Mon, Aug 31, 2026Fall (Semester 1) · Week 2Day 5 of 6080-min blockTight fit

Bioethics of evidence

Essential question: When should we trust scientific evidence, and who is responsible when it is wrong?Enduring understanding: Evidence is only as reliable as the method and the person behind it, so a credible claim always shows its reasoning, not just its result.

Do now

Debate whether forensic and biomedical evidence should ever be trusted blindly, and defend a claim with reasons.

DueTonight, 11:29 PM
Hand in
Written CER (3-5 sentences) arguing one side of the trust-the-evidence debate with a claim, one piece of evidence, and one reasoning sentence.
Where
Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

You get two school days for every day you were absent, so this deadline moves with you.

Where you are · this course
Unit Course Launch: PLTW access, lab notebook, PPE/SDS, evidence handling, variables, controls, graphing, descriptive statistics. Bioethics of evidence ▸ Day 1
Day 5 of 60 this semester55 left before WebXam
🧬 Where you are · PLTW
Principles of Biomedical ScienceUnit 1: Medical Investigations ▸ Lesson 1.1 Investigating the Scene"Activity 1.1.1 A Sketchy Scene", "Activity 1.1.2 Reliable Witnesses"
Activity names previewed from public PLTW district curriculum maps for the updated PBS. Mr. Mendoza will confirm the exact numbers in myPLTW once the course shell opens.
Today's driving question

A lab result once put an innocent person in prison, then turned out to be wrong. Whose fault is that: the machine, the analyst, or the system that trusted it without asking?

Today you'll be able to

Debate whether and biomedical evidence should ever be trusted blindly, and defend a claim with reasons.

You've got it when
  • I can state a claim and back it with a reason.
  • I can explain why a method affects whether evidence is trustworthy.
Due today · CER RequiredWritten CER (3-5 sentences) arguing one side of the trust-the-evidence debate with a claim, one piece of evidence, and one reasoning sentence.
Do-Now · start these with your notes closed
  1. Can a lab test give a wrong answer? Give one way it could.
  2. If it does, who do you think is responsible?
Do this · step by step
numbered so we can always find our place
  1. 1Read the Philosophy-for-Kids prompt: Can a lab result be wrong, and who is responsible when it is?
  2. 2List two reasons a measurement could mislead an investigator or doctor.
  3. 3Pick a side: evidence is objective truth vs. evidence is only as good as its method.
  4. 4Argue your position aloud in your small group using one reason and one example.
  5. 5Post a short written CER: claim, one piece of evidence, one sentence of reasoning.
Interrupted or lost? If you lost your place, reread the prompt and your last sentence, then finish your CER: state your claim, cite your evidence, and explain your reasoning.
The story

What did this day actually feel like?

WebXam pretest and goal setting

We took the WebXam pretest today, which is the state exam we sit in the spring, given to us cold in week one. I did not do well and neither did anyone else, which was the point. He said the pretest is not a grade, it is a baseline, and in December we compare.

Then we set a goal and wrote down how we would get there. Mine is fifteen minutes of review a night using the question side of my Cornell notes. He said the students who do badly on the WebXam are almost never the ones who cannot understand it, they are the ones who met the content once in September and never went back.

Turned in: WebXam practice → recorded in Class Records

Fiction. There is no such student. The lessons, labs and dates are the real planned course; the student, the classmates and the conversations are invented.

The comic

The same day, drawn.

Drawing, panel 7: Bioethics of evidence.

First real Monday. John Carroll was not here yet, so it was just us and him. Forensic labs have sent innocent people to prison on evidence everyone trusted.

CLASSMATE

A person loads the sample. A person labels it. The machine only answers the question a human asked.

Panel 7Bioethics of evidence · 2026-08-31
Read week 1, 6 panels

Fiction. There is no such student. The lessons, labs and dates are the real planned course; the student, the classmates and the conversations are invented.

