Semester 1 (Fall) · Week 5 (teaching week 5 of 17)Sep 21–25

Unit 1.1 to 1.2: Experimental design in evidence testing; transition to autopsy evidence and biomolecules.

Your PLTW coursework: Principles of Biomedical Science ▸ Unit 1: Medical Investigation ▸ Lesson 1.1 Investigating the Scene ▸ "Activity 1.1.4 Blood Evidence", "Activity 1.1.5 DNA Evidence", "Activity 1.1.6 DNA Analysis", "Activity 1.2.3 Forensic Toxicology"

What to do if absent
Color keyLearn firstGet orientedDo the workLab daySafety netCheck yourself
Portal terms
CER:
Claim, Evidence, Reasoning: make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure, the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities. Find it in Clever with your Microsoft sign-in, right next to Schoology.
Learn first

Week overview - From Scene to Lab: designing evidence tests and meeting biomolecules

Sep 21–25

Design a controlled test for a piece of evidence, then connect that thinking to evidence and the biomolecules a toxicology screen looks for in .

Week arc
  1. 1Review your Unit 1.1 evidence log and pick one question that a lab test could answer.
  2. 2Write a testable and identify the , , and control.
  3. 3Predict your results and describe the you would use to record them.
  4. 4Read how a toxicology screen detects biomolecules in and list the groups involved.
  5. 5Connect and to the kinds of evidence an collects.
  6. 6Write a two-sentence claim-evidence-reasoning statement linking your test design to a possible conclusion.
By week end
  • • You can write a testable with clearly named variables and a control.
  • • You can describe a that fits your experiment.
  • • You can name the major groups a toxicology screen examines.
The plan

Daily lessons this week

Open any day for its full lesson, the work due that day, and guided notes.

MondayMon, Sep 21
Analyze tox results

Match matrix and panel sheet

TuesdayTue, Sep 22
Ethics of autopsy

Ethics review-board worksheet

WednesdayWed, Sep 23
Body systems and tissues

Time-of-death worksheet

ThursdayThu, Sep 24
JCU bioethics 1: Should ELISA testing be mandatory?

One claim, evidence, reasoning response built from your debate worksheet: the side you argued, your three strongest arguments, the opposing point you answered, and where you stand now

FridayFri, Sep 25
Week 5 review: the profile, the clock, and the two errors

Week 5 Review Record, Parts A to E in one document: three STR calls with limits, a time-of-death window with its assumptions, the four labeled outcome cells with one example each, three ceiling sentences, and the pass with one open question.

Get oriented

Quick intro to the week

  • Good evidence testing is just good experimental design, so today you turn a hunch into a fair test.
  • Today's goal: design a controlled evidence test and learn why biomolecules in are the next layer of the case.
  • Monday's bioethics debate ties in: should investigators be allowed to run every possible test on a sample, or only the ones the case needs?
  • Your graded experimental design and mini-CER are submitted on the class site.
Do the work

Your PLTW coursework this week

Do this: Bridge the PLTW PBS Unit 1.1 to 1.2 benchmark by designing a controlled evidence test and introducing and toxicology evidence in the online shell.

Know when done
  • • A fair test changes one and measures one against a control.
  • • Biomolecules are the macromolecules (carbohydrates, lipids, proteins, nucleic acids) that toxicology screens detect.
  • • and are separate determinations drawn from evidence.
Be able to do
  • • Write a testable and identify its variables and control.
  • • Plan a that matches an experiment's variables.

📋 PLTW evidence due Friday: completed Unit 1.1 to 1.2 experimental design with variables, , and a mini-CER.

All PLTW activities are completed inside the PLTW course environment: this page only gives direction.

The plan

This week's PLTW tracker

Use this chart to keep your place. Nothing on it is turned in through the portal.

DayWorkTurn in
Monday · Mon, Sep 21Analyze tox resultsMatch matrix and panel sheet
Tuesday · Tue, Sep 22Ethics of autopsyEthics review-board worksheet
Wednesday · Wed, Sep 23Body systems and tissuesTime-of-death worksheet
Thursday · Thu, Sep 24JCU bioethics 1: Should ELISA testing be mandatory?One claim, evidence, reasoning response built from your debate worksheet: the side you argued, your three strongest arguments, the opposing point you answered, and where you stand now
Friday · Fri, Sep 25Week 5 review: the profile, the clock, and the two errorsWeek 5 Review Record, Parts A to E in one document: three STR calls with limits, a time-of-death window with its assumptions, the four labeled outcome cells with one example each, three ceiling sentences, and the 6 Rs pass with one open question.
  • First class day: bioethical debate (Monday is a closure)
  • T: teacher background notes + PLTW launch task
  • W: lab / data or model work
  • Th: analysis / CER or design revision
  • F: submit tracker + weekly evidence

Turn in: Unit 1.1 to 1.2: Experimental design in evidence testing; transition to autopsy evidence and biomolecules. weekly work due Trace/biometric data analysis plus mini-CER.

Go to Schoology to turn this in.

Submit one PDF. Schoology attaches your name to your upload; on the page itself, write your period and code. Name the file: FirstName LastName - Assignment Title - YYYY-MM-DD.pdf.

Open Schoology PDF upload help

If you cannot get in, see Mr. Mendoza. Do not skip the work.

The week, drawn

3 panels from the illustrated semester.

Fiction. There is no such student. The lessons, labs and dates are the real planned course; the student, the classmates and the conversations are invented.

Safety net

What to do when absent

If YOU are absent

Most days, this class is your PLTW coursework: and PLTW is online and individual. So being out usually just means doing exactly what we did in class, from home.

Open Clever, then myPLTW

Sign in to Clever with your district Microsoft account to open Schoology or myPLTW. Follow today's posted steps. If myPLTW will not open, use the posted alternative and tell Mr. Mendoza. Turn in your completed work through the Schoology assignment.

Was today a lab or a group activity?

You can't do those from home: do this instead: Teacher-posted data/model packet, same objective. Supplemental: Khan: biomolecules; Khan: macromolecules.

If MR. MENDOZA is absent

Class still runs. A substitute will post today's plan: complete the online activity above; it's built to be self-guided. Need the concept taught without a teacher? Use this authoritative explainer:

Khan Academy: macromolecules
Words

Vocabulary

/tok-sih-KOL-uh-jee/
Explore

Resources & readings

Hand-picked readings and interactives for this lesson, from authoritative open organizations and PLTW's own public course outline.

Aligned to

Standards this week

• Principles & Practice of Biomedical Technology 072110 · 5.8 Biotechnology Research and Experiments
• NGSS science & engineering practices: planning investigations, analyzing data, argument from evidence
Check yourself

WebXam practice

Tap an answer to check it · nothing is recorded or graded
You are measuring the rate that catalase breaks down hydrogen peroxide. What is the dependent variable?
You test how diet impacts joint inflammation by giving mice regular versus special diets. What is the independent variable?
In the arthritis diet experiment, what serves as the control?
A researcher measures the zone of inhibition created by different mouthwashes. What is the dependent variable?