Mon, Apr 12, 2027Spring (Semester 2) · Week 13Day 52 of 7080-min block

Hypothesis and protocol

Today's target

Students will write a hypothesis and protocol for a C. elegans heavy-metal investigation using teacher notes and the PLTW online task.

Due today · Pre-lab Required

Written if-then hypothesis, complete materials list, step-by-step procedure, and at least one safety consideration with rationale for the C. elegans heavy-metal investigation.

Your 4 steps today
  1. 1
    Do this
    Students will write a hypothesis and protocol for a C. elegans heavy-metal investigation using teacher notes and the PLTW online task.
  2. 2
  3. 3
    Submit this
    Pre-lab: Written if-then hypothesis, complete materials list, step-by-step procedure, and at least one safety consideration with rationale for the C. elegans heavy-metal investigation.
  4. 4
    Submit it here
    1. 1CMSD website. Go to clevelandmetroschools.org and click the Clever button.
    2. 2Clever. Clever opens. Sign in if it asks.
    3. 3Microsoft (district) login. Use your district Microsoft account (the one for school).
    4. 4Schoology. Open Schoology, then your class, then Assignments, and find the file named below.
    The file to submit is named: Human Anatomy & Physiology (Human Body Systems) › Unit 2.3 Challenge Accepted: Open-ended C. elegans/heavy metal investigation or validated simulation; data and conclusions. › Pre-lab
    Open Schoology
Were you absent? Jump to the make-up plan
Where this fits
Tested on (Ohio WebXam)
Human Anatomy and Physiology · 072040
PLTW lesson
HBS · Hypothesis and protocol
WebXam domain
Human Body Form, Function, and Pathophysiology
Evidence to produce
Pre-lab
Lab / skill
CDC: Lead poisoning prevention
Quick glossary
CER:
Claim, Evidence, Reasoning — make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure — the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities — you open it through Schoology.
Learn first

Minute-by-minute · 80-minute block

💡 Big idea: A hypothesis is a specific, testable prediction that drives the design of every step in an experiment.

  1. 0-10Notes: if-then hypothesis structure and common mistakes
  2. 10-25Write your if-then hypothesis for the heavy-metal C. elegans investigation
  3. 25-42PLTW online protocol-planning activity
  4. 42-58Draft complete materials list and step-by-step procedure
  5. 58-70Add one safety consideration with a rationale for each precaution
  6. 70-80Partner review of hypothesis and protocol; submit pre-lab
Mr. Mendoza's 5-minute intro
  • Tomorrow you run your C. elegans heavy-metal investigation, so today is about being ready.
  • A hypothesis written now will focus your data collection and analysis.
  • Your protocol is your recipe: if it is vague, your results will be uninterpretable.
  • You will also note the safety steps you must follow when working with heavy-metal solutions.
Do this, step by step
  1. 1Take notes on hypothesis structure and prediction.
  2. 2Write an if-then hypothesis for your investigation.
  3. 3Complete the PLTW online protocol-planning activity.
  4. 4List the materials and steps for your procedure.
  5. 5Note one safety consideration for heavy-metal handling.
You'll be able to
  • Hypothesis is testable and written in if-then form.
  • PLTW online task is submitted with a complete protocol.
Know by the end
  • An if-then hypothesis names the independent variable, predicts the direction of change, and identifies the dependent variable.
  • A protocol lists materials, step-by-step procedure, and safety precautions in enough detail to be replicated.
  • Heavy-metal exposures require careful handling protocols to protect the experimenter and prevent contamination.
📺 Tutor me: HHMI BioInteractive: Classroom resources
Do the work

Your PLTW work today

Open this PLTW section today

Unit 2.3 Challenge Accepted: Open-ended C. elegans/heavy metal investigation or validated simulation; data and conclusions. · Hypothesis and protocol

Day 2 of this lesson. Open this exact section in myPLTW (reached through Schoology), then do the work below.

Do this: Complete the protocol-planning online activity in Lesson 2.3 Challenge Accepted on myPLTW; finish all hypothesis and procedure screens during the 25-42 minute window.

Complete

Mark the protocol activity complete in myPLTW after submitting your pre-lab document.

How far to get

Monday's task is done; today the protocol task should show complete in your progress bar.

Upload as evidence

Screenshot or note of completion status for your tracker.

All PLTW activities are completed inside the PLTW course environment — this page only gives direction. Submit producibles on Schoology.

The plan

Today's PLTW tracker

Check things off as you work, then submit. This tells Mr. Mendoza how you're doing so he can help the class. It does not replace turning in your producible on Schoology.

Use the code Mr. Mendoza gave you, not your name. Saved on this device.

Unit 2.3 Challenge Accepted: Open-ended C. elegans/heavy metal investigation or validated simulation; data and conclusions.Day 2 of this projectSee the full week plan
Today's PLTW target

Unit 2.3 Challenge Accepted: Open-ended C. elegans/heavy metal investigation or validated simulation; data and conclusions. · Hypothesis and protocol

Complete the protocol-planning online activity in Lesson 2.3 Challenge Accepted on myPLTW; finish all hypothesis and procedure screens during the 25-42 minute window.

Monday's task is done; today the protocol task should show complete in your progress bar.

This is how Mr. Mendoza sees the class keeping pace with PLTW. Be honest, it only helps if it is accurate.

1 · What you do today

🎯 Students will write a hypothesis and protocol for a C. elegans heavy-metal investigation using teacher notes and the PLTW online task.

  • Take notes on hypothesis structure and prediction.
  • Write an if-then hypothesis for your investigation.
  • Complete the PLTW online protocol-planning activity.
  • List the materials and steps for your procedure.
  • Note one safety consideration for heavy-metal handling.
2 · Turn in today

Pre-lab: Written if-then hypothesis, complete materials list, step-by-step procedure, and at least one safety consideration with rationale for the C. elegans heavy-metal investigation.

Submit on Schoology

Upload by 11:29 PM for full credit.

3 · Who's doing what (team)
TaskWho
Take notes on hypothesis structure and prediction._______
Write an if-then hypothesis for your investigation._______
Complete the PLTW online protocol-planning activity._______
List the materials and steps for your procedure._______
Note one safety consideration for heavy-metal handling._______

Working solo? Put your own name in "Who" for every row.

4 · Words I can use correctly
5 · I'm successful today when I can…
  • Hypothesis is testable and written in if-then form.
  • PLTW online task is submitted with a complete protocol.
6 · Reflection & next steps
Where are you today?0/7 checked
Pick your period and code first.
Explore

Resources & readings

Vetted readings and references for this unit. Use them to prepare, to catch up if you were absent, or to go deeper on today's target.

Lab day

Lab & supplies

Bring / set up
C. elegans plates or validated heavy-metal simulationHeavy-metal solution or simulated treatment cardsStereo microscope or simulation deviceData table and graph paper or graphing appGloves and gogglesLab notebook
CDC: Lead poisoning prevention
Words

This unit's vocabulary

heavy metaltoxicology/tok-sih-KOL-uh-jee/hypothesis/hy-POTH-uh-sis/data tablegraphlimitationconclusion

Tap the speaker to hear a term. Weekly vocabulary task: add two of these terms to your notebook glossary with a definition and an example in your own words.

Check yourself

WebXam practice

Tap an answer to check it · nothing is recorded or graded
Heavy metals such as lead and mercury are dangerous to the body because they:
A well-written scientