Fri, Feb 26, 2027Spring (Semester 2) · Week 6Day 22 of 6180-min blockCalendar fit

Physiology variables

Essential question: Before you can measure anything about the human body, what do you have to nail down first?Enduring understanding: Every physiology investigation stands or falls on its variables and a testable hypothesis, because you cannot measure a change if you never defined what changes, what you watch, and what you hold still.

Do now

Launch Problem 2 by identifying variables for a human physiology research design.

DueTonight, 11:29 PM
Hand in
Problem 2 launch: chosen physiological measure, identified independent/dependent/controlled variables, and a testable hypothesis.
Where
Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

You get two school days for every day you were absent, so this deadline moves with you.

Where you are · this course
Evidence-based revision, Q&A, intro to physiology research design. Physiology variables ▸ Day 4
Day 22 of 61 this semester39 left before WebXam
🧬 Where you are · PLTW
Biomedical InnovationProblem 2: Exploring Human Physiology"Project 2.1.1 Scientific Research"
Matched to your live myPLTW course (verified June 2026).
Today's driving question

If you want to study how something affects heart rate, exactly which variable do you change, which do you measure, and which do you have to keep constant?

Today you'll be able to

Launch Problem 2 by identifying variables for a human physiology research design.

You've got it when
  • You can name independent, dependent, and controlled variables.
  • You can write a testable physiology hypothesis.
Due today · Exit ticket RequiredProblem 2 launch: chosen physiological measure, identified independent/dependent/controlled variables, and a testable hypothesis.
Do-Now · start these with your notes closed
  1. Your resting heart rate and your heart rate after climbing stairs are different numbers. Name the one thing that changed to cause it.
  2. If you wanted to test whether music changes heart rate, what would you have to keep the same for both listeners?
Do this · step by step
numbered so we can always find our place
  1. 1Read the Problem 2 physiology overview.
  2. 2Choose a physiological measure to investigate, such as heart rate.
  3. 3Identify the independent, dependent, and controlled variables.
  4. 4Write a testable hypothesis about your measure.
  5. 5Submit your variables and hypothesis.
Interrupted or lost? Lost your place? Check whether you have chosen a physiological measure and written your three variables. If yes, move to writing your testable hypothesis; if not, start by reading the Problem 2 overview and picking a measure such as heart rate.
Optional project open: Microbiology & the Working Lab - solo or group, about 3 to 4 hours total. Due by Fri, May 28, 2027. Great WebXam prep.
The story

What did this day actually feel like?

Physiology variables

New problem. Human physiology, and what you can actually measure on a person in a classroom: heart rate, reaction time, grip strength, breathing rate.

Turned in: exit ticket → Exit Tickets folder

Fiction. There is no such student. The lessons, labs and dates are the real planned course; the student, the classmates and the conversations are invented.

The comic

The same day, drawn.

Drawing, panel 29: Physiology variables.

New problem. Human physiology, and what you can actually measure on a person in a classroom: heart rate, reaction time, grip strength, breathing rate.

Panel 29Physiology variables · 2027-02-26
Read week 6, 6 panels

Fiction. There is no such student. The lessons, labs and dates are the real planned course; the student, the classmates and the conversations are invented.

🛠 Get unstuck · pick your level

Need a running start
Warm up by finishing three sentences about climbing stairs: I change ____, I measure ____, I keep ____ the same. Those three blanks are independent, dependent, and controlled variables.
On track
Choose a physiological measure, correctly label your independent, dependent, and controlled variables, and write a hypothesis that is testable rather than a guess.
Stuck? Get unstuck
Missed class? Read the Problem 2 overview, then use one everyday example (exercise and heart rate) to label all three variable types before applying them to your own measure. Submit both.
Push me further
Design your study with two controlled variables you might normally forget (time of day, caffeine) and explain in one line how each would distort your heart rate data if left uncontrolled.

🔑 Today's words · 5

iterationfeedbackusabilityhypothesisvariable
+1 more in the word bank

Tap a word in the lesson for a plain meaning and one example. Recycled into next week's Do-Now.

