Thu, Sep 17, 2026Fall (Semester 1) · Week 4Day 18 of 7580-min block

Tissue and heart lab

Today's target

Examine histology slides under the microscope and observe gross heart anatomy following an SOP.

Due today · Lab report Required

Lab notebook pages: four histology sketches (one per tissue type, magnification labeled, one feature identified), a labeled heart diagram with chambers, valves, and major vessels, and one limitation and one error source noted.

Your 4 steps today
  1. 1
    Do this
    Examine histology slides under the microscope and observe gross heart anatomy following an SOP.
  2. 2
  3. 3
    Submit this
    Lab report: Lab notebook pages: four histology sketches (one per tissue type, magnification labeled, one feature identified), a labeled heart diagram with chambers, valves, and major vessels, and one limitation and one error source noted.
  4. 4
    Submit it here
    1. 1CMSD website. Go to clevelandmetroschools.org and click the Clever button.
    2. 2Clever. Clever opens. Sign in if it asks.
    3. 3Microsoft (district) login. Use your district Microsoft account (the one for school).
    4. 4Schoology. Open Schoology, then your class, then Assignments, and find the file named below.
    The file to submit is named: Principles of Biomedical Technology (Principles of Biomedical Science) › Unit 1.2 Master the Morgue: Body systems, toxicology evidence, tissue microscopy, gross anatomy, preserved-heart/autopsy alternative. › Lab report
    Open Schoology
Were you absent? Jump to the make-up plan
Where this fits
Tested on (Ohio WebXam)
Principles and Practice of Biomedical Technology · 072110
PLTW lesson
PBS · Tissue and heart lab
WebXam domain
Biotechnology Research and Experiments
Evidence to produce
Lab report
Lab / skill
Khan Academy: human body systems (Health and medicine)
Quick glossary
CER:
Claim, Evidence, Reasoning — make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure — the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities — you open it through Schoology.
Learn first

Minute-by-minute · 80-minute block

💡 Big idea: Histology bridges the microscopic world of cells to the macroscopic world of organs, giving pathologists the evidence to determine cause of death.

  1. 0:00Review SOP for microscopy and heart examination; PPE check before anyone opens specimen containers
  2. 0:10Microscopy station: four prepared histology slides; identify and sketch each at 40x and 100x
  3. 0:40Heart anatomy station: examine preserved heart; locate and label four chambers, four valves, major vessels
  4. 1:05Record one limitation of slide-based identification and one error source in lab notebook
  5. 1:05Station cleanup per SOP: cover specimens, return slides to tray, clean microscope stage
  6. 1:10Preview Thursday analysis; brief debrief on what surprised students
Mr. Mendoza's 5-minute intro
  • Today is the first major hands-on lab of this unit. You are going to look at real tissue under a real microscope and examine a preserved heart.
  • Before you touch the microscope: read the SOP. Set your stage at the lowest magnification first, focus, then increase. Skipping this step cracks slides.
  • The preserved heart is in fixative. The fixative keeps it from decomposing, but it is a chemical and you will wear gloves and work in a ventilated area. The smell is formaldehyde or a formalin substitute. Do not put your face near the specimen container.
  • You are scientists today. Every sketch goes in the notebook with magnification labeled. Every heart structure you identify gets labeled on a diagram. This is your evidence.
Do this, step by step
  1. 1Read the microscopy SOP and set magnification and focus correctly.
  2. 2Identify epithelial, connective, muscle, and nervous tissue on slides.
  3. 3Sketch each tissue with magnification and one identifying feature labeled.
  4. 4Examine a preserved heart and locate chambers, valves, and vessels.
  5. 5Record one limitation of slide-based identification and one error source.
You'll be able to
  • I can identify the four tissue types under magnification.
  • I can locate the major structures of the heart.
Know by the end
  • Magnification must always be recorded with a microscopy sketch because the apparent size of a structure is meaningless without it.
  • The heart has four chambers (right/left atria and ventricles), four valves (tricuspid, pulmonary, mitral, aortic), and its wall is primarily cardiac muscle tissue.
  • Preserved specimens have altered texture, color, and smell compared to fresh tissue; fixative chemicals require PPE and ventilation.
📺 Tutor me: learn.genetics: Cell Size and Scale
Do the work

