Tue, Mar 2, 2027Spring (Semester 2) · Week 7Day 23 of 6180-min blockCalendar fit

Research design ticket

Essential question: Is it smarter to learn a design lesson from someone else's failed study, or from your own?Enduring understanding: Critiquing another study's flaws is the cheapest way to design a better one, because every uncontrolled variable you spot in their work becomes a requirement you build into yours.

Do now

Submit a research design ticket that critiques a study and proposes a sound physiology design.

DueTonight, 11:29 PM
Hand in
Problem 2 research design ticket: study critique identifying variable/control/limitation flaws, plus a proposed sound design with hypothesis, variables, and planned measurements.
Where
Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

You get two school days for every day you were absent, so this deadline moves with you.

Where you are · this course
Evidence-based revision, Q&A, intro to physiology research design. Research design ticket ▸ Day 5
Day 23 of 61 this semester38 left before WebXam
🧬 Where you are · PLTW
Biomedical InnovationProblem 2: Exploring Human Physiology"Project 2.1.1 Scientific Research"
Matched to your live myPLTW course (verified June 2026).
Today's driving question

Given a flawed physiology study summary, can you name exactly what went wrong and turn each flaw into a design rule for your own Problem 2 study?

Today you'll be able to

Submit a research design ticket that critiques a study and proposes a sound physiology design.

You've got it when
  • You can critique a study's design choices.
  • Your proposed design controls variables and is testable.
Due today · Exit ticket RequiredProblem 2 research design ticket: study critique identifying variable/control/limitation flaws, plus a proposed sound design with hypothesis, variables, and planned measurements.
Do-Now · start these with your notes closed
  1. Name one thing that could make a heart rate study give a wrong answer even if nobody cheated.
  2. If two groups in a study were tested at different times of day, why might that ruin the results?
Do this · step by step
numbered so we can always find our place
  1. 1Read a short provided physiology study summary.
  2. 2Critique its design: variables, controls, and limitations.
  3. 3Propose how you would design your own study to avoid those flaws.
  4. 4State your hypothesis, variables, and planned measurements.
  5. 5Submit the Problem 2 research design ticket.
Interrupted or lost? Lost your place? Check whether you have critiqued the provided study's variables, controls, and limitations. If yes, move to proposing your own flaw-free design and stating your hypothesis and measurements; if not, reread the study summary and start the critique.
Optional project open: Microbiology & the Working Lab - solo or group, about 3 to 4 hours total. Due by Fri, May 28, 2027. Great WebXam prep.
The story

What did this day actually feel like?

Research design ticket

A testable question with variables defined. Mine was too broad twice before it was answerable.

Turned in: exit ticket → Exit Tickets folder

Fiction. There is no such student. The lessons, labs and dates are the real planned course; the student, the classmates and the conversations are invented.

The comic

The same day, drawn.

Drawing, panel 30: Research design ticket.

A testable question with variables defined. Mine was too broad twice before it was answerable.

Panel 30Research design ticket · 2027-03-02
Read week 6, 6 panels

Fiction. There is no such student. The lessons, labs and dates are the real planned course; the student, the classmates and the conversations are invented.

🛠 Get unstuck · pick your level

Need a running start
Before critiquing, ask one question of the study: what did they change, and what did they forget to hold still? Finding the forgotten control is most of the critique.
On track
Critique the study's variables, controls, and limitations using named criteria, then turn each flaw into a design requirement for your own hypothesis, variables, and planned measurements.
Stuck? Get unstuck
Missed class? Use the study summary and one guiding question: name one uncontrolled variable and one thing it would ruin. Then write a single design rule that fixes it. Submit the critique and rule.
Push me further
Find a flaw in the study that most readers would miss (sample size, order effects, measurement timing) and show how ignoring it could flip the conclusion entirely.

🔑 Today's words · 5

iterationfeedbackusabilityhypothesisvariable
+1 more in the word bank

Tap a word in the lesson for a plain meaning and one example. Recycled into next week's Do-Now.

Today's study notebook
Presenting a design and defining the physiology variables that measure how the body works.
Open the notebook
Watch first: today's 1-minute intro
Audio overviewVideo overviewMind mapStudy guideFlashcardsQuizData table
Where this fits
Tested on (Ohio WebXam)
Biotechnology for Health and Disease · 072125 (likely, pending confirmation)
PLTW lesson
BI · Problem 2: Exploring Human Physiology
WebXam domain
Microbiology Testing and Technology
Evidence to produce
Exit ticket
Do the work · 80-minute blockfirst 5 min = hook

💡 Big idea: Critiquing another study's flaws makes your own design safer, because every flaw you catch in their work becomes a requirement in yours, so you avoid their mistakes on paper instead of in your data.