Today's study notebook
Presenting a design and defining the physiology variables that measure how the body works.
Open the notebook
Watch first: today's 1-minute intro
Audio overviewVideo overviewMind mapStudy guideFlashcardsQuizData table
Where this fits
Tested on (Ohio WebXam)
Biotechnology for Health and Disease · 072125 (likely, pending confirmation)
PLTW lesson
BI · Problem 2: Exploring Human Physiology
WebXam domain
Microbiology Testing and Technology
Evidence to produce
Exit ticket
Do the work · 80-minute blockfirst 5 min = hook

💡 Big idea: You must define your variables and a testable hypothesis first so that your measurements mean something, because an undefined study cannot tell you what actually caused a change.

  1. 0-10Introduce Problem 2: physiology investigation overview and evidence expectations
  2. 10-25Read the Problem 2 physiology overview and discuss physiological measures worth studying
  3. 25-40Choose a measure and identify independent, dependent, and controlled variables
  4. 40-60Write a testable hypothesis linking the to the dependent measure
  5. 60-75Submit your variables and hypothesis
  6. 75-80Pair-check: does your partner's hypothesis have all three variable types? Give one piece of feedback.
Mr. Mendoza's 5-minute intro
  • Problem 1 is complete. Problem 2 asks you to investigate human physiology using real data.
  • Today you launch Problem 2 by choosing a physiological measure and designing a testable hypothesis around it.
  • Getting the variables right now prevents weeks of wasted data collection later.
  • Molecular and Genetic Technology and Microbiology Testing on WebXam 072125 both require experimental design fluency.
Know by the end
  • The definitions of independent, dependent, and controlled variables and how to apply them to a physiology investigation.
  • What makes a hypothesis testable rather than merely a guess.
  • Why choosing a measurable physiological variable -- such as heart rate -- is the first constraint that shapes the entire study design.
Open this PLTW section today

Evidence-based revision, Q&A, intro to physiology research design. · Physiology variables

Day 4 of this lesson. Open this exact section in myPLTW (find it in Clever, Microsoft sign-in), then do the work below.

Do this: Open Problem 2 Exploring Human Physiology in your myPLTW course shell and locate the variable-identification and hypothesis activity.

Complete

Mark the variable and hypothesis activity complete in your tracker after submitting your work.

How far to get

Problem 1 is fully closed out; today you launch Problem 2 by identifying variables and writing your first physiology hypothesis.

Upload as evidence

Written variable identification (independent, dependent, controlled) and a testable physiology hypothesis turned in on the class site or in person.

The official PLTW activity stays inside myPLTW. If myPLTW will not open, use F1 and E1-E3 on this page to complete today's local evidence decision, then make up the official activity when access returns. Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

Today's PLTW tracker · fill in and submit

Check things off as you work, then submit. This tells Mr. Mendoza how you're doing so he can help the class. It does not replace turning in your producible through the submission route shown below.

Use the code Mr. Mendoza gave you, not your name. Saved on this device.

Evidence-based revision, Q&A, intro to physiology research design.Day 4 of this projectSee the full week plan
Today's PLTW target

Evidence-based revision, Q&A, intro to physiology research design. · Physiology variables

Open Problem 2 Exploring Human Physiology in your myPLTW course shell and locate the variable-identification and hypothesis activity.

Problem 1 is fully closed out; today you launch Problem 2 by identifying variables and writing your first physiology hypothesis.

This is how Mr. Mendoza sees the class keeping pace with PLTW. Be honest, it only helps if it is accurate.

1 · What you do today

🎯 Launch Problem 2 by identifying variables for a human physiology research design.

  • Read the Problem 2 physiology overview.
  • Choose a physiological measure to investigate, such as heart rate.
  • Identify the independent, dependent, and controlled variables.
  • Write a testable hypothesis about your measure.
  • Submit your variables and hypothesis.
2 · What you turn in

Exit ticket: Problem 2 launch: chosen physiological measure, identified independent/dependent/controlled variables, and a testable hypothesis.

Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not. Use the checklist just below and upload by 11:29 PM for full credit. Absent with an excused absence? You get two school days for every day you were absent, so this deadline moves with you.

3 · Who's doing what (team)
TaskWho
Read the Problem 2 physiology overview._______
Choose a physiological measure to investigate, such as heart rate._______
Identify the independent, dependent, and controlled variables._______
Write a testable hypothesis about your measure._______
Submit your variables and hypothesis._______

Working solo? Put your own name in "Who" for every row.

