Fri, Apr 9, 2027Spring (Semester 2) · Week 12Day 38 of 5780-min blockTight fit

Research design and poster plan

Essential question: What makes a strong enough to build an entire investigation on?Enduring understanding: A precise, testable question decides the quality of every result that follows, because you cannot measure your way out of a vague starting point.

Safety gate · before any work

  • Wear the required PPE, keep the bench clear, handle equipment only as directed, and know where the eyewash, sink, and spill kit are before you start.
  • Human samples and data stay private: label with a code, never a name, and dispose of materials in the correct waste container, then wash your hands.

Do now

Students will design a C. elegans investigation and plan a research poster as a project team.

DueTonight, 11:29 PM
Hand in
Team research design plan: testable question, defined variables, target sample size, poster section outline, and assigned member roles.
Where
Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

You get two school days for every day you were absent, so this deadline moves with you.

Where you are · this course
Unit 2.2 Research Model: Model organisms, C. elegans, neurotransmitters/hormones, scientific literature, research poster. Research design and poster plan ▸ Day 3
Day 38 of 57 this semester19 left before WebXam
🧬 Where you are · PLTW
Human Body SystemsUnit 2: Research Ready ▸ Lesson 2.3 Challenge Accepted"Problem 2.3.1 Challenge Accepted (C. elegans research)"
Activity names confirmed from PLTW's published HBS career-connections and Mr. Mendoza's licensed updated-HBS materials. Mr. Mendoza will confirm the exact numbering in myPLTW once the course shell opens.
Today's driving question

Can your team turn "do worms like sugar?" into a question specific enough that another team could run it and get comparable data?

Today you'll be able to

Students will design a C. elegans investigation and plan a research poster as a project team.

You've got it when
  • Team produces a testable question with defined variables.
  • Poster plan assigns clear roles and sections.
Due today · Pre-lab RequiredTeam research design plan: testable question, defined variables, target , poster section outline, and assigned member roles.
Do-Now · start these with your notes closed
  1. Rewrite this vague question to be testable: "Is caffeine bad for worms?"
  2. Name one job (role) a research team needs filled so a project actually gets finished.
Do this · step by step
numbered so we can always find our place
  1. 1Review the components of a strong .
  2. 2As a team, draft a testable question about C. elegans.
  3. 3Define your variables, controls, and target .
  4. 4Outline the poster sections you will need.
  5. 5Assign each team member a poster responsibility.
Interrupted or lost? Lost your place? Confirm your team has a testable question written (organism, variable, measurable outcome), then move to defining your variables, setting a target , outlining poster sections, and assigning each person a poster job.
The story

What did this day actually feel like?

Research design and poster plan

TEAM DESIGN Teams writing an actual research design: testable question, defined variables, target sample size.

We spent most of the period on the question, which felt like stalling and was not. Our first version could not have been answered by any experiment we could run. Narrowing it until it was actually testable was the work.

Turned in: team research design plan → recorded in Class Records

Fiction. There is no such student. The lessons, labs and dates are the real planned course; the student, the classmates and the conversations are invented.

The comic

The same day, drawn.

Drawing, panel 56: Research design and poster plan.

Teams writing an actual research design: testable question, defined variables, target sample size.

CLASSMATE

Our sample size is optimistic. This paper used four times as many.

Panel 56Research design and poster plan · 2027-04-09
Read week 11, 5 panels

Fiction. There is no such student. The lessons, labs and dates are the real planned course; the student, the classmates and the conversations are invented.

🛠 Get unstuck · pick your level

Run the lab
Draft your team's question, then stress-test it: could a different team read it and run the exact same experiment? If not, tighten the organism, variable, or outcome until they could.
Absent? Async catch-up
If you missed team day, use the project thread to adopt your group's question and claim one poster section so you are ready to contribute when you return.

Lab day: Tier 1 is the whole class at the bench. No extension today.

🔑 Today's words · 5

model organismC. elegansassayliteraturevariable
+2 more in the word bank

Tap a word in the lesson for a plain meaning and one example. Recycled into next week's Do-Now.

Today's study notebook
Variables, controls, and the research model behind a sound scientific investigation.
Open the notebook
Watch first: today's 1-minute intro
Audio overviewVideo overviewMind mapStudy guideFlashcardsQuizData table
Where this fits
Tested on (Ohio WebXam)
Human Anatomy and Physiology · 072040 (likely, pending confirmation)
PLTW lesson
HBS · Lesson 2.3 Challenge Accepted
WebXam domain
Human Body Form, Function, and Pathophysiology
Evidence to produce
Pre-lab
Do the work · 80-minute blockfirst 5 min = hook

💡 Big idea: A testable question names the organism, variable, and outcome, so that the entire investigation produces data other scientists can interpret and compare.

