Recommendation CER

Open your materials, follow the steps, then turn in your work.

Students write a CER that recommends a diagnosis and next steps from synthesized evidence.

2. Start the work

State a claim naming the most likely diagnosis for the patient.

Show all 5 required steps
  1. State a claim naming the most likely diagnosis for the patient.
  2. Cite specific history, vital, lab, and genetic evidence that support the claim.
  3. Explain reasoning that connects each evidence point to the diagnosis.
  4. Recommend confirmatory tests or referrals to reduce remaining uncertainty.
  5. Name assumptions and limitations that could change the recommendation.

Lost your place? Lost your place? Check that your claim names one specific condition, then work down: cite your history, lab, and one more evidence type, explain each, and end with confirmatory tests and limitations.

Check your work before submitting

  • Write a CER with a clear diagnostic claim and multi-source evidence.
  • Recommend appropriate next steps and state at least one limitation.

3. Turn in your work

DueCheck Schoology
Hand in
CER with a specific diagnostic claim, multi-source evidence from the workup, reasoning linking each evidence point to the claim, a next-steps recommendation, and one stated limitation.
How to submit and name your file

Use the submission route shown on today's today's page.

In Schoology, open your course and the assignment for this lesson. Attach your file, select Submit, and check that it appears in the submission.

PDF upload help

You get two school days for every day you were absent, so this deadline moves with you.

Find this lesson's Schoology assignments

These are existing assignments for your section. Follow the directions in the assignment you are working on; this list does not add new work. Check Schoology for each deadline.

Link will not open? Open Schoology, choose your course and section, and find the title shown above.

How this lesson connects

Keep using what you learned last class: Should vaccination be mandatory? Today: A recommendation earns trust because it names a specific condition, cites multiple data sources, and states its own limits, so a clinician can act on it instead of guessing.

Print or open for todayProblem 2.3.1 A New Patient

Check you have the right sheet: the top of it prints today's portal day, Recommendation CER. The PLTW activity itself is in myPLTW and is not posted here.

Unit 4 extra creditNine items open when we finish Unit 2. Read the cover sheet now so you know what is coming.Cover sheet (6 pages)See all nine
Optional: listen or watch a unit review
Optional unit study notebook
The diagnostic workup: the lab tests and imaging that turn symptoms into a diagnosis.
Open the notebook
Optional review video
Audio overviewVideo overviewMind mapStudy guideFlashcardsQuizData table
Need help? Warm-up, timing, and directions

💡 Big idea: A recommendation earns trust because it names a specific condition, cites multiple data sources, and states its own limits, so a clinician can act on it instead of guessing.

  1. 0-8 minReview Wednesday evidence table; identify the three strongest data points supporting the top diagnosis.
  2. 8-20 minWrite the claim: one sentence naming the most likely diagnosis.
  3. 20-45 minWrite evidence section: cite history, vitals, lab, and genetic data with specific values.
  4. 45-62 minWrite reasoning: connect each evidence point to the diagnostic claim.
  5. 62-72 minAdd next-steps recommendation (confirmatory test or referral) and one limitation.
  6. 72-80 min: check that claim is specific, evidence is multi-source, limitation is stated.
Mr. Mendoza's 5-minute intro
  • Your team built the evidence table yesterday; today you write the individual CER that turns that evidence into a recommendation.
  • Each CER must have a specific diagnosis in the claim, not a general description.
  • Cite at least three data types from the workup: history, vitals, bloodwork, or genetics.
  • The next-steps recommendation is what separates a diagnosis from a plan of care.
Know by the end
  • A diagnostic CER claim must name a specific condition, not just a symptom cluster.
  • Multi-source evidence means citing at least history, one lab value, and one other data type.
  • Recommending confirmatory tests is how clinicians reduce uncertainty without guessing.

PLTW connection and today's work

In myPLTW, go back to Problem 2.3.1 A New Patient in Lesson 2.3 New to the Practice and use it as your writing guide.

Today's stopping point: Platform prompts should be done in the first 15 minutes; the CER is today's main product.

PLTW activity titles identify the course connection. If your account will not open, use the posted materials for today and tell Mr. Mendoza. Do not mark an online activity complete unless you completed it.

Course connection

  • Problem 2.3.1 A New Patient
Open Problem 2.3.1 A New Patient in myPLTW

Use the turn-in directions at the top of this page. Do not create a second submission unless your teacher asks for one.