4 · Words I can use correctly
5 · I'm successful today when I can…
  • You can name independent, dependent, and controlled variables.
  • You can write a testable physiology hypothesis.
6 · Reflection & next steps
Where are you today?0/7 checked
Pick your period and code first.
Your 4 steps today
  1. 1
    Do this
    Launch Problem 2 by identifying variables for a human physiology research design.
  2. 2
  3. 3
    Submit this
    Exit ticket: Problem 2 launch: chosen physiological measure, identified independent/dependent/controlled variables, and a testable hypothesis.
  4. 4
    Submit it here
    1. 1Open the drop folder.
    2. 2Sign in with your district Microsoft account, not a personal one.
    3. 3Upload the file, named Lastname_Firstname__Assignment Title.
    4. 4Your own upload panel says Uploaded with a green check: that is your receipt.
    Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not. Biotechnology for Health (Biomedical Innovations) › Evidence-based revision, Q&A, intro to physiology research design. › Exit ticket
    Open the drop folder
Were you absent? Jump to the make-up plan
Learn it · deck, reading, and vocabulary
Socratic teaching slide deck

The deck carries the prior idea forward, lets you inspect an analogy, maps the rule to biology, and ends with the same evidence decision and exit ticket used on this page.

Generated from this lesson's canonical data with a red-team citation check.

Carry forward

You must answer questions from your own evidence so that the panel trusts your design is real, because a confident guess that proves wrong destroys credibility instantly.

Daily take-home

You must define your variables and a testable hypothesis first so that your measurements mean something, because an undefined study cannot tell you what actually caused a change.

Inspect the analogy

A bridge prototype is tested against a load limit, cost limit, and user need before revision.

  1. Which requirement is a criterion?
  2. Which limit is a constraint?
  3. What test result should trigger a redesign?
Rule

A design improves when evidence is compared with explicit criteria and constraints.

Where it breaks

Biomedical designs also require , ethics, and biological validation beyond a physical prototype test.

Map the analogy to biology
  • Bridge requirements map to design criteria.
  • Load results map to E1-E3.
  • Revision maps to the next evidence-based iteration.
Read this first

Driving question: If you want to study how something affects heart rate, exactly which variable do you change, which do you measure, and which do you have to keep constant?

What you already know: You must answer questions from your own evidence so that the panel trusts your design is real, because a confident guess that proves wrong destroys credibility instantly.

New idea: You must define your variables and a testable hypothesis first so that your measurements mean something, because an undefined study cannot tell you what actually caused a change.

Visual or model: F1. F1. A lesson illustration or teaching diagram for Physiology variables. Use it with E1-E3; it is a model or context image, not experimental or patient data. What to notice: Trace the labeled system, test, or design relationship and identify which evidence should trigger revision.

  1. Observe or measure the relevant feature in Physiology variables.
  2. Organize the observation with a stable evidence ID.
  3. Apply this rule: A design improves when evidence is compared with explicit criteria and constraints.
  4. Choose the option the evidence supports and state the limit of the conclusion.

Real biomedical example: If you want to study how something affects heart rate, exactly which variable do you change, which do you measure, and which do you have to keep constant?

What the evidence supports: E1-E3 and F1 support the daily take-home when the response meets the stated success criteria.

What it cannot prove: The package does not support claims beyond this lesson's or any real patient diagnosis.

Vocabulary:
  • iteration: One repeated cycle of building, testing, and improving, where each pass refines the design or result based on what the last pass revealed.
  • feedback: A loop in which the output of a process feeds back to adjust the process itself, either damping change (negative) or amplifying it (positive).
  • usability: How easy, efficient, and satisfying a product is for its intended users to learn and use to reach their goals.
  • hypothesis: A testable, falsifiable prediction about how variables relate, written so an experiment can support it or prove it wrong.
  • variable: Any factor in an experiment that can change or be changed, including what you test, what you measure, and what you hold steady.
  • control: The comparison condition that isolates the effect of the variable being tested by keeping everything else the same.

Use it now: Choose one decision option. Cite E1 and E3, then explain how the rule connects the evidence to your choice.

Go further, optional: The source links below are optional enrichment. Every fact required for today's local evidence decision appears in this lesson package.

Evidence set and decision
E1 · Observation

The definitions of independent, dependent, and controlled variables and how to apply them to a physiology investigation.

Limit: E1 supplies context or an observation; it does not by itself establish the explanation.

E2 · Mechanism

You must define your variables and a testable hypothesis first so that your measurements mean something, because an undefined study cannot tell you what actually caused a change.

Limit: E2 is a teaching statement or comparison and must be checked against the task evidence.

E3 · Result

You can name independent, dependent, and controlled variables.

Limit: E3 supports only the result or product criterion named here; it cannot justify a broader clinical or causal claim.

PLTW-BFH-2027-02-26 · Simulated classroom evidence scenario

Your role: biomedical design team member

Decision: Your team must decide what the evidence from Physiology variables supports before submitting the exit response named on the lesson page.

  • Keep the current design.
  • Revise the feature that misses a criterion.
  • Run one more fair test before choosing.

Response: State one choice, cite at least two evidence IDs, explain the rule that connects them, and add one limitation. Submit it as the exit response.

Claim ceiling: The supplied lesson evidence can support an observation, pattern, classroom mechanism, or next-step decision about Physiology variables. It cannot by itself prove causation, establish a real clinical diagnosis, or justify action outside this classroom task.

Math moment
Formula or setup

Mean = sum of values / number of values. Median = middle ordered value. Range = maximum - minimum.

Worked parallel example

For 2, 4, 4, and 10: mean = 20 / 4 = 5, median = 4, and range = 10 - 2 = 8.

Units and reasonableness

Mean, median, and range keep the measurement unit. Order the values before finding the median.

Try it with today's data

Calculate the requested summary for today's supplied values, then write what it reveals and what it hides.

Design record
Criteria
  • The solution must address the stated need in Physiology variables.
  • The decision must be supported by E1-E3.
  • The final product must make the success criteria visible.
Constraints
  • Complete the work inside the 80-minute block.
  • Use only supplied or teacher-approved materials and evidence.
  • Do not trade , accessibility, or privacy for speed.
Tradeoff weights
  • and evidence quality: must pass before scoring other criteria.
  • User need and effectiveness: highest scored criterion.
  • Time, cost, and ease of use: compare only after and effectiveness pass.

Test evidence: For each option, record the E1-E3 result that supports or fails each criterion. Do not assign a score without a named observation.

Iteration log
  1. Version or option tested
  2. Criterion met or missed
  3. Evidence ID and result
  4. Revision made
  5. Reason for the revision
Decision record
  1. Need and user
  2. Criteria and constraints
  3. Chosen option and evidence
  4. Test result
  5. Revision and reason
Watch the trap

Students often think Students often think the is whatever they measure with an instrument, so they call heart rate the independent variable because that is the number they collect.. The trap: That is a trap because heart rate is the ; it responds. The is the thing you deliberately change, such as exercise or music, and mixing them up means your whole study answers the wrong question.

Worked example · a parallel case (guides, does not reveal)
Variables and hypothesis ticket
Completes: A Problem 2 launch ticket naming a physiological measure, its independent, dependent, and controlled variables, and a testable hypothesis.

Problem 2 launch: variables and hypothesis

Physiological measure I will investigate: heart rate.

Variables:

  • Independent (what I change): exercise level, sitting at rest versus 2 minutes of step-ups.
  • Dependent (what I measure): heart rate in beats per minute.
  • Controlled (what I keep the same): same person, same time of day, same step height and pace, 1-minute rest before each reading.

Testable hypothesis: If a person does 2 minutes of step-ups, then their heart rate will increase compared to their resting rate, because exercise raises the body's demand for oxygen and the heart pumps faster to meet it.

Why this is testable: it predicts a measurable change (heart rate) tied to a variable I control (exercise level), so I can confirm or disconfirm it with data.

Why this matters

This model shows the level of evidence and organization needed to complete: A Problem 2 launch ticket naming a physiological measure, its independent, dependent, and controlled variables, and a testable hypothesis.

Build yours step by step
  1. Name the prompt or task.
  2. Answer it directly with the key evidence.
  3. Check that the response matches the requested format.
Change it for a new task

Keep the structure. Replace the question, facts, measurements, and evidence. Then recheck units, vocabulary, and whether the conclusion goes beyond the evidence.

Also due today: Submit your variables and hypothesis on the class site, or hand it to Mr. Mendoza in class by end of period.

See the full worked example
Portal terms
CER:
Claim, Evidence, Reasoning: make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure, the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities. Find it in Clever with your Microsoft sign-in, right next to Schoology.
This unit's vocabulary
/hy-POTH-uh-sis/

Tap the speaker to hear a term. Add two of these to your notebook glossary with a definition and an example in your own words.