🛠 Get unstuck · pick your level

Need a running start
New to CER? Fill in the frame: I claim ___ because the evidence shows ___, which means ___.
On track
Write a 3-5 sentence CER arguing one side of the trust-the-evidence debate.
Stuck? Get unstuck
Stuck on reasoning? Ask why your evidence proves your claim, and write exactly that sentence.
Push me further
Argue the side you disagree with, and note which of your reasons is hardest to counter.

🔑 Today's words · 5

safetyPPESDSvariablecontrol
+3 more in the word bank

Tap a word in the lesson for a plain meaning and one example. Recycled into next week's Do-Now.

Today's study notebook
Lab safety, SDS reading, PPE, and keeping a proper science notebook.
Open the notebook
Watch first: today's 1-minute intro
Audio overviewVideo overviewMind mapStudy guideFlashcardsQuizData table
CER · EvidenceThinking like a scientist · Part 2 of 4

What counts as evidence, and where to find it

What makes evidence strong, and where do you find evidence you can trust?

Evidence is the data and observations you use to back up a claim. In science that means measurements, experimental results, images, and records, not “my friend said” or “I saw it once.”

Strong evidence is relevant (it actually bears on the claim), sufficient (there is enough of it), and reliable (it was collected carefully and others could repeat it). One data point is rarely enough; a pattern across many is far stronger.

Where you find it matters. Prefer primary sources and reputable ones: peer-reviewed studies, government and health agencies (CDC, NIH, NHGRI), and your own lab data. When you find a source online, do not trust it on looks. Check who is behind it and what better sources say.

Strong evidence is
  • Relevant: it directly supports (or tests) the claim.
  • Sufficient: there is enough of it, not a single lucky data point.
  • Reliable: collected carefully, and others could reproduce it.
  • Sourced: you can say where it came from and why that source is trustworthy.
Quick source check (SIFT)
  • Stop. Investigate the source: who made this and why?
  • Find better coverage: what do other reputable sources say?
  • Trace claims and quotes back to the original.
Do this today

Find two pieces of evidence for a claim in this unit, one from your lab/class data and one from a reputable source. Note why each source can be trusted.

Where this fits
Tested on (Ohio WebXam)
Principles and Practice of Biomedical Technology · 072110
PLTW lesson
PBS · Lesson 1.1 Investigating the Scene
WebXam domain
Biotechnology Research and Experiments
Evidence to produce
CER
Lab / skill
OSHA Hazard Communication Standard (SDS format)
Do the work · 80-minute blockfirst 5 min = hook

💡 Big idea: Scientific evidence is only as reliable as the method and person behind it.

  1. 0:00Hook: show a headline where lab evidence was later overturned; brief discussion
  2. 0:08Introduce CER framework (claim, evidence, reasoning) with a class example
  3. 0:18Read the Philosophy-for-Kids prompt silently, annotate, list two reasons evidence could mislead
  4. 0:28Small-group debate: pick a side and argue with one reason and one example
  5. 0:50Individual writing: draft CER on the trust-the-evidence question
  6. 1:10Share out two or three CERs; teacher models strong vs. weak reasoning; wrap-up
Mr. Mendoza's 5-minute intro
  • Welcome to Principles of Biomedical Science. This course asks one big question all year: how do we know what we know about the body, disease, and death?
  • Today we start with philosophy, because before we touch a single piece of equipment, we need to ask: can evidence lie? Can a lab result be wrong?
  • Think about a courtroom. Someone goes to prison because DNA evidence said so. But what if the sample was contaminated? What if the analyst made a mistake?
  • Your job today is to pick a side and defend it. By the end of class you will have written your first CER, which is the writing structure we will use all year.
Know by the end
  • A claim must be supported by evidence and reasoning to be credible.
  • Measurement error, bias, and human judgment all affect whether evidence can be trusted.
  • CER (Claim-Evidence-Reasoning) is the framework scientists use to defend conclusions.
Open this PLTW section today

Unit Course Launch: PLTW access, lab notebook, PPE/SDS, evidence handling, variables, controls, graphing, descriptive statistics. · Bioethics of evidence

Day 1 of this lesson. Open this exact section in myPLTW (find it in Clever, Microsoft sign-in), then do the work below.