  1. 0-10Review: what makes a testable? (good vs. bad examples)
  2. 10-25Team drafts testable question; teacher circulates and provides feedback
  3. 25-42Define independent, dependent, and controlled variables; set target
  4. 42-58Outline poster sections: question, background, methods, results, conclusion
  5. 58-70Assign each team member one poster section; note responsibilities
  6. 70-80Share design plan with another team for quick feedback; submit plan
Mr. Mendoza's 5-minute intro
  • Scientists do not start experiments randomly; they start with a precise, testable question.
  • Today your team will write that question for your C. elegans investigation.
  • You will also plan your research poster so you know exactly what evidence you need to collect.
  • Good planning now means less confusion on lab day.
Know by the end
  • A testable question specifies the organism, variable, and measurable outcome.
  • A research poster communicates method, data, and conclusions in a standardized scientific format.
  • Team role assignment ensures accountability and mirrors how biomedical research teams operate.
Open this PLTW section today

Unit 2.2 Research Model: Model organisms, C. elegans, neurotransmitters/hormones, scientific literature, research poster. · Research design and poster plan

Day 3 of this lesson. Open this exact section in myPLTW (find it in Clever, Microsoft sign-in), then do the work below.

Do this: Find and complete the design-planning or team-project prompt in myPLTW that corresponds to today's C. elegans investigation design; finish it after your team drafts the testable question.

Complete

Mark the design-planning activity complete in myPLTW after submitting your team research plan.

How far to get

Variables task is done; today the design-planning task should show complete.

Upload as evidence

Note or screenshot of completion status for your tracker.

The official PLTW activity stays inside myPLTW. If myPLTW will not open, use F1 and E1-E3 on this page to complete today's local evidence decision, then make up the official activity when access returns. Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

Today's PLTW tracker · fill in and submit

Check things off as you work, then submit. This tells Mr. Mendoza how you're doing so he can help the class. It does not replace turning in your producible through the submission route shown below.

Use the code Mr. Mendoza gave you, not your name. Saved on this device.

Unit 2.2 Research Model: Model organisms, C. elegans, neurotransmitters/hormones, scientific literature, research poster.Day 3 of this projectSee the full week plan
Today's PLTW target

Unit 2.2 Research Model: Model organisms, C. elegans, neurotransmitters/hormones, scientific literature, research poster. · Research design and poster plan

Find and complete the design-planning or team-project prompt in myPLTW that corresponds to today's C. elegans investigation design; finish it after your team drafts the testable question.

Variables task is done; today the design-planning task should show complete.

This is how Mr. Mendoza sees the class keeping pace with PLTW. Be honest, it only helps if it is accurate.

1 · What you do today

🎯 Students will design a C. elegans investigation and plan a research poster as a project team.

  • Review the components of a strong .
  • As a team, draft a testable question about C. elegans.
  • Define your variables, controls, and target .
  • Outline the poster sections you will need.
  • Assign each team member a poster responsibility.
2 · What you turn in

Pre-lab: Team research design plan: testable question, defined variables, target , poster section outline, and assigned member roles.

Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not. Use the checklist just below and upload by 11:29 PM for full credit. Absent with an excused absence? You get two school days for every day you were absent, so this deadline moves with you.

3 · Who's doing what (team)
TaskWho
Review the components of a strong ._______
As a team, draft a testable question about C. elegans._______
Define your variables, controls, and target ._______
Outline the poster sections you will need._______
Assign each team member a poster responsibility._______

Working solo? Put your own name in "Who" for every row.

4 · Words I can use correctly
5 · I'm successful today when I can…
  • Team produces a testable question with defined variables.
  • Poster plan assigns clear roles and sections.
6 · Reflection & next steps
Where are you today?0/7 checked
Pick your period and code first.
Your 4 steps today
  1. 1
    Do this
    Students will design a C. elegans investigation and plan a research poster as a project team.
  2. 2
  3. 3
    Submit this
    Pre-lab: Team research design plan: testable question, defined variables, target sample size, poster section outline, and assigned member roles.
  4. 4
    Submit it here
    1. 1Open the drop folder.
    2. 2Sign in with your district Microsoft account, not a personal one.
    3. 3Upload the file, named Lastname_Firstname__Assignment Title.
    4. 4Your own upload panel says Uploaded with a green check: that is your receipt.
    Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not. Human Anatomy & Physiology (Human Body Systems) › Unit 2.2 Research Model: Model organisms, C. elegans, neurotransmitters/hormones, scientific literature, research poster. › Pre-lab
    Open the drop folder
Were you absent? Jump to the make-up plan
Learn it · deck, reading, and vocabulary
Socratic teaching slide deck

The deck carries the prior idea forward, lets you inspect an analogy, maps the rule to biology, and ends with the same evidence decision and exit ticket used on this page.

