Period 6A-7B calendar

This class runs in two periods and they do not do the same lesson on the same day. You are reading the Period 6A-7B calendar, the one with John Carroll bioethics on Mondays.

Mon, Dec 14, 2026Fall (Semester 1) · Week 17Day 61 of 6480-min blockTight fit

Coating ratio CER

Essential question: What must we understand about Coating ratio CER to act on it?Enduring understanding: Reasoning from evidence about Coating ratio CER is how a clinician moves from an observation to a decision.

Do now

Design your own ratio trial, then write a CER recommending a coating ratio against the five-to-six-minute window.

DueTonight, 11:29 PM
Hand in
CER stating whether the prototype met its design goal, citing averaged trial data and variable-control evidence, explaining design strengths and flaws, proposing a specific iteration with a predicted result, and stating test-data limitations.
Where
Submit this on the class form named on this page. The form requires the student's district Microsoft sign-in. The thank-you page is the submission receipt. A physical handoff counts only when the day page names that route. Doing the activity in myPLTW does not count as submitted.

You get two school days for every day you were absent, so this deadline moves with you.

If the form offers you a saved draft, choose New draft. If the Assignment box comes up empty, type it exactly: Coating ratio CER

Where you are · this course
Unit 4.1 Innovation, Inc.: Engineering design, device/vessel model, CAD concept, prototype testing, disease prevention. Coating ratio CER ▸ Day 3
Day 61 of 64 this semester3 left before WebXam
🧬 Where you are · PLTW
Unit 4: Innovation, Inc. ▸ Lesson 4.1 Designing the Future"Activity 4.1.5 Drug Design Lab"
Counts toward: Biotechnology Research and Experiments (46.07% of the 072110 exam)
Every activity name and number was checked against your myPLTW course: Unit 1 against the PBS Teacher Guide on 2026-08-04, Units 2 to 4 against the full course crawl and the official PBS student files on 2026-08-05. Open this exact name in myPLTW (find it in Clever, Microsoft sign-in) so you never get lost.
Check the course before you open it. PLTW reuses the same numbers in different courses, so 3.2.2 in this class is not 3.2.2 in another Biomedical class. Match the course name and the lesson, not just the number. We write L for Lesson, A for Activity, Proj for Project and Prob for Problem, so you can tell them apart.
Today's driving question

Design your own ratio trial, then write a CER recommending a coating ratio against the five-to-six-minute window.

Today you'll be able to

Design your own ratio trial, then write a CER recommending a coating ratio against the five-to-six-minute window.

You've got it when
  • Change one variable at a time so a result can be attributed to the ratio.
  • Recommend a ratio against the window, not against the fastest time.
Due today · CER RequiredCER stating whether the prototype met its design goal, citing averaged trial data and variable-control evidence, explaining design strengths and flaws, proposing a specific iteration with a predicted result, and stating test-data limitations.
Do-Now · start these with your notes closed
  1. What do you already know about Coating ratio CER?
  2. What would you need to find out to answer today's question?
Do this · step by step
numbered so we can always find our place
  1. 1State the target precisely: intact through the stomach phase, then fully separated from the coverslip between five and six minutes.
  2. 2Choose which polymer ratios you will test and how many, and write down why.
  3. 3Write your of fully separated before you run anything, and how you will time it.
  4. 4Decide whether you will repeat each ratio, and how many times.
  5. 5Run the trials and record on the data sheet.
  6. 6Write the CER: your recommended ratio, the data that supports it, and the reasoning that connects them.
Interrupted or lost? If you were interrupted, reread the last line you wrote, then answer: which step am I on, and did I finish it? Start again from that step.
The story

What did this day actually feel like?

Frontier medicine ethics debate

ETHICS MONDAY The final Monday. Should biomedical research money go to extreme frontiers like space and undersea medicine, or to everyday care that helps more people now?

I argued for everyday care and lost ground on a point I had not considered: frontier research produces unexpected breakthroughs that come back to ordinary patients, and you cannot know in advance which ones.

The counterargument to my counterargument is that "it might pay off somehow" justifies any spending at all.

We ended without resolving it, which at this point is what I expect and no longer find frustrating.