Do this: Log in to myPLTW and open the Principles of Biomedical Science course. Navigate to the course launch unit and read the introductory overview so you know what to expect from Unit 1.

Complete

Mark the course-launch overview task complete in your myPLTW progress tracker.

How far to get

This is Day 1 of the course. You have no prior lessons to finish. By the end of today you should have logged in, read the overview, and written your first CER.

Upload as evidence

Screenshot of your myPLTW progress showing the launch overview task marked complete, plus your posted CER from today.

The official PLTW activity stays inside myPLTW. If myPLTW will not open, use F1 and E1-E3 on this page to complete today's local evidence decision, then make up the official activity when access returns. Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

Today's PLTW tracker · fill in and submit

Check things off as you work, then submit. This tells Mr. Mendoza how you're doing so he can help the class. It does not replace turning in your producible through the submission route shown below.

Use the code Mr. Mendoza gave you, not your name. Saved on this device.

Unit Course Launch: PLTW access, lab notebook, PPE/SDS, evidence handling, variables, controls, graphing, descriptive statistics.Day 1 of this projectSee the full week plan
Today's PLTW target

Unit Course Launch: PLTW access, lab notebook, PPE/SDS, evidence handling, variables, controls, graphing, descriptive statistics. · Bioethics of evidence

Log in to myPLTW and open the Principles of Biomedical Science course. Navigate to the course launch unit and read the introductory overview so you know what to expect from Unit 1.

This is Day 1 of the course. You have no prior lessons to finish. By the end of today you should have logged in, read the overview, and written your first CER.

This is how Mr. Mendoza sees the class keeping pace with PLTW. Be honest, it only helps if it is accurate.

1 · What you do today

🎯 Debate whether and biomedical evidence should ever be trusted blindly, and defend a claim with reasons.

  • Read the Philosophy-for-Kids prompt: Can a lab result be wrong, and who is responsible when it is?
  • List two reasons a measurement could mislead an investigator or doctor.
  • Pick a side: evidence is objective truth vs. evidence is only as good as its method.
  • Argue your position aloud in your small group using one reason and one example.
  • Post a short written CER: claim, one piece of evidence, one sentence of reasoning.
2 · What you turn in

CER: Written CER (3-5 sentences) arguing one side of the trust-the-evidence debate with a claim, one piece of evidence, and one reasoning sentence.

Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not. Use the checklist just below and upload by 11:29 PM for full credit. Absent with an excused absence? You get two school days for every day you were absent, so this deadline moves with you.

3 · Who's doing what (team)
TaskWho
Read the Philosophy-for-Kids prompt: Can a lab result be wrong, and who is responsible when it is?_______
List two reasons a measurement could mislead an investigator or doctor._______
Pick a side: evidence is objective truth vs. evidence is only as good as its method._______
Argue your position aloud in your small group using one reason and one example._______
Post a short written CER: claim, one piece of evidence, one sentence of reasoning._______

Working solo? Put your own name in "Who" for every row.

4 · Words I can use correctly
5 · I'm successful today when I can…
  • I can state a claim and back it with a reason.
  • I can explain why a method affects whether evidence is trustworthy.
6 · Reflection & next steps
Where are you today?0/7 checked
Pick your period and code first.
Your 4 steps today
  1. 1
    Do this
    Debate whether forensic and biomedical evidence should ever be trusted blindly, and defend a claim with reasons.
  2. 2
  3. 3
    Submit this
    CER: Written CER (3-5 sentences) arguing one side of the trust-the-evidence debate with a claim, one piece of evidence, and one reasoning sentence.
  4. 4
    Submit it here
    1. 1Open the drop folder.
    2. 2Sign in with your district Microsoft account, not a personal one.
    3. 3Upload the file, named Lastname_Firstname__Assignment Title.
    4. 4Your own upload panel says Uploaded with a green check: that is your receipt.
    Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not. Principles of Biomedical Technology (Principles of Biomedical Science) › Unit Course Launch: PLTW access, lab notebook, PPE/SDS, evidence handling, variables, controls, graphing, descriptive statistics. › CER
    Open the drop folder
Were you absent? Jump to the make-up plan
Learn it · deck, reading, and vocabulary
Socratic teaching slide deck