  1. 0-10Introduce the study-critique framework: variables, controls, , and limitations
  2. 10-30Read the provided physiology study summary and annotate design choices
  3. 30-50Critique: identify variable, control, and limitation problems in the study
  4. 50-65Propose your own study design that avoids those flaws: hypothesis, variables, and planned measurements
  5. 65-77Submit the Problem 2 research design ticket
  6. 77-80Exit check: name the most important design improvement your proposed study makes
Mr. Mendoza's 5-minute intro
  • Today you read a short physiology study summary and pull it apart -- not to criticize, but to learn from its design choices.
  • Every flaw you find in someone else's study is a mistake you will not make in your own.
  • Then you will propose a sound design of your own and document it as your Friday summative.
  • Study-design critique is a direct skill for the Molecular and Genetic Technology and Microbiology Testing strands of WebXam 072125.
Know by the end
  • How to evaluate a study's variable identification, controls, and limitations using named criteria.
  • How the flaws in a study become the design requirements for a better one.
  • What a sound physiology study design looks like when variables are controlled and the hypothesis is testable.
Open this PLTW section today

Evidence-based revision, Q&A, intro to physiology research design. · Research design ticket

Day 5 of this lesson. Open this exact section in myPLTW (find it in Clever, Microsoft sign-in), then do the work below.

Do this: Open Problem 2 in your myPLTW course shell and locate the research-design or study-critique activity to review the critique format.

Complete

Mark the research-design ticket activity complete in your tracker after submitting.

How far to get

The Problem 2 variable and hypothesis work is done; by end of today the study critique and your proposed physiology design should be submitted as the weekly summative.

Upload as evidence

Research design ticket with study critique and your proposed design including hypothesis, variables, and planned measurements.

The official PLTW activity stays inside myPLTW. If myPLTW will not open, use F1 and E1-E3 on this page to complete today's local evidence decision, then make up the official activity when access returns. Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

Today's PLTW tracker · fill in and submit

Check things off as you work, then submit. This tells Mr. Mendoza how you're doing so he can help the class. It does not replace turning in your producible through the submission route shown below.

Use the code Mr. Mendoza gave you, not your name. Saved on this device.

Evidence-based revision, Q&A, intro to physiology research design.Day 5 of this projectSee the full week plan
Today's PLTW target

Evidence-based revision, Q&A, intro to physiology research design. · Research design ticket

Open Problem 2 in your myPLTW course shell and locate the research-design or study-critique activity to review the critique format.

The Problem 2 variable and hypothesis work is done; by end of today the study critique and your proposed physiology design should be submitted as the weekly summative.

This is how Mr. Mendoza sees the class keeping pace with PLTW. Be honest, it only helps if it is accurate.

1 · What you do today

🎯 Submit a research design ticket that critiques a study and proposes a sound physiology design.

  • Read a short provided physiology study summary.
  • Critique its design: variables, controls, and limitations.
  • Propose how you would design your own study to avoid those flaws.
  • State your hypothesis, variables, and planned measurements.
  • Submit the Problem 2 research design ticket.
2 · What you turn in

Exit ticket: Problem 2 research design ticket: study critique identifying variable/control/limitation flaws, plus a proposed sound design with hypothesis, variables, and planned measurements.

Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not. Use the checklist just below and upload by 11:29 PM for full credit. Absent with an excused absence? You get two school days for every day you were absent, so this deadline moves with you.

3 · Who's doing what (team)
TaskWho
Read a short provided physiology study summary._______
Critique its design: variables, controls, and limitations._______
Propose how you would design your own study to avoid those flaws._______
State your hypothesis, variables, and planned measurements._______
Submit the Problem 2 research design ticket._______

Working solo? Put your own name in "Who" for every row.