John Carroll closed by asking us to name one position we had changed across the semester. Mine was genetic privacy. I came in certain and left genuinely unsure, and I think that is an improvement.

Turned in: exit ticket → Exit Tickets folder

Fiction. There is no such student. The lessons, labs and dates are the real planned course; the student, the classmates and the conversations are invented.

🛠 Get unstuck · pick your level

Need a running start
Two-minute running start: the one idea today depends on, before you touch Coating ratio CER.
On track
Work the posted parallel example, reasoning shown, then start your own case.
Stuck? Get unstuck
Stuck? Name where your thinking split from the example, then redo just that step.
Push me further
Push further: design a control or a test that would catch a wrong answer.

🔑 Today's words · 5

prototypeconstraintcriterionCADiteration
+3 more in the word bank

Tap a word in the lesson for a plain meaning and one example. Recycled into next week's Do-Now.

Print or open for todayActivity 4.1.5 Drug Design Lab

Check you have the right sheet: the top of it prints today's portal day, Coating ratio CER. The PLTW activity itself is in myPLTW and is not posted here.

Unit 4 extra creditNine items, any order, turn one in any day. Read the cover sheet first.Cover sheet (6 pages)See all nine
Today's study notebook
Designing a biomedical innovation: finding a real need, the design process, medical devices and sensors, and prototyping a solution.
Open the notebook
Watch first: today's 1-minute intro
Video overview
Where this fits
Tested on (Ohio WebXam)
Principles and Practice of Biomedical Technology · 072110
PLTW lesson
PBS · Lesson 4.1 Designing the Future
WebXam domain
Handling, Preparation, Storage and Disposal
Evidence to produce
CER
Lab / skill
PhET: simulations for engineering and physical testing
Do the work · 80-minute blockfirst 5 min = hook

💡 Big idea: This is the first task in the course where better is not more: a coating that opens at three minutes fails exactly as hard as one that opens at nine.

  1. 0-8 minReview Wednesday : confirm average performance and trial variability.
  2. 8-20 minWrite the claim: one sentence stating whether the prototype met its design goal.
  3. 20-42 minWrite evidence: cite average trial data, controlled variables, and one variability observation.
  4. 42-58 minWrite reasoning: link data to design strengths and flaws.
  5. 58-70 minWrite the iteration proposal (one variable to change, predicted outcome) and test-data limitations.
  6. 70-80 min: confirm claim addresses the design goal, data is cited specifically, iteration predicts a result.
Mr. Mendoza's 5-minute intro
  • You collected the data Wednesday; now you write the formal argument about what it means for the device design.
  • The claim must address the design goal directly: did the prototype meet the specification or not?
  • The iteration you propose is the most practically valuable part of this CER: it says what you would do next.
  • Your limitation should explain why the Wednesday data might not generalize to a real clinical use case.
Know by the end
  • A prototype evaluation CER claim states whether the device met the specified design goal, not whether it was 'good.'
  • Trial data is the primary evidence: average performance and trial-to-trial variability both belong in the evidence section.
  • An iteration proposal changes one variable based on the data; it should predict what the next trial result will be.
Open this PLTW section today

Unit 4.1 Innovation, Inc.: Engineering design, device/vessel model, CAD concept, prototype testing, disease prevention. · Coating ratio CER

Day 3 of this lesson. Open this exact section in myPLTW (find it in Clever, Microsoft sign-in), then do the work below.

Do this: Open myPLTW and find Lesson 4.1 Designing the Future, Activity 4.1.5 Drug Design Lab Part II, and use its analysis prompts as a writing scaffold.

Complete

Submit any platform prompts before shifting to independent CER writing.

How far to get

Platform prompts done in first 10 minutes; full CER submitted before end of period.

Upload as evidence

Submitted CER on the class site, or hand it to Mr. Mendoza in class is the primary evidence.

The official PLTW activity stays inside myPLTW. If myPLTW will not open, use F1 and E1-E3 on this page to complete today's local evidence decision, then make up the official activity when access returns. Submit this on the class form named on this page. The form requires the student's district Microsoft sign-in. The thank-you page is the submission receipt. A physical handoff counts only when the day page names that route. Doing the activity in myPLTW does not count as submitted.