Show another explanation or a smaller first step

Need help? Choose a starting point

Need a running start
Before writing, make sure your claim names a real condition, not a symptom cluster. Write the single condition your team ranked first yesterday; that sentence is your claim.
On track
Write the full CER: a claim naming the specific diagnosis, evidence from history plus a lab plus one more data type, reasoning linking each point to the diagnosis, recommended confirmatory tests, and stated limitations.
Stuck? Get unstuck
If the CER feels big, build it one brick at a time: write the claim, then paste in three evidence points, then add one sentence of reasoning under each. The structure will carry the rest.
Push me further
Add a second-place diagnosis to your CER and name the exact confirmatory test result that would flip your recommendation from first place to second. That is how clinicians hedge responsibly.
Lesson resources: reading, slides, and vocabulary
Socratic teaching slide deck

The deck carries the prior idea forward, lets you inspect an analogy, maps the rule to biology, and ends with the same evidence decision and exit ticket used on this page.

Generated from this lesson's canonical data with a red-team citation check.

Carry forward

Should vaccination be mandatory?

Daily take-home

A recommendation earns trust because it names a specific condition, cites multiple data sources, and states its own limits, so a clinician can act on it instead of guessing.

Inspect the analogy

A detective board holds observations, possible explanations, and one next question.

  1. Which notes are direct observations?
  2. Which notes are explanations?
  3. What new evidence would separate the explanations?
Rule

Keep observations separate from explanations, then collect the evidence that can distinguish the options.

Where it breaks

Biomedical investigations use controlled procedures and validated measurements, not intuition alone.

Map the analogy to biology
  • Board notes map to the signs, results and measurements you recorded.
  • Possible explanations map to the competing biological causes.
  • The next question maps to the test or observation that would separate them.
Read this first

Driving question: For your patient, can you write a claim that names one specific condition, back it with history plus a lab value plus one more data type, and say out loud what could still prove you wrong?

What you already know: Should vaccination be mandatory?

New idea: A recommendation earns trust because it names a specific condition, cites multiple data sources, and states its own limits, so a clinician can act on it instead of guessing.

Visual or model: F1. F1. A lesson illustration or teaching diagram for Recommendation CER. Use it with E1-E3; it is a model or context image, not experimental or patient data. What to notice: Trace the labeled observation or evidence sequence before choosing an explanation.

  1. Observe or measure the relevant feature in recommendation CER.
  2. Organize the observation with a stable evidence ID.
  3. Apply this rule: Keep observations separate from explanations, then collect the evidence that can distinguish the options.
  4. Choose the option the evidence supports and state the limit of the conclusion.

Real biomedical example: For your patient, can you write a claim that names one specific condition, back it with history plus a lab value plus one more data type, and say out loud what could still prove you wrong?

What the evidence supports: E1-E3 and F1 support the daily take-home when the response meets the stated success criteria.

What it cannot prove: The package does not support claims beyond this lesson's or any real patient diagnosis.

Vocabulary:
  • : The ranked list of conditions that could explain a patient's story. The whole game is narrowing it honestly.
  • : Combining findings from many separate sources into one organized conclusion, weighing how strong and consistent the evidence is overall.
  • : A procedure that analyzes a sample of blood, urine, or to provide measurable information that helps diagnose or monitor a condition.
  • : An organized record of a patient's medical history, test results, medications, and care, used by the healthcare team to make decisions.
  • recommendation: A clear, evidence-based suggestion for what action to take, drawn from analyzing data, results, or a patient's situation.

Use it now: Choose one decision option. Cite E1 and E3, then explain how the rule connects the evidence to your choice.

Go further, optional: The source links below are optional enrichment. Every fact required for today's local evidence decision appears in this lesson package.

Evidence set and decision
E1 · Source fact

A classroom clinical recommendation must connect case findings to a plausible mechanism, expected benefit and harm, alternatives, and uncertainty without presenting the composite case as a real diagnosis or prescription.

Limit: The classroom case omits clinical history, examination, validated testing, patient preferences, and professional judgment needed for real care.

E2 · Teaching model

Keep observations separate from explanations, then collect the evidence that can distinguish the options.

Limit: Biomedical investigations use controlled procedures and validated measurements, not intuition alone.

E3 · Task criterion

Write a CER with a clear diagnostic claim and multi-source evidence.

Limit: E3 defines the classroom product or success criterion. It is not independent scientific evidence and cannot justify a clinical or causal claim.

PLTW-PBT-2026-11-16 · Simulated classroom evidence scenario

Your role: biomedical investigator

Decision: Your team must decide what the evidence from recommendation CER supports before submitting the claim-evidence-reasoning response named on today's page.

