through Schoology), then do the work below.

Do this: In myPLTW, complete the Lesson 1.1 Investigating the Scene evidence-testing analysis section by entering your interpreted results and the dose-response description.

Complete

Mark the Lesson 1.1 analysis section complete in myPLTW.

How far to get

You collected data Wednesday. By the end of today your CER and dose-response description should both be done.

Upload as evidence

Completed myPLTW Lesson 1.1 analysis entry and written CER with controls-based interpretation.

All PLTW activities are completed inside the PLTW course environment — this page only gives direction. Submit producibles on Schoology.

The plan

Today's PLTW tracker

Check things off as you work, then submit. This tells Mr. Mendoza how you're doing so he can help the class. It does not replace turning in your producible on Schoology.

Use the code Mr. Mendoza gave you, not your name. Saved on this device.

Unit 1.1 to 1.2: Experimental design in evidence testing; transition to autopsy evidence and biomolecules.Day 4 of this projectSee the full week plan
Today's PLTW target

Unit 1.1 to 1.2: Experimental design in evidence testing; transition to autopsy evidence and biomolecules. · Analyze tox results

In myPLTW, complete the Lesson 1.1 Investigating the Scene evidence-testing analysis section by entering your interpreted results and the dose-response description.

You collected data Wednesday. By the end of today your CER and dose-response description should both be done.

This is how Mr. Mendoza sees the class keeping pace with PLTW. Be honest, it only helps if it is accurate.

1 · What you do today

🎯 Interpret biomolecule and toxicology data with a CER and assess method limitations.

  • Compare unknown-sample results to your control results.
  • Write a CER: which biomolecules are present in each unknown?
  • Analyze the dose-response trend in your toxicology dilution data.
  • Identify two variables that could produce a false positive.
  • State one limitation of indicator tests for forensic conclusions.
2 · Turn in today

CER: CER stating which biomolecules are present in each unknown, using Wednesday's data table as evidence and citing comparison to positive and negative controls in the reasoning.

Submit on Schoology

Upload by 11:29 PM for full credit.

3 · Who's doing what (team)
TaskWho
Compare unknown-sample results to your control results._______
Write a CER: which biomolecules are present in each unknown?_______
Analyze the dose-response trend in your toxicology dilution data._______
Identify two variables that could produce a false positive._______
State one limitation of indicator tests for forensic conclusions._______

Working solo? Put your own name in "Who" for every row.

4 · Words I can use correctly
5 · I'm successful today when I can…
  • I can interpret indicator results against controls.
  • I can describe a dose-response trend and its limits.
6 · Reflection & next steps
Where are you today?0/7 checked
Pick your period and code first.
Explore

Resources & readings

Hand-picked materials for this lesson. Class file items open the document directly; the rest are vetted readings and interactives from other biomedical programs.

Words

This unit's vocabulary

biomoleculemacromoleculetoxicology/tok-sih-KOL-uh-jee/tissueautopsycause of deathmanner of death

Tap the speaker to hear a term. Weekly vocabulary task: add two of these terms to your notebook glossary with a definition and an example in your own words.

Check yourself

WebXam practice

Tap an answer to check it · nothing is recorded or graded
You are measuring the rate that catalase breaks down hydrogen peroxide. What is the dependent variable?
You test how diet impacts joint inflammation by giving mice regular versus special diets. What is the independent variable?
In the arthritis diet experiment, what serves as the control?
A researcher measures the zone of inhibition created by different mouthwashes. What is the dependent variable?
Check yourself

Cumulative WebXam review

A quick mixed-review pulling questions from earlier units plus today, so the WebXam material stays fresh.

Tap an answer to check it · nothing is recorded or graded
[Review: Course Launch: your lab notebook, PPE, and the language of evidence] Your analytical balance performance verification shows the standard's mass reads too low. What is the next step?
[Review: Investigating the Scene: documenting evidence like a forensic scientist] A researcher records a mistake in a notebook. What is the legally and scientifically correct way to handle it?
You are measuring the rate that catalase breaks down hydrogen peroxide. What is the dependent variable?
Explore

Where this leads — careers

Safety net

What to do if you were absent

If YOU are absent

Today is individual PLTW work, so do exactly what we did in class, from home: complete the same PLTW target above, then submit your CER.

Open Schoology (CMSD) and keep going

How to get there: open the CMSD website, click Clever, sign in with your Microsoft (district) account, then open Schoology from Clever.

If MR. MENDOZA is absent

Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:

Khan Academy: macromolecules
How this is graded
For: CER — CER stating which biomolecules are present in each unknown, using Wednesday's data table as evidence and citing comparison to positive and negative controls in the reasoning.
  • Complete
    Every required part of the artifact is present, nothing left blank.
  • Accurate
    The science and the data are correct and match the evidence.
  • Scientific reasoning
    You explain your claim with evidence and reasoning (CER), not just an answer.
  • Professional communication
    Clear, organized, labeled, and written the way a clinician or scientist would.
  • Submitted
    Turned in the right way (Schoology for routine work) and confirmed.
Submission Zone

Drop your Fri, Sep 11, 2026 · Analyze tox results here. Use a clear file name (your initials + project). Routine work still goes to Schoology (via the CMSD portal).

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