Today's PLTW tracker · fill in and submit

Check things off as you work, then submit. This tells Mr. Mendoza how you're doing so he can help the class. It does not replace turning in your producible through the submission route shown below.

Use the code Mr. Mendoza gave you, not your name. Saved on this device.

Unit 4.1 Innovation, Inc.: Engineering design, device/vessel model, CAD concept, prototype testing, disease prevention.Day 3 of this projectSee the full week plan
Today's PLTW target

Unit 4.1 Innovation, Inc.: Engineering design, device/vessel model, CAD concept, prototype testing, disease prevention. · Coating ratio CER

Open myPLTW and find Lesson 4.1 Designing the Future, Activity 4.1.5 Drug Design Lab Part II, and use its analysis prompts as a writing scaffold.

Platform prompts done in first 10 minutes; full CER submitted before end of period.

This is how Mr. Mendoza sees the class keeping pace with PLTW. Be honest, it only helps if it is accurate.

1 · What you do today

🎯 Design your own ratio trial, then write a CER recommending a coating ratio against the five-to-six-minute window.

  • State the target precisely: intact through the stomach phase, then fully separated from the coverslip between five and six minutes.
  • Choose which polymer ratios you will test and how many, and write down why.
  • Write your of fully separated before you run anything, and how you will time it.
  • Decide whether you will repeat each ratio, and how many times.
  • Run the trials and record on the data sheet.
  • Write the CER: your recommended ratio, the data that supports it, and the reasoning that connects them.
2 · What you turn in

CER: CER stating whether the prototype met its design goal, citing averaged trial data and variable-control evidence, explaining design strengths and flaws, proposing a specific iteration with a predicted result, and stating test-data limitations.

Submit this on the class form named on this page. The form requires the student's district Microsoft sign-in. The thank-you page is the submission receipt. A physical handoff counts only when the day page names that route. Doing the activity in myPLTW does not count as submitted. Use the checklist just below and upload by 11:29 PM for full credit. Absent with an excused absence? You get two school days for every day you were absent, so this deadline moves with you.

3 · Who's doing what (team)
TaskWho
State the target precisely: intact through the stomach phase, then fully separated from the coverslip between five and six minutes._______
Choose which polymer ratios you will test and how many, and write down why._______
Write your of fully separated before you run anything, and how you will time it._______
Decide whether you will repeat each ratio, and how many times._______
Run the trials and record on the data sheet._______
Write the CER: your recommended ratio, the data that supports it, and the reasoning that connects them._______

Working solo? Put your own name in "Who" for every row.

4 · Words I can use correctly
5 · I'm successful today when I can…
  • Change one variable at a time so a result can be attributed to the ratio.
  • Recommend a ratio against the window, not against the fastest time.
6 · Reflection & next steps
Where are you today?0/8 checked
Pick your period and code first.
Your 4 steps today
  1. 1
    Do this
    Design your own ratio trial, then write a CER recommending a coating ratio against the five-to-six-minute window.
  2. 2
  3. 3
    Submit this
    CER: CER stating whether the prototype met its design goal, citing averaged trial data and variable-control evidence, explaining design strengths and flaws, proposing a specific iteration with a predicted result, and stating test-data limitations.
  4. 4
    Submit it here
    1. 1Open the form. It must say For students at the top: if it says For parents and guardians, press Back and pick I am the student.
    2. 2If it offers you a saved draft, choose New draft: an old draft brings back the old assignment.
    3. 3Sign in with your district Microsoft account, not a personal one.
    4. 4Check the Assignment box says today's assignment from this page, then pick your period and type your student ID, all nine digits.
    5. 5Attach your file and press Submit. The thank-you page is your receipt.
    Submit this on the class form named on this page. The form requires the student's district Microsoft sign-in. The thank-you page is the submission receipt. A physical handoff counts only when the day page names that route. Doing the activity in myPLTW does not count as submitted. Principles of Biomedical Technology (Principles of Biomedical Science) › Unit 4.1 Innovation, Inc.: Engineering design, device/vessel model, CAD concept, prototype testing, disease prevention. › CER
    Turn it in
Were you absent? Jump to the make-up plan
Learn it · deck, reading, and vocabulary
Socratic teaching slide deck

The deck carries the prior idea forward, lets you inspect an analogy, maps the rule to biology, and ends with the same evidence decision and exit ticket used on this page.