  • Name the confirmatory test and run it before recommending treatment, because the current data still allows a second condition.
  • Write a claim naming one specific condition, backed by history, a lab value, and one more data type.
  • Claim that fatigue and high blood sugar together are the diagnosis, since those findings are what the patient's data shows.

Response: State one choice, cite at least two evidence IDs, explain the rule that connects them, and add one limitation. Submit it as the claim-evidence-reasoning response.

Claim ceiling: Today's evidence supports a classroom claim about recommendation CER. It cannot prove causation, diagnose a real patient, or justify action outside this room.

Composite case file · PLTW-PBT-2026-11-16

Reason for review: Your team must decide what the evidence from recommendation CER supports before submitting the claim-evidence-reasoning response named on today's page.

Context: A diagnostic recommendation is only as strong as its evidence, because multi-source support and honestly stated limitations are what separate a defensible claim from a hunch.

Timeline:
  • T1: State a claim naming the most likely diagnosis for the patient.
  • T2: Cite specific history, vital, lab, and genetic evidence that support the claim.
  • T3: Explain reasoning that connects each evidence point to the diagnosis.
  • T4: Recommend confirmatory tests or referrals to reduce remaining uncertainty.
  • T5: Name assumptions and limitations that could change the recommendation.
Evidence records:
  • E1: A classroom clinical recommendation must connect case findings to a plausible mechanism, expected benefit and harm, alternatives, and uncertainty without presenting the composite case as a real diagnosis or prescription.
  • E2: Keep observations separate from explanations, then collect the evidence that can distinguish the options.
  • E3: Write a CER with a clear diagnostic claim and multi-source evidence.

Measurements: No patient measurement is supplied unless it appears explicitly in E1-E3 or F1. Do not invent a value.

Figure finding: Teaching diagram for Recommendation CER. Trace the labeled observation or evidence sequence before choosing an explanation. This is a teaching model, not patient or experimental data.

Uncertainty: This is a composite classroom scenario. Missing history, measurements, or confirmation tests remain unknown and limit the conclusion.

Design record
Criteria
  • The solution must address the stated need in recommendation CER.
  • The decision must be supported by E1-E3.
  • The final product must make the success criteria visible.
Constraints
  • Complete the work inside the 80-minute block.
  • Use only supplied or teacher-approved materials and evidence.
  • Do not trade , accessibility, or privacy for speed.
Tradeoff weights
  • and evidence quality: must pass before scoring other criteria.
  • User need and effectiveness: highest scored criterion.
  • Time, cost, and ease of use: compare only after and effectiveness pass.

Test evidence: For each option, record the E1-E3 result that supports or fails each criterion. Do not assign a score without a named observation.

Iteration log
  1. Version or option tested
  2. Criterion met or missed
  3. Evidence ID and result
  4. Revision made
  5. Reason for the revision
Decision record
  1. Need and user
  2. Criteria and constraints
  3. Chosen option and evidence
  4. Test result
  5. Revision and reason
Watch the trap

Students often think Students think a CER claim can name a symptom cluster like 'fatigue and high blood sugar' and count as a diagnosis.. The trap: That is a trap because a diagnosis must name a specific condition, not just describe the symptoms. Symptoms are the evidence pointing at the condition; if your claim only restates the symptoms, you have not actually diagnosed anything, and you cannot recommend a confirmatory test for a symptom list.

Worked example · a parallel case (guides, does not reveal)
Worked CER on a parallel case
Completes: A claim-evidence-reasoning paragraph naming the most likely diagnosis, citing multi-source workup evidence, recommending confirmatory next steps, and stating one limitation.

Claim: Patient B's most likely diagnosis is iron-deficiency anemia.\n\nEvidence: The history notes ongoing fatigue, feeling cold, and heavy menstrual periods; the complete blood count shows hemoglobin at 9.8 g/dL (below the 12.0 to 15.5 g/dL normal range for adult females) with small, pale red cells; and the physical exam finds pale inner eyelids and a resting heart rate of 98 beats per minute.\n\nReasoning: These sources converge on one story. The history points to steady blood loss and a body working harder to move oxygen, the low hemoglobin with small pale cells is the direct laboratory signature of too little iron to build normal red blood cells, and the pale eyelids plus faster heart rate are the body compensating for reduced oxygen-carrying capacity. Next steps: I recommend a serum ferritin test to confirm depleted iron stores, since ferritin measures the actual iron reserve rather than just the downstream red-cell count. Limitation: a low hemoglobin alone does not prove the cause, because other conditions such as chronic disease can also lower it, so the ferritin result is needed before the diagnosis is final.