The deck carries the prior idea forward, lets you inspect an analogy, maps the rule to biology, and ends with the same evidence decision and exit ticket used on this page.

Generated from this lesson's canonical data with a red-team citation check.

Carry forward

We earn lab privileges by proving we are safe, and we get credit by submitting clear evidence of our work.

Daily take-home

Scientific evidence is only as reliable as the method and person behind it.

Inspect the analogy

A detective board holds observations, possible explanations, and one next question.

  1. Which notes are direct observations?
  2. Which notes are explanations?
  3. What new evidence would separate the explanations?
Rule

Keep observations separate from explanations, then collect the evidence that can distinguish the options.

Where it breaks

Biomedical investigations use controlled procedures and validated measurements, not intuition alone.

Map the analogy to biology
  • Board notes map to E1-E3.
  • Possible explanations map to the decision options.
  • The next question maps to the evidence-based action.
Read this first

Driving question: A lab result once put an innocent person in prison, then turned out to be wrong. Whose fault is that: the machine, the analyst, or the system that trusted it without asking?

What you already know: We earn lab privileges by proving we are safe, and we get credit by submitting clear evidence of our work.

New idea: Scientific evidence is only as reliable as the method and person behind it.

Visual or model: F1. F1. A lesson illustration or teaching diagram for Bioethics of evidence. Use it with E1-E3; it is a model or context image, not experimental or patient data. What to notice: Trace the labeled observation or evidence sequence before choosing an explanation.

  1. Observe or measure the relevant feature in Bioethics of evidence.
  2. Organize the observation with a stable evidence ID.
  3. Apply this rule: Keep observations separate from explanations, then collect the evidence that can distinguish the options.
  4. Choose the option the evidence supports and state the limit of the conclusion.

Real biomedical example: A lab result once put an innocent person in prison, then turned out to be wrong. Whose fault is that: the machine, the analyst, or the system that trusted it without asking?

What the evidence supports: E1-E3 and F1 support the daily take-home when the response meets the stated success criteria.

What it cannot prove: The package does not support claims beyond this lesson's or any real patient diagnosis.

Vocabulary:
  • : Practices and precautions that protect people from harm, such as wearing protective equipment and handling hazards correctly in a lab or clinic.
  • PPE: Personal protective equipment, the gear like gloves, goggles, lab coats, and masks worn to shield the body from chemical, biological, or physical hazards.
  • SDS: A data sheet: a standardized document listing a chemical's hazards, safe handling steps, and emergency measures for anyone using it.
  • variable: Any factor in an experiment that can change or be changed, including what you test, what you measure, and what you hold steady.
  • control: The comparison condition that isolates the effect of the variable being tested by keeping everything else the same.
  • evidence: The facts, data, and cases that carry your claim. Opinions are free; evidence costs homework.
  • : The documented record of who handled a piece of evidence, when, and where, proving it was never lost, swapped, or tampered with.
  • : Numbers and graphs, such as the mean, median, and range, that summarize and describe a set of data without drawing wider conclusions.

Use it now: Choose one decision option. Cite E1 and E3, then explain how the rule connects the evidence to your choice.

Go further, optional: The source links below are optional enrichment. Every fact required for today's local evidence decision appears in this lesson package.

Evidence set and decision
E1 · Observation

A claim must be supported by evidence and reasoning to be credible.

Limit: E1 supplies context or an observation; it does not by itself establish the explanation.