Generated from this lesson's canonical data with a red-team citation check.

Carry forward

An interval you skipped is data you cannot get back, so the discipline of the interval is what makes the run usable.

Daily take-home

This is the first task in the course where better is not more: a coating that opens at three minutes fails exactly as hard as one that opens at nine.

Inspect the analogy

A detective board holds observations, possible explanations, and one next question.

  1. Which notes are direct observations?
  2. Which notes are explanations?
  3. What new evidence would separate the explanations?
Rule

Keep observations separate from explanations, then collect the evidence that can distinguish the options.

Where it breaks

Biomedical investigations use controlled procedures and validated measurements, not intuition alone.

Map the analogy to biology
  • Board notes map to the signs, results and measurements you recorded.
  • Possible explanations map to the competing biological causes.
  • The next question maps to the test or observation that would separate them.
Read this first

Driving question: Design your own ratio trial, then write a CER recommending a coating ratio against the five-to-six-minute window.

What you already know: An interval you skipped is data you cannot get back, so the discipline of the interval is what makes the run usable.

New idea: This is the first task in the course where better is not more: a coating that opens at three minutes fails exactly as hard as one that opens at nine.

Visual or model: F1. F1. A lesson illustration or teaching diagram for Coating ratio CER. Use it with E1-E3; it is a model or context image, not experimental or patient data. What to notice: Use the labels and arrows in F1 to identify the relationship that supports Coating ratio CER.

  1. Observe or measure the relevant feature in coating ratio CER.
  2. Organize the observation with a stable evidence ID.
  3. Apply this rule: Keep observations separate from explanations, then collect the evidence that can distinguish the options.
  4. Choose the option the evidence supports and state the limit of the conclusion.

Real biomedical example: Design your own ratio trial, then write a CER recommending a coating ratio against the five-to-six-minute window.

What the evidence supports: E1-E3 and F1 support the daily take-home when the response meets the stated success criteria.

What it cannot prove: The package does not support claims beyond this lesson's or any real patient diagnosis.

Vocabulary:
  • prototype: Use the lesson context and glossary entry to explain prototype in your own words.
  • constraint: A limit or requirement that a design must work within, such as a budget, available time, materials, or rules.
  • criterion: A clear, agreed-upon standard or rule used to judge, compare, or decide between options.
  • CAD: Computer-aided design: software used to create precise digital models of objects, such as prosthetics or medical devices, before building them.
  • iteration: One repeated cycle of building, testing, and improving, where each pass refines the design or result based on what the last pass revealed.
  • : A small mesh tube placed inside a narrowed or blocked vessel or duct to hold it open and keep fluid flowing.
  • prevention: Actions taken to stop a disease or injury before it happens, such as vaccines, screenings, or healthy daily habits.
  • : A written outline of what will be tested, how, and what counts as success, used to guide an experiment or product check.

Use it now: Choose one decision option. Cite E1 and E3, then explain how the rule connects the evidence to your choice.

Go further, optional: The source links below are optional enrichment. Every fact required for today's local evidence decision appears in this lesson package.

Evidence set and decision
E1 · Source fact

A biomedical design advances when test evidence is compared with explicit user needs, criteria, constraints, risks, and failure modes, then used to justify a documented revision.

Limit: A classroom prototype, , presentation, or does not establish clinical , effectiveness, manufacturing quality, or regulatory clearance.

E2 · Teaching model

Keep observations separate from explanations, then collect the evidence that can distinguish the options.

Limit: Biomedical investigations use controlled procedures and validated measurements, not intuition alone.

E3 · Task criterion

Change one variable at a time so a result can be attributed to the ratio.

Limit: E3 defines the classroom product or success criterion. It is not independent scientific evidence and cannot justify a clinical or causal claim.

PLTW-PBT@P67-2026-12-14 · Simulated classroom evidence scenario

Your role: biomedical team member

Decision: Your team must decide what the evidence from coating ratio CER supports before submitting the claim-evidence-reasoning response named on the lesson page.