Why this matters

This model shows the level of evidence and organization needed to complete: A claim-evidence-reasoning paragraph naming the most likely diagnosis, citing multi-source workup evidence, recommending confirmatory next steps, and stating one limitation.

Build yours step by step
  1. Write one defensible claim.
  2. Choose specific evidence that supports the claim.
  3. Explain the scientific rule that connects the evidence to the claim.
Change it for a new task

Keep the structure. Replace the question, facts, measurements, and evidence. Then recheck units, vocabulary, and whether the conclusion goes beyond the evidence.

Also due today: turns in the CER on Schoology under the Recommendation CER assignment before the end of the period.

See the full worked example
Portal terms
CER:
Claim, Evidence, Reasoning: make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure, the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities. Find it in Clever with your Microsoft sign-in, right next to Schoology.
This unit's vocabulary

Tap the speaker to hear a term. Add two of these to your notebook glossary with a definition and an example in your own words.

Build your vocabulary · optional, for extra credit

Pick just 2 or 3 words from today and make them yours: write what each one means in your own words, name the context clue or evidence that helped, then give one example from what you actually did in Recommendation CER. Try your own words first; the glossary is there if you get stuck. This is voluntary and counts as extra credit, so keep it short.

differential diagnosis
evidence synthesis
laboratory test
patient chart
recommendation

Saved on this device. Show Mr. Mendoza or add these to your notebook glossary to claim the extra credit.

Resources & readings

Hand-picked readings and interactives for this lesson, from authoritative open organizations and PLTW's own public course outline.

Practice: try a question, then check your answer

Claim ceiling for this check: Today's evidence supports a classroom claim about recommendation CER. It cannot prove causation, diagnose a real patient, or justify action outside this room.

Quick self-check · commit, then reveal

A student's CER claim reads: 'The patient has high blood sugar and is tired.' Is that a valid diagnostic claim? Fix it if not.

How sure are you?

Write an answer and pick a confidence to unlock the key.

Cumulative WebXam review · flash practice

Fast retrieval with instant answers, not the commit-then-reveal check above. Try each from memory first: write what you remember about the earlier units, then check yourself here.

Tap an answer to check it · nothing is recorded or graded
[Review: Decoding a Diagnosis: from DNA to protein] A bacterial transformation produces zero colonies even though the protocol was followed. Which is the most likely cause?
[Review: Genetic Risk: karyotypes, pedigrees, and diagnosing from mixed evidence] A genetic test reports a result without listing its false-positive rate. Why does that limit an evidence-based conclusion?
[Review: Genetic Risk: karyotypes, pedigrees, and diagnosing from mixed evidence] A genetic test reports a result without listing its false-positive rate. Why does that limit an evidence-based conclusion?
A patient with suspected bacterial infection has a complete blood count. Which result most supports infection?
Missed class or ready for more?
🔬 Pre-lab simulation

Run this before you touch the bench. It is built from the real lab procedure, so the decisions you make here are the ones you will make with the equipment in your hands.

The Bellyache: Close It Honestly
Open the simulation →
Where this leads: careers
What to do if you were absent
If YOU are absent

Today is individual work you can do from home: complete the same target above, then submit your CER.

FOR A GRADE
Open Schoology

Go to Schoology to turn this in. Submit one PDF. Put your first and last name in the document header. Name the file: FirstName LastName - Assignment Title - YYYY-MM-DD.pdf. If you cannot get in, see Mr. Mendoza. Do not skip the work.

If MR. MENDOZA is absent

Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:

NIH MedlinePlus Lab Tests
How this is graded
For: CER: CER with a specific diagnostic claim, multi-source evidence from the workup, reasoning linking each evidence point to the claim, a next-steps recommendation, and one stated limitation.
  • Complete
    Every required part of the artifact is present, nothing left blank.
  • Accurate
    The science and the data are correct and match the evidence.
  • Scientific reasoning
    You explain your claim with evidence and reasoning (CER), not just an answer.
  • Professional communication
    Clear, organized, labeled, and written the way a clinician or scientist would.
  • Submitted
    Go to Schoology to turn this in. Submit one PDF. Put your first and last name in the document header. Name the file: FirstName LastName - Assignment Title - YYYY-MM-DD.pdf. If you cannot get in, see Mr. Mendoza. Do not skip the work.