Build your vocabulary · optional, for extra credit

Pick just 2 or 3 words from today and make them yours: write what each one means in your own words, name the context clue or evidence that helped, then give one example from what you actually did in Physiology variables. Try your own words first; the glossary is there if you get stuck. This is voluntary and counts as extra credit, so keep it short.

iteration
feedback
usability
hypothesis
variable
control

Saved on this device. Show Mr. Mendoza or add these to your notebook glossary to claim the extra credit.

Teacher-posted resources

Classroom documents for this lesson are posted in Schoology. Open Clever, then Schoology, and find each one by the name shown on its card.

Catch-up / reteachFor: Need extra support
PLTW BI Mission File 1 Clinical Medicine & ER Innovation Overview
worksheet/handoutPosted in Schoology
Open in Schoology

Use this if you were absent, got stuck, or need another pass before you submit the lesson artifact.

Placement rationale

Matched ER presentation and physiology bridge by path:Biomedical-Innovations/Problem-1_Emergency-Room/1.1_Emergency-Room; keywords:emergency room, clinical. Score 142. Visibility: student-schoology (student-facing resource; link through Schoology rather than local path).

Use during lessonFor: Everyone
BI Project 2.1.1 Scientific Research Student Activity
worksheet/handoutPosted in Schoology
Open in Schoology

Open this when the class reaches this activity and use it to complete the required lesson artifact.

Placement rationale

Matched ER presentation and physiology bridge by path:Biomedical-Innovations/Problem-2_Human-Physiology/2.1_Human-Physiology; keywords:physiology. Score 134. Visibility: student-schoology (student-facing resource; link through Schoology rather than local path).

Use during lessonFor: Everyone
PLTW BI Activity 2.1.2 Science and the Media
worksheet/handoutPosted in Schoology
Open in Schoology

Open this when the class reaches this activity and use it to complete the required lesson artifact.

Placement rationale

Matched ER presentation and physiology bridge by path:Biomedical-Innovations/Problem-2_Human-Physiology/2.1_Human-Physiology; keywords:physiology. Score 134. Visibility: student-schoology (student-facing resource; link through Schoology rather than local path).

How to get there: open Clever and sign in with your Microsoft (district) account. Both myPLTW and Schoology are in Clever. Do the activity in myPLTW. Turn the work in on this site or hand it to Mr. Mendoza, because that is the step that counts as submitted. Schoology only shows your report-card grade later.

Check yourself · commit, then reveal

Claim ceiling for this check: The supplied lesson evidence can support an observation, pattern, classroom mechanism, or next-step decision about Physiology variables. It cannot by itself prove causation, establish a real clinical diagnosis, or justify action outside this classroom task.

Quick self-check · commit, then reveal

You test whether caffeine raises heart rate. Which is the independent variable and which is the dependent variable?

How sure are you?

Write an answer and pick a confidence to unlock the key.

Cumulative WebXam review · flash practice

Fast retrieval with instant answers, not the commit-then-reveal check above. Try each from memory first: write what you remember about the earlier units, then check yourself here.

Tap an answer to check it · nothing is recorded or graded
[Review: Designing a better ER: triage, patient flow, and stakeholder needs] A co-worker from another lab wants to use your microscope. What should you ask them to do first?
[Review: Finding the truth: credible sources, prior art, and needs assessment] After finding the experimental group had lower glucose than the placebo group, what is the next step?
[Review: Prototyping the ER: floor plans, process flow, and human factors] How should you properly prepare hydrochloric acid (HCl) for disposal?
You are measuring the rate that catalase breaks down hydrogen peroxide. What is the dependent variable?
Go further and get help
Where this leads: careers
What to do if you were absent
If YOU are absent

Today is individual work you can do from home: complete the same target above, then submit your Exit ticket.

Open the drop folder

Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

If MR. MENDOZA is absent

Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:

Khan Academy Scientific Method
How this is graded
For: Exit ticket: Problem 2 launch: chosen physiological measure, identified independent/dependent/controlled variables, and a testable hypothesis.
  • Complete
    Every required part of the artifact is present, nothing left blank.
  • Accurate
    The science and the data are correct and match the evidence.
  • Scientific reasoning
    You explain your claim with evidence and reasoning (CER), not just an answer.
  • Professional communication
    Clear, organized, labeled, and written the way a clinician or scientist would.
  • Submitted
    Turned in the right way, on the class site or handed to Mr. Mendoza in class, and confirmed. Not in Schoology: that is where the report-card grade appears later.