  • Keep the current design.
  • Revise the feature that misses a criterion.
  • Run one more fair test before choosing.

Response: State one choice, cite at least two evidence IDs, explain the rule that connects them, and add one limitation. Submit it as the claim-evidence-reasoning response.

Claim ceiling: Today's evidence supports a classroom claim about coating ratio CER. It cannot prove causation, diagnose a real patient, or justify action outside this room.

Composite case file · PLTW-PBT@P67-2026-12-14

Reason for review: Your team must decide what the evidence from coating ratio CER supports before submitting the claim-evidence-reasoning response named on the lesson page.

Context: Design your own ratio trial, then write a CER recommending a coating ratio against the five-to-six-minute window.

Timeline:
  • T1: State the target precisely: intact through the stomach phase, then fully separated from the coverslip between five and six minutes.
  • T2: Choose which polymer ratios you will test and how many, and write down why.
  • T3: Write your of fully separated before you run anything, and how you will time it.
  • T4: Decide whether you will repeat each ratio, and how many times.
  • T5: Run the trials and record on the data sheet.
  • T6: Write the CER: your recommended ratio, the data that supports it, and the reasoning that connects them.
Evidence records:
  • E1: A biomedical design advances when test evidence is compared with explicit user needs, criteria, constraints, risks, and failure modes, then used to justify a documented revision.
  • E2: Keep observations separate from explanations, then collect the evidence that can distinguish the options.
  • E3: Change one variable at a time so a result can be attributed to the ratio.

Measurements: Use only the measurements, units, graph, or counts supplied in today's task. No additional patient measurement is implied.

Figure finding: Teaching diagram for Coating ratio CER. Use the labels and arrows to identify the decision-relevant relationship. This is a teaching model, not patient or experimental data.

Uncertainty: This is a composite classroom scenario. Missing history, measurements, or confirmation tests remain unknown and limit the conclusion.

Math moment
Formula or setup

Mean = sum of values / number of values. Median = middle ordered value. Range = maximum - minimum.

Worked parallel example

For 2, 4, 4, and 10: mean = 20 / 4 = 5, median = 4, and range = 10 - 2 = 8.

Units and reasonableness

Mean, median, and range keep the measurement unit. Order the values before finding the median.

Try it with today's data

Calculate the requested summary for today's supplied values, then write what it reveals and what it hides.

Design record
Criteria
  • The solution must address the stated need in coating ratio CER.
  • The decision must be supported by E1-E3.
  • The final product must make the success criteria visible.
Constraints
  • Complete the work inside the 80-minute block.
  • Use only supplied or teacher-approved materials and evidence.
  • Do not trade , accessibility, or privacy for speed.
Tradeoff weights
  • and evidence quality: must pass before scoring other criteria.
  • User need and effectiveness: highest scored criterion.
  • Time, cost, and ease of use: compare only after and effectiveness pass.

Test evidence: For each option, record the E1-E3 result that supports or fails each criterion. Do not assign a score without a named observation.

Iteration log
  1. Version or option tested
  2. Criterion met or missed
  3. Evidence ID and result
  4. Revision made
  5. Reason for the revision
Decision record
  1. Need and user
  2. Criteria and constraints
  3. Chosen option and evidence
  4. Test result
  5. Revision and reason
Worked example · a parallel case (guides, does not reveal)
Non-answer evidence and reasoning scaffold
Completes: A blank structure for organizing the assigned response. It contains no claim, ranking, calculation, data interpretation, or recommendation from today's task.

1. Decision or claim I am testing: ____

2. Evidence ID and exact observation: ____

3. Second evidence ID and exact observation: ____

4. Rule that connects the evidence to my claim: ____

5. Strongest alternative or tradeoff: ____

6. Limitation or missing evidence that controls my confidence: ____

7. Revision I would make if the missing evidence changed: ____

Why this matters

This model shows the level of evidence and organization needed to complete: A blank structure for organizing the assigned response. It contains no claim, ranking, calculation, data interpretation, or recommendation from today's task.