Your PLTW work today

Open this PLTW section today

Unit 1.2 Master the Morgue: Body systems, toxicology evidence, tissue microscopy, gross anatomy, preserved-heart/autopsy alternative. · Tissue and heart lab

Day 3 of this lesson. Open this exact section in myPLTW (reached through Schoology), then do the work below.

Do this: In myPLTW, open the Lesson 1.2 Master the Morgue lab activity and record your slide observations and heart-anatomy labels.

Complete

Mark the Lesson 1.2 lab observation task started in myPLTW.

How far to get

You took notes on tissue types Tuesday. Today all four tissue sketches and the heart-anatomy diagram should be in your notebook before cleanup.

Upload as evidence

Notebook page with four labeled histology sketches (magnification noted) and a labeled heart diagram submitted through the tracker.

All PLTW activities are completed inside the PLTW course environment — this page only gives direction. Submit producibles on Schoology.

The plan

Today's PLTW tracker

Check things off as you work, then submit. This tells Mr. Mendoza how you're doing so he can help the class. It does not replace turning in your producible on Schoology.

Use the code Mr. Mendoza gave you, not your name. Saved on this device.

Unit 1.2 Master the Morgue: Body systems, toxicology evidence, tissue microscopy, gross anatomy, preserved-heart/autopsy alternative.Day 3 of this projectSee the full week plan
Today's PLTW target

Unit 1.2 Master the Morgue: Body systems, toxicology evidence, tissue microscopy, gross anatomy, preserved-heart/autopsy alternative. · Tissue and heart lab

In myPLTW, open the Lesson 1.2 Master the Morgue lab activity and record your slide observations and heart-anatomy labels.

You took notes on tissue types Tuesday. Today all four tissue sketches and the heart-anatomy diagram should be in your notebook before cleanup.

This is how Mr. Mendoza sees the class keeping pace with PLTW. Be honest, it only helps if it is accurate.

1 · What you do today

🎯 Examine histology slides under the microscope and observe gross heart anatomy following an SOP.

  • Read the microscopy SOP and set magnification and focus correctly.
  • Identify epithelial, connective, muscle, and nervous tissue on slides.
  • Sketch each tissue with magnification and one identifying feature labeled.
  • Examine a preserved heart and locate chambers, valves, and vessels.
  • Record one limitation of slide-based identification and one error source.
2 · Turn in today

Lab report: Lab notebook pages: four histology sketches (one per tissue type, magnification labeled, one feature identified), a labeled heart diagram with chambers, valves, and major vessels, and one limitation and one error source noted.

Submit on Schoology

Upload by 11:29 PM for full credit.

3 · Who's doing what (team)
TaskWho
Read the microscopy SOP and set magnification and focus correctly._______
Identify epithelial, connective, muscle, and nervous tissue on slides._______
Sketch each tissue with magnification and one identifying feature labeled._______
Examine a preserved heart and locate chambers, valves, and vessels._______
Record one limitation of slide-based identification and one error source._______

Working solo? Put your own name in "Who" for every row.

4 · Words I can use correctly
5 · I'm successful today when I can…
  • I can identify the four tissue types under magnification.
  • I can locate the major structures of the heart.
6 · Reflection & next steps
Where are you today?0/7 checked
Pick your period and code first.
Explore

Resources & readings

Hand-picked materials for this lesson. Class file items open the document directly; the rest are vetted readings and interactives from other biomedical programs.