Generated from this lesson's canonical data with a red-team citation check.

Carry forward

A controlled experiment changes one variable and holds the rest constant, so that any change in the result can be attributed to that single cause.

Daily take-home

A testable question names the organism, variable, and outcome, so that the entire investigation produces data other scientists can interpret and compare.

Inspect the analogy

A bridge prototype is tested against a load limit, cost limit, and user need before revision.

  1. Which requirement is a criterion?
  2. Which limit is a constraint?
  3. What test result should trigger a redesign?
Rule

A design improves when evidence is compared with explicit criteria and constraints.

Where it breaks

Biomedical designs also require , ethics, and biological validation beyond a physical prototype test.

Map the analogy to biology
  • Bridge requirements map to design criteria.
  • Load results map to E1-E3.
  • Revision maps to the next evidence-based iteration.
Read this first

Driving question: Can your team turn "do worms like sugar?" into a question specific enough that another team could run it and get comparable data?

What you already know: A controlled experiment changes one variable and holds the rest constant, so that any change in the result can be attributed to that single cause.

New idea: A testable question names the organism, variable, and outcome, so that the entire investigation produces data other scientists can interpret and compare.

Visual or model: F1. F1. A lesson illustration or teaching diagram for Research design and poster plan. Use it with E1-E3; it is a model or context image, not experimental or patient data. What to notice: Trace the labeled structure, movement, or system relationship that connects form to function.

  1. Observe or measure the relevant feature in Research design and poster plan.
  2. Organize the observation with a stable evidence ID.
  3. Apply this rule: A design improves when evidence is compared with explicit criteria and constraints.
  4. Choose the option the evidence supports and state the limit of the conclusion.

Real biomedical example: Can your team turn "do worms like sugar?" into a question specific enough that another team could run it and get comparable data?

What the evidence supports: E1-E3 and F1 support the daily take-home when the response meets the stated success criteria.

What it cannot prove: The package does not support claims beyond this lesson's or any real patient diagnosis.

Vocabulary:
  • : A species, such as zebrafish or mouse, studied because its biology is similar enough to ours to teach us about human development and disease.
  • C. elegans: Use the lesson context and glossary entry to explain C. elegans in your own words.
  • : A that measures the presence, amount, or activity of a target substance such as a , , or chemical in a sample.
  • literature: The body of published research articles and reports on a topic that scientists read to learn what is already known before doing new work.
  • variable: Any factor in an experiment that can change or be changed, including what you test, what you measure, and what you hold steady.
  • control: The comparison condition that isolates the effect of the variable being tested by keeping everything else the same.
  • : The number of subjects or observations in a study; larger samples give more reliable results and reduce the role of chance.

Use it now: Choose one decision option. Cite E1 and E3, then explain how the rule connects the evidence to your choice.

Go further, optional: The source links below are optional enrichment. Every fact required for today's local evidence decision appears in this lesson package.

Evidence set and decision
E1 · Observation

A testable question specifies the organism, variable, and measurable outcome.

Limit: E1 supplies context or an observation; it does not by itself establish the explanation.

E2 · Mechanism

A testable question names the organism, variable, and outcome, so that the entire investigation produces data other scientists can interpret and compare.

Limit: E2 is a teaching statement or comparison and must be checked against the task evidence.

E3 · Result

Team produces a testable question with defined variables.

Limit: E3 supports only the result or product criterion named here; it cannot justify a broader clinical or causal claim.

PLTW-HAP-2027-04-09 · Simulated classroom evidence scenario

Your role: anatomy and physiology consultant

Decision: Your team must decide what the evidence from Research design and poster plan supports before submitting the pre-lab readiness record named on the lesson page.

  • Keep the current design.
  • Revise the feature that misses a criterion.
  • Run one more fair test before choosing.

Response: State one choice, cite at least two evidence IDs, explain the rule that connects them, and add one limitation. Submit it as the pre-lab readiness record.

Claim ceiling: The supplied lesson evidence can support an observation, pattern, classroom mechanism, or next-step decision about Research design and poster plan. It cannot by itself prove causation, establish a real clinical diagnosis, or justify action outside this classroom task.