4 · Words I can use correctly
5 · I'm successful today when I can…
  • You can critique a study's design choices.
  • Your proposed design controls variables and is testable.
6 · Reflection & next steps
Where are you today?0/7 checked
Pick your period and code first.
Your 4 steps today
  1. 1
    Do this
    Submit a research design ticket that critiques a study and proposes a sound physiology design.
  2. 2
  3. 3
    Submit this
    Exit ticket: Problem 2 research design ticket: study critique identifying variable/control/limitation flaws, plus a proposed sound design with hypothesis, variables, and planned measurements.
  4. 4
    Submit it here
    1. 1Open the drop folder.
    2. 2Sign in with your district Microsoft account, not a personal one.
    3. 3Upload the file, named Lastname_Firstname__Assignment Title.
    4. 4Your own upload panel says Uploaded with a green check: that is your receipt.
    Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not. Biotechnology for Health (Biomedical Innovations) › Evidence-based revision, Q&A, intro to physiology research design. › Exit ticket
    Open the drop folder
Were you absent? Jump to the make-up plan
Learn it · deck, reading, and vocabulary
Socratic teaching slide deck

The deck carries the prior idea forward, lets you inspect an analogy, maps the rule to biology, and ends with the same evidence decision and exit ticket used on this page.

Generated from this lesson's canonical data with a red-team citation check.

Carry forward

You must define your variables and a testable hypothesis first so that your measurements mean something, because an undefined study cannot tell you what actually caused a change.

Daily take-home

Critiquing another study's flaws makes your own design safer, because every flaw you catch in their work becomes a requirement in yours, so you avoid their mistakes on paper instead of in your data.

Inspect the analogy

A bridge prototype is tested against a load limit, cost limit, and user need before revision.

  1. Which requirement is a criterion?
  2. Which limit is a constraint?
  3. What test result should trigger a redesign?
Rule

A design improves when evidence is compared with explicit criteria and constraints.

Where it breaks

Biomedical designs also require , ethics, and biological validation beyond a physical prototype test.

Map the analogy to biology
  • Bridge requirements map to design criteria.
  • Load results map to E1-E3.
  • Revision maps to the next evidence-based iteration.
Read this first

Driving question: Given a flawed physiology study summary, can you name exactly what went wrong and turn each flaw into a design rule for your own Problem 2 study?

What you already know: You must define your variables and a testable hypothesis first so that your measurements mean something, because an undefined study cannot tell you what actually caused a change.

New idea: Critiquing another study's flaws makes your own design safer, because every flaw you catch in their work becomes a requirement in yours, so you avoid their mistakes on paper instead of in your data.

Visual or model: F1. F1. A lesson illustration or teaching diagram for Research design ticket. Use it with E1-E3; it is a model or context image, not experimental or patient data. What to notice: Trace the labeled system, test, or design relationship and identify which evidence should trigger revision.

  1. Observe or measure the relevant feature in Research design ticket.
  2. Organize the observation with a stable evidence ID.
  3. Apply this rule: A design improves when evidence is compared with explicit criteria and constraints.
  4. Choose the option the evidence supports and state the limit of the conclusion.

Real biomedical example: Given a flawed physiology study summary, can you name exactly what went wrong and turn each flaw into a design rule for your own Problem 2 study?

What the evidence supports: E1-E3 and F1 support the daily take-home when the response meets the stated success criteria.

What it cannot prove: The package does not support claims beyond this lesson's or any real patient diagnosis.

Vocabulary:
  • iteration: One repeated cycle of building, testing, and improving, where each pass refines the design or result based on what the last pass revealed.
  • feedback: A loop in which the output of a process feeds back to adjust the process itself, either damping change (negative) or amplifying it (positive).
  • usability: How easy, efficient, and satisfying a product is for its intended users to learn and use to reach their goals.
  • hypothesis: A testable, falsifiable prediction about how variables relate, written so an experiment can support it or prove it wrong.
  • variable: Any factor in an experiment that can change or be changed, including what you test, what you measure, and what you hold steady.
  • control: The comparison condition that isolates the effect of the variable being tested by keeping everything else the same.

Use it now: Choose one decision option. Cite E1 and E3, then explain how the rule connects the evidence to your choice.

Go further, optional: The source links below are optional enrichment. Every fact required for today's local evidence decision appears in this lesson package.

Evidence set and decision
E1 · Observation

How to evaluate a study's variable identification, controls, and limitations using named criteria.

Limit: E1 supplies context or an observation; it does not by itself establish the explanation.

E2 · Mechanism

Critiquing another study's flaws makes your own design safer, because every flaw you catch in their work becomes a requirement in yours, so you avoid their mistakes on paper instead of in your data.

Limit: E2 is a teaching statement or comparison and must be checked against the task evidence.

E3 · Result

You can critique a study's design choices.

Limit: E3 supports only the result or product criterion named here; it cannot justify a broader clinical or causal claim.