Lab day

Lab & supplies

Bring / set up
Compound microscopes (one per group of 2-3 students)Prepared histology slides: epithelial tissue, connective tissue (e.g., hyaline cartilage), cardiac or skeletal muscle, and nervous tissue (e.g., spinal cord cross-section)Lens paper and lens-cleaning solutionPreserved mammalian heart (e.g., sheep or pig heart) in sealed specimen trayDissection tray or large aluminum panBlunt probe or wooden applicator sticks for heart examinationNitrile gloves (multiple sizes)Chemical splash gogglesLab apronsPaper towels and waste bagsVentilation (open windows or work under fume hood if available)
Safety / SOP
  • Preserved specimens contain fixative chemicals (formaldehyde or formalin substitute): wear nitrile gloves and goggles at all times at the heart station; work in a well-ventilated area.
  • Do not inhale deeply over an open specimen container; if you feel lightheaded or notice strong fume odor, move away and notify the teacher.
  • Histology slides are glass: handle by the edges only; place cracked or broken slides in the designated sharps container immediately.
  • Never touch the microscope lens with anything other than lens paper; do not use paper towels or your clothing to clean optics.
  • After the heart examination, seal the specimen tray, remove gloves using the glove-to-glove technique, and wash hands with soap and water for at least 20 seconds.
  • Dispose of all gloves, paper towels, and disposable materials used at the heart station in the labeled biological-waste bag, not the regular trash.
Khan Academy: human body systems (Health and medicine)
Words

This unit's vocabulary

homeostasis/hoh-mee-oh-STAY-sis/tissueorgan systemtoxicology/tok-sih-KOL-uh-jee/histology/his-TOL-uh-jee/mechanism of death

Tap the speaker to hear a term. Weekly vocabulary task: add two of these terms to your notebook glossary with a definition and an example in your own words.

Check yourself

WebXam practice

Tap an answer to check it · nothing is recorded or graded
To preserve incubated, refrigerated, and frozen substances, what should you closely monitor?
A glass slide carrying a live bacterial smear breaks. Where should it be disposed of?
You plate E. coli and notice a second species grew after 24 hours. What best explains this?
Before handling a specimen under the microscope, which practice best maintains a contamination-free workspace?
Check yourself

Cumulative WebXam review

A quick mixed-review pulling questions from earlier units plus today, so the WebXam material stays fresh.

Tap an answer to check it · nothing is recorded or graded
[Review: Course Launch: your lab notebook, PPE, and the language of evidence] Your analytical balance performance verification shows the standard's mass reads too low. What is the next step?
[Review: Investigating the Scene: documenting evidence like a forensic scientist] A researcher records a mistake in a notebook. What is the legally and scientifically correct way to handle it?
[Review: From Scene to Lab: designing evidence tests and meeting biomolecules] A researcher measures the zone of inhibition created by different mouthwashes. What is the dependent variable?
To preserve incubated, refrigerated, and frozen substances, what should you closely monitor?
Explore

Where this leads — careers

Safety net

What to do if you were absent

Today was a lab — do this instead

Use the virtual histology and heart-anatomy resources to identify all four tissue types and label heart structures, submitting sketches with magnification noted.

learn.genetics Inside a Cell

Then submit your Lab report on Schoology.

If MR. MENDOZA is absent

Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:

Khan Academy: human body systems (Health and medicine)
How this is graded
For: Lab report — Lab notebook pages: four histology sketches (one per tissue type, magnification labeled, one feature identified), a labeled heart diagram with chambers, valves, and major vessels, and one limitation and one error source noted.
  • Complete
    Every required part of the artifact is present, nothing left blank.
  • Accurate
    The science and the data are correct and match the evidence.
  • Scientific reasoning
    You explain your claim with evidence and reasoning (CER), not just an answer.
  • Professional communication
    Clear, organized, labeled, and written the way a clinician or scientist would.
  • Submitted
    Turned in the right way (Schoology for routine work) and confirmed.
Submission Zone

Drop your Thu, Sep 17, 2026 · Tissue and heart lab here. Use a clear file name (your initials + project). Routine work still goes to Schoology (via the CMSD portal).

Upload a project