E2 · Mechanism

Scientific evidence is only as reliable as the method and person behind it.

Limit: E2 is a teaching statement or comparison and must be checked against the task evidence.

E3 · Result

I can state a claim and back it with a reason.

Limit: E3 supports only the result or product criterion named here; it cannot justify a broader clinical or causal claim.

PLTW-PBT-2026-08-31 · Simulated classroom evidence scenario

Your role: biomedical investigator

Decision: Your team must decide what the evidence from Bioethics of evidence supports before submitting the claim-evidence-reasoning response named on the lesson page.

  • Choose the strongest supported explanation.
  • Choose the next evidence to collect.
  • Hold the decision because the evidence is insufficient.

Response: State one choice, cite at least two evidence IDs, explain the rule that connects them, and add one limitation. Submit it as the claim-evidence-reasoning response.

Claim ceiling: The supplied lesson evidence can support an observation, pattern, classroom mechanism, or next-step decision about Bioethics of evidence. It cannot by itself prove causation, establish a real clinical diagnosis, or justify action outside this classroom task.

Composite case file · PLTW-PBT-2026-08-31

Reason for review: Your team must decide what the evidence from Bioethics of evidence supports before submitting the claim-evidence-reasoning response named on the lesson page.

Context: Evidence is only as reliable as the method and the person behind it, so a credible claim always shows its reasoning, not just its result.

Timeline:
  • T1: Read the Philosophy-for-Kids prompt: Can a lab result be wrong, and who is responsible when it is?
  • T2: List two reasons a measurement could mislead an investigator or doctor.
  • T3: Pick a side: evidence is objective truth vs. evidence is only as good as its method.
  • T4: Argue your position aloud in your small group using one reason and one example.
  • T5: Post a short written CER: claim, one piece of evidence, one sentence of reasoning.
Evidence records:
  • E1: A claim must be supported by evidence and reasoning to be credible.
  • E2: Scientific evidence is only as reliable as the method and person behind it.
  • E3: I can state a claim and back it with a reason.

Measurements: Use only the measurements, units, graph, or counts supplied in today's task. No additional patient measurement is implied.

Figure finding: Teaching diagram for Bioethics of evidence. Trace the labeled observation or evidence sequence before choosing an explanation. This is a teaching model, not patient or experimental data.

Uncertainty: This is a composite classroom scenario. Missing history, measurements, or confirmation tests remain unknown and limit the conclusion.

Math moment
Formula or setup

Mean = sum of values / number of values. Median = middle ordered value. Range = maximum - minimum.

Worked parallel example

For 2, 4, 4, and 10: mean = 20 / 4 = 5, median = 4, and range = 10 - 2 = 8.

Units and reasonableness

Mean, median, and range keep the measurement unit. Order the values before finding the median.

Try it with today's data

Calculate the requested summary for today's supplied values, then write what it reveals and what it hides.

Watch the trap

Students often think if it came from a machine or a lab, it must be objective and correct. The trap: measurement error, bias, and human judgment all shape a result, so it came from the lab is not the same as it is right

Worked example · a parallel case (guides, does not reveal)
Worked CER on a parallel case
Completes: A short written claim-evidence-reasoning paragraph on a parallel bioethics-of-evidence case (a consumer fitness tracker's heart-rate reading), modeling the exact CER format and depth students will use for today's own debate without answering today's prompt.

Parallel case for modeling only: Should a doctor rely on the heart-rate reading from a patient's fitness watch to decide on treatment?\n\nClaim: A fitness watch reading should not be used to make a medical decision on its own, because a consumer device is only as reliable as the conditions it was measured under.\nEvidence: Wrist-worn optical heart-rate sensors are known to lose accuracy during vigorous exercise, on darker skin tones, and when the band is loose, sometimes reporting a rate that is off by twenty beats per minute or more compared with a clinical electrocardiogram.\nReasoning: A number on a bright screen feels precise, but the watch estimates heart rate indirectly by shining light through the skin, and that estimate depends on fit, motion, and skin. A clinician who treats the reading as a verified fact skips the question of how it was produced. The device is a starting point, not a diagnosis, so a responsible decision confirms the reading with a validated clinical measurement before acting on it. That is why medical devices are cleared through testing that consumer wearables are not, and why the person reading the number, not just the number, carries responsibility for how it is used.