Math moment
Formula or setup

Mean = sum of values / number of values. Median = middle ordered value. Range = maximum - minimum.

Worked parallel example

For 2, 4, 4, and 10: mean = 20 / 4 = 5, median = 4, and range = 10 - 2 = 8.

Units and reasonableness

Mean, median, and range keep the measurement unit. Order the values before finding the median.

Try it with today's data

Calculate the requested summary for today's supplied values, then write what it reveals and what it hides.

Design record
Criteria
  • The solution must address the stated need in Research design and poster plan.
  • The decision must be supported by E1-E3.
  • The final product must make the success criteria visible.
Constraints
  • Complete the work inside the 80-minute block.
  • Use only supplied or teacher-approved materials and evidence.
  • Do not trade , accessibility, or privacy for speed.
Tradeoff weights
  • and evidence quality: must pass before scoring other criteria.
  • User need and effectiveness: highest scored criterion.
  • Time, cost, and ease of use: compare only after and effectiveness pass.

Test evidence: For each option, record the E1-E3 result that supports or fails each criterion. Do not assign a score without a named observation.

Iteration log
  1. Version or option tested
  2. Criterion met or missed
  3. Evidence ID and result
  4. Revision made
  5. Reason for the revision
Decision record
  1. Need and user
  2. Criteria and constraints
  3. Chosen option and evidence
  4. Test result
  5. Revision and reason
Watch the trap

Students often think Students often think a good is one that sounds impressive or covers a big topic.. The trap: Big and impressive is usually untestable. A strong question is narrow on purpose: it names the organism, the one variable you change, and the exact outcome you will measure, because that is what makes it runnable and comparable.

Worked example · a parallel case (guides, does not reveal)
Team research design and poster plan
Completes: A team research-design plan: a testable question about C. elegans, defined variables, a target sample size, a poster section outline, and assigned member roles.

Testable question: Does increasing copper concentration in the water (0, 5, 10 ppm) decrease the movement speed of C. elegans measured as body bends per minute?

Variables:

  • Independent: copper concentration (0, 5, 10 ppm).
  • Dependent: body bends per minute.
  • Controlled: temperature, food, worm age, dish size, timing.

Target sample size: at least 10 worms per concentration, 3 trials each, to make the average reliable.

Poster section outline: Title and question, Background, Methods, Data (table and graph), Conclusion, Sources.

Roles:

  • Maria: Methods and data table.
  • Sample teammate B: Background and sources.
  • Sample teammate C: Graph and conclusion.
  • Sample teammate D: Layout and title block.
Why this matters

This model shows the level of evidence and organization needed to complete: A team research-design plan: a testable question about C. elegans, defined variables, a target sample size, a poster section outline, and assigned member roles.

Build yours step by step
  1. Identify the purpose, hazards, and required controls.
  2. Write the procedure in a usable order.
  3. Confirm materials, measurements, and waste handling before starting.
Change it for a new task

Keep the structure. Replace the question, facts, measurements, and evidence. Then recheck units, vocabulary, and whether the conclusion goes beyond the evidence.

Also due today: Submit your team design plan on the class site, or hand it to Mr. Mendoza in class.

See the full worked example
Portal terms
CER:
Claim, Evidence, Reasoning: make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure, the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities. Find it in Clever with your Microsoft sign-in, right next to Schoology.
This unit's vocabulary
C. elegans

Tap the speaker to hear a term. Add two of these to your notebook glossary with a definition and an example in your own words.

Build your vocabulary · optional, for extra credit

Pick just 2 or 3 words from today and make them yours: write what each one means in your own words, name the context clue or evidence that helped, then give one example from what you actually did in Research design and poster plan. Try your own words first; the glossary is there if you get stuck. This is voluntary and counts as extra credit, so keep it short.

model organism
C. elegans
assay
literature
variable
control

Saved on this device. Show Mr. Mendoza or add these to your notebook glossary to claim the extra credit.

Resources & readings

Hand-picked readings, videos, and interactives for this lesson, all free and from authoritative open organizations (NIH, CDC, OpenStax, Khan Academy, PhET, HHMI, and more).

Unit notebook (fillable)

A fillable, Cornell-style notebook for Unit 2: Research Ready. Type your notes, cues, and summaries right in the PDF, or print it and write by hand. Each lesson page has a cue column, a notes column, and a summary box, plus dated lab-record pages you can turn in.

HBS Unit 2 notebook: Research Ready Fillable PDFCornell notes + lab recordsOpen
Resources & readings

Vetted readings and references for this unit. Use them to prepare, to catch up if you were absent, or to go deeper on today's target.