PLTW-BFH-2027-03-02 · Simulated classroom evidence scenario

Your role: biomedical design team member

Decision: Your team must decide what the evidence from Research design ticket supports before submitting the exit response named on the lesson page.

  • Keep the current design.
  • Revise the feature that misses a criterion.
  • Run one more fair test before choosing.

Response: State one choice, cite at least two evidence IDs, explain the rule that connects them, and add one limitation. Submit it as the exit response.

Claim ceiling: The supplied lesson evidence can support an observation, pattern, classroom mechanism, or next-step decision about Research design ticket. It cannot by itself prove causation, establish a real clinical diagnosis, or justify action outside this classroom task.

Math moment
Formula or setup

Rate or percent = part / comparison total x 100%. Percent change = (new - comparison) / comparison x 100%.

Worked parallel example

If 18 of 60 records meet a condition, the frequency is 18 / 60 x 100% = 30%.

Units and reasonableness

Name the comparison total. A percent describes the supplied group and does not automatically predict an individual's outcome.

Try it with today's data

Use today's supplied counts to calculate one rate, risk, frequency, or percent change. Show the denominator and interpretation.

Design record
Criteria
  • The solution must address the stated need in Research design ticket.
  • The decision must be supported by E1-E3.
  • The final product must make the success criteria visible.
Constraints
  • Complete the work inside the 80-minute block.
  • Use only supplied or teacher-approved materials and evidence.
  • Do not trade , accessibility, or privacy for speed.
Tradeoff weights
  • and evidence quality: must pass before scoring other criteria.
  • User need and effectiveness: highest scored criterion.
  • Time, cost, and ease of use: compare only after and effectiveness pass.

Test evidence: For each option, record the E1-E3 result that supports or fails each criterion. Do not assign a score without a named observation.

Iteration log
  1. Version or option tested
  2. Criterion met or missed
  3. Evidence ID and result
  4. Revision made
  5. Reason for the revision
Decision record
  1. Need and user
  2. Criteria and constraints
  3. Chosen option and evidence
  4. Test result
  5. Revision and reason
Watch the trap

Students often think Students often think a study is trustworthy if the researchers were honest and collected real data, so an honest study must have a valid conclusion.. The trap: That is a trap because honesty does not fix design; an uncontrolled variable can hand you a real, honestly measured number that still answers the wrong question, which is exactly why you critique the design, not the intentions.

Worked example · a parallel case (guides, does not reveal)
Research design ticket
Completes: A ticket that critiques a sample physiology study's design and proposes a sound study with a testable hypothesis, controlled variables, and planned measurements.

Problem 2 research design ticket

Study I critiqued (summary provided in class): a study claimed that drinking coffee raises heart rate, based on measuring 4 people once after coffee, with no resting baseline.

Design flaws:

  • No control or baseline: there is no before-coffee reading to compare against.
  • Tiny sample: 4 people cannot represent a population reliably.
  • Uncontrolled variables: activity and time of day were not held constant.

My improved design:

  • Hypothesis: If a person drinks caffeinated coffee, then their heart rate will rise compared to a measured baseline.
  • Variables: independent, caffeine versus no caffeine; dependent, heart rate; controlled, same people, same rest, same time of day.
  • Planned measurements: resting heart rate, then heart rate 30 minutes after the drink, repeated for each person, with at least 12 participants.

Why this is better: it adds a baseline, controls variables, and uses a larger sample, so the conclusion would actually be interpretable.

Why this matters

This model shows the level of evidence and organization needed to complete: A ticket that critiques a sample physiology study's design and proposes a sound study with a testable hypothesis, controlled variables, and planned measurements.

Build yours step by step
  1. Name the prompt or task.
  2. Answer it directly with the key evidence.
  3. Check that the response matches the requested format.
Change it for a new task

Keep the structure. Replace the question, facts, measurements, and evidence. Then recheck units, vocabulary, and whether the conclusion goes beyond the evidence.

Also due today: Submit the Problem 2 research design ticket on the class site, or hand it to Mr. Mendoza in class.

See the full worked example
Portal terms
CER:
Claim, Evidence, Reasoning: make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure, the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities. Find it in Clever with your Microsoft sign-in, right next to Schoology.
This unit's vocabulary
/hy-POTH-uh-sis/

Tap the speaker to hear a term. Add two of these to your notebook glossary with a definition and an example in your own words.