Why this matters

This model shows the level of evidence and organization needed to complete: A short written claim-evidence-reasoning paragraph on a parallel bioethics-of-evidence case (a consumer fitness tracker's heart-rate reading), modeling the exact CER format and depth students will use for today's own debate without answering today's prompt.

Build yours step by step
  1. Write one defensible claim.
  2. Choose specific evidence that supports the claim.
  3. Explain the scientific rule that connects the evidence to the claim.
Change it for a new task

Keep the structure. Replace the question, facts, measurements, and evidence. Then recheck units, vocabulary, and whether the conclusion goes beyond the evidence.

Also due today: Post your CER to the discussion board or hand in the written copy before you leave.

See the full worked example
Portal terms
CER:
Claim, Evidence, Reasoning: make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure, the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities. Find it in Clever with your Microsoft sign-in, right next to Schoology.
This unit's vocabulary
(Personal Protective Equipment)(Safety Data Sheet)

Tap the speaker to hear a term. Add two of these to your notebook glossary with a definition and an example in your own words.

Build your vocabulary · optional, for extra credit

Pick just 2 or 3 words from today and make them yours: write what each one means in your own words, name the context clue or evidence that helped, then give one example from what you actually did in Bioethics of evidence. Try your own words first; the glossary is there if you get stuck. This is voluntary and counts as extra credit, so keep it short.

safety
PPE
SDS
variable
control
evidence

Saved on this device. Show Mr. Mendoza or add these to your notebook glossary to claim the extra credit.

Resources & readings

Hand-picked readings and interactives for this lesson, from authoritative open organizations and PLTW's own public course outline.

Check yourself · commit, then reveal

Claim ceiling for this check: The supplied lesson evidence can support an observation, pattern, classroom mechanism, or next-step decision about Bioethics of evidence. It cannot by itself prove causation, establish a real clinical diagnosis, or justify action outside this classroom task.

Quick self-check · commit, then reveal

A DNA test says a suspect matches. Name one reason the result could still be wrong, and who would be responsible for catching it.

How sure are you?

Write an answer and pick a confidence to unlock the key.

Cumulative WebXam review · flash practice

Fast retrieval with instant answers, not the commit-then-reveal check above. Try each from memory first: write what you remember about the earlier units, then check yourself here.

Tap an answer to check it · nothing is recorded or graded
[Review: Orientation: how we learn in Principles of Biomedical Science] What is the WebXam?
After using a single-use scalpel in the laboratory, what should you do with it?
Go further and get help
Where this leads: careers
What to do if you were absent
Today was a debate: do this instead

Watch the recorded prompt, then post your written CER (claim-evidence-reasoning) to the discussion board taking one side of the trust-the-evidence debate.

John Carroll Philosophy for Children

Then submit your CER. Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

If MR. MENDOZA is absent

Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:

OSHA Hazard Communication Standard (SDS format)
How this is graded
For: CER: Written CER (3-5 sentences) arguing one side of the trust-the-evidence debate with a claim, one piece of evidence, and one reasoning sentence.
  • Complete
    Every required part of the artifact is present, nothing left blank.
  • Accurate
    The science and the data are correct and match the evidence.
  • Scientific reasoning
    You explain your claim with evidence and reasoning (CER), not just an answer.
  • Professional communication
    Clear, organized, labeled, and written the way a clinician or scientist would.
  • Submitted
    Turned in the right way, on the class site or handed to Mr. Mendoza in class, and confirmed. Not in Schoology: that is where the report-card grade appears later.