Build yours step by step
  1. Write one defensible claim.
  2. Choose specific evidence that supports the claim.
  3. Explain the scientific rule that connects the evidence to the claim.
Change it for a new task

Keep the structure. Replace the question, facts, measurements, and evidence. Then recheck units, vocabulary, and whether the conclusion goes beyond the evidence.

Also due today: Submit your CER on the class site, or hand it to Mr. Mendoza in class before end of period.

See the full worked example
Portal terms
CER:
Claim, Evidence, Reasoning: make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure, the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities. Find it in Clever with your Microsoft sign-in, right next to Schoology.
This unit's vocabulary
prototype(Computer-Aided Design)

Tap the speaker to hear a term. Add two of these to your notebook glossary with a definition and an example in your own words.

Build your vocabulary · optional, for extra credit

Pick just 2 or 3 words from today and make them yours: write what each one means in your own words, name the context clue or evidence that helped, then give one example from what you actually did in Coating ratio CER. Try your own words first; the glossary is there if you get stuck. This is voluntary and counts as extra credit, so keep it short.

prototype
constraint
criterion
CAD
iteration
stent

Saved on this device. Show Mr. Mendoza or add these to your notebook glossary to claim the extra credit.

Resources & readings

Hand-picked readings and interactives for this lesson, from authoritative open organizations and PLTW's own public course outline.

Check yourself · commit, then reveal

Claim ceiling for this check: Today's evidence supports a classroom claim about coating ratio CER. It cannot prove causation, diagnose a real patient, or justify action outside this room.

WebXam-style practice
Tap an answer to check it · nothing is recorded or graded
A study tests if different wavelengths of light affect the rate of photosynthesis. What is the independent variable?
A researcher tests a new vitamin on plant height; one group gets the vitamin and the other plain water. What is the plain-water group?
You test the effect of varying chemical concentrations on plant growth. What is the dependent variable?
When testing a prototype device, why should you change only one design variable at a time between trials?
Cumulative WebXam review · flash practice

Fast retrieval with instant answers, not the commit-then-reveal check above. Try each from memory first: write what you remember about the earlier units, then check yourself here.

Tap an answer to check it · nothing is recorded or graded
[Review: Outbreak Evidence: line lists, epidemic curves, and identifying the agent] To confirm the causative agent of a foodborne outbreak, what evidence is most definitive?
[Review: Emergency Response: assessment, triage, and stabilization] A solution at pH 2 must be made safe for disposal. What target pH should you aim for?
[Review: Medical Surge: mobile care and a public-health communication app] Why must surveillance data shared across a hospital protect patient privacy?
A study tests if different wavelengths of light affect the rate of photosynthesis. What is the independent variable?
Go further and get help
🔬 Pre-lab simulation

Run this before you touch the bench. It is built from the real lab procedure, so the decisions you make here are the ones you will make with the equipment in your hands.

It Was Inert in the Beaker
Open the simulation →
Where this leads: careers
What to do if you were absent
If YOU are absent

Today is individual work you can do from home: complete the same target above, then submit your CER.

Turn it in

Submit this on the class form named on this page. The form requires the student's district Microsoft sign-in. The thank-you page is the submission receipt. A physical handoff counts only when the day page names that route. Doing the activity in myPLTW does not count as submitted.

If MR. MENDOZA is absent

Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:

PhET: simulations for engineering and physical testing
Optional extra credit (async)

You've passed Unit 2, so the optional extra-credit track is open. Complete reserved-unit work from home, including virtual labs, for extra credit. Each item shows its correct submission route.

Open the extra-credit track
How this is graded
For: CER: CER stating whether the prototype met its design goal, citing averaged trial data and variable-control evidence, explaining design strengths and flaws, proposing a specific iteration with a predicted result, and stating test-data limitations.
  • Complete
    Every required part of the artifact is present, nothing left blank.
  • Accurate
    The science and the data are correct and match the evidence.
  • Scientific reasoning
    You explain your claim with evidence and reasoning (CER), not just an answer.
  • Professional communication
    Clear, organized, labeled, and written the way a clinician or scientist would.
  • Submitted
    Turned in through the one route named under Submit here and confirmed by the form receipt or the named physical handoff. Not in Schoology: that is where the report-card grade appears later.