Check yourself · commit, then reveal

Claim ceiling for this check: The supplied lesson evidence can support an observation, pattern, classroom mechanism, or next-step decision about Research design and poster plan. It cannot by itself prove causation, establish a real clinical diagnosis, or justify action outside this classroom task.

Quick self-check · commit, then reveal

Turn this into a strong, testable research question about C. elegans: "Does the environment change worms?" Your version must name the organism, the variable you change, and what you will measure.

How sure are you?

Write an answer and pick a confidence to unlock the key.

Cumulative WebXam review · flash practice

Fast retrieval with instant answers, not the commit-then-reveal check above. Try each from memory first: write what you remember about the earlier units, then check yourself here.

Tap an answer to check it · nothing is recorded or graded
[Review: Getting Nervous: the brain, neurons, and how signals travel] Which brain region is primarily responsible for coordinating balance and fine motor movements?
[Review: Reflexes: reaction time, signaling, and a patient diagnosis challenge] Why might a depressant drug increase a person's reaction time in a reflex test?
[Review: Everything Endocrine: hormones, feedback loops, and the blood-sugar model] Which gland releases glucagon when blood sugar falls too low?
Why is the roundworm C. elegans frequently used as a model organism in biological research?
Go further and get help
Lab · prepare, conduct, complete
1Prepare
Pre-lab pass · clear all six to go to the bench
0/6

I can name the procedure's purpose and the evidence I will record. I can identify each named hazard and the control that reduces it: Wear the required PPE, keep the bench clear, handle equipment only as directed, and know where the eyewash, sink, and spill kit are before you start. My data table is ready before materials are handled.

Finish the checklist before you handle any material.

Safety · specific to today's hazards
  • Wear the required PPE, keep the bench clear, handle equipment only as directed, and know where the eyewash, sink, and spill kit are before you start.
  • Human samples and data stay private: label with a code, never a name, and dispose of materials in the correct waste container, then wash your hands.
Review Lab Safety (rules, PPE, SDS, emergencies) and check your contract + test
2Conduct (Argument-Driven Inquiry)
  1. 1Before materials are handled, identify the purpose, variables or comparison, controls, measurement units, and stop-work condition.
  2. 2Review the components of a strong research question.
  3. 3As a team, draft a testable question about C. elegans.
  4. 4Define your variables, controls, and target sample size.
  5. 5Outline the poster sections you will need.
  6. 6Assign each team member a poster responsibility.
  7. 7Record each result in the prepared table before interpreting it. Mark missing, repeated, or invalid results truthfully.
  8. 8Complete the named cleanup and waste route, remove PPE safely, wash hands when required, and confirm the station is ready for the next group.
Prepare this data table before materials are handled
Trial or sample IDIndependent conditionMeasured result with unitsObservation before interpretationQuality-control note
     
     
     
3Complete
Argue from your evidence, then compare what you predicted to what happened. Error analysis names a specific method limit, never "human error".
You predicted

Before the procedure, predict the result and cite the rule behind the prediction.

What actually happened

After the procedure, compare the result with the prediction and name one limitation or source of uncertainty.

Your lab report is graded on the rubric below, with extra weight on error analysis and method.
Where this leads: careers
What to do if you were absent
Today was a project: do this instead

With your team, finalize a , variables, and a poster section outline with assigned roles.

HHMI BioInteractive (preview; use assigned fallback if blocked)

Then submit your Pre-lab. Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

If MR. MENDOZA is absent

Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:

Khan Academy: The science of biology (experimental design)
Optional extra credit (async)

You've passed Unit 2, so the optional extra-credit track is open. Complete reserved-unit work from home, including virtual labs, for extra credit. Each item shows its correct submission route.

Open the extra-credit track
How this is graded
For: Pre-lab: Team research design plan: testable question, defined variables, target sample size, poster section outline, and assigned member roles.
  • Complete
    Every required part of the artifact is present, nothing left blank.
  • Accurate
    The science and the data are correct and match the evidence.
  • Scientific reasoning
    You explain your claim with evidence and reasoning (CER), not just an answer.
  • Professional communication
    Clear, organized, labeled, and written the way a clinician or scientist would.
  • Submitted
    Turned in the right way, on the class site or handed to Mr. Mendoza in class, and confirmed. Not in Schoology: that is where the report-card grade appears later.
  • Error analysis and method · counts double
    Name a specific limit of the method and how it moved your result, and compare what you predicted to what happened. "Human error" does not count; say what about the procedure or instrument caused it.