Build your vocabulary · optional, for extra credit

Pick just 2 or 3 words from today and make them yours: write what each one means in your own words, name the context clue or evidence that helped, then give one example from what you actually did in Research design ticket. Try your own words first; the glossary is there if you get stuck. This is voluntary and counts as extra credit, so keep it short.

iteration
feedback
usability
hypothesis
variable
control

Saved on this device. Show Mr. Mendoza or add these to your notebook glossary to claim the extra credit.

Teacher-posted resources

Classroom documents for this lesson are posted in Schoology. Open Clever, then Schoology, and find each one by the name shown on its card.

Catch-up / reteachFor: Need extra support
PLTW BI Mission File 1 Clinical Medicine & ER Innovation Overview
worksheet/handoutPosted in Schoology
Open in Schoology

Use this if you were absent, got stuck, or need another pass before you submit the lesson artifact.

Placement rationale

Matched ER presentation and physiology bridge by path:Biomedical-Innovations/Problem-1_Emergency-Room/1.1_Emergency-Room; keywords:emergency room, clinical. Score 142. Visibility: student-schoology (student-facing resource; link through Schoology rather than local path).

Use during lessonFor: Everyone
BI Project 2.1.1 Scientific Research Student Activity
worksheet/handoutPosted in Schoology
Open in Schoology

Open this when the class reaches this activity and use it to complete the required lesson artifact.

Placement rationale

Matched ER presentation and physiology bridge by path:Biomedical-Innovations/Problem-2_Human-Physiology/2.1_Human-Physiology; keywords:physiology. Score 134. Visibility: student-schoology (student-facing resource; link through Schoology rather than local path).

Use during lessonFor: Everyone
PLTW BI Activity 2.1.2 Science and the Media
worksheet/handoutPosted in Schoology
Open in Schoology

Open this when the class reaches this activity and use it to complete the required lesson artifact.

Placement rationale

Matched ER presentation and physiology bridge by path:Biomedical-Innovations/Problem-2_Human-Physiology/2.1_Human-Physiology; keywords:physiology. Score 134. Visibility: student-schoology (student-facing resource; link through Schoology rather than local path).

How to get there: open Clever and sign in with your Microsoft (district) account. Both myPLTW and Schoology are in Clever. Do the activity in myPLTW. Turn the work in on this site or hand it to Mr. Mendoza, because that is the step that counts as submitted. Schoology only shows your report-card grade later.

Check yourself · commit, then reveal

Claim ceiling for this check: The supplied lesson evidence can support an observation, pattern, classroom mechanism, or next-step decision about Research design ticket. It cannot by itself prove causation, establish a real clinical diagnosis, or justify action outside this classroom task.

Quick self-check · commit, then reveal

A study finds a supplement 'raised energy,' but everyone took it right after lunch. What is the design flaw, and what does it do to the conclusion?

How sure are you?

Write an answer and pick a confidence to unlock the key.

Cumulative WebXam review · flash practice

Fast retrieval with instant answers, not the commit-then-reveal check above. Try each from memory first: write what you remember about the earlier units, then check yourself here.

Tap an answer to check it · nothing is recorded or graded
[Review: Designing a better ER: triage, patient flow, and stakeholder needs] A co-worker from another lab wants to use your microscope. What should you ask them to do first?
[Review: Finding the truth: credible sources, prior art, and needs assessment] After finding the experimental group had lower glucose than the placebo group, what is the next step?
[Review: Prototyping the ER: floor plans, process flow, and human factors] How should you properly prepare hydrochloric acid (HCl) for disposal?
You are measuring the rate that catalase breaks down hydrogen peroxide. What is the dependent variable?
Go further and get help
Where this leads: careers
What to do if you were absent
If YOU are absent

Today is individual work you can do from home: complete the same target above, then submit your Exit ticket.

Open the drop folder

Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

If MR. MENDOZA is absent

Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:

Khan Academy Scientific Method
How this is graded
For: Exit ticket: Problem 2 research design ticket: study critique identifying variable/control/limitation flaws, plus a proposed sound design with hypothesis, variables, and planned measurements.
  • Complete
    Every required part of the artifact is present, nothing left blank.
  • Accurate
    The science and the data are correct and match the evidence.
  • Scientific reasoning
    You explain your claim with evidence and reasoning (CER), not just an answer.
  • Professional communication
    Clear, organized, labeled, and written the way a clinician or scientist would.
  • Submitted
    Turned in the right way, on the class site or handed to Mr. Mendoza in class, and confirmed. Not in Schoology: that is where the report-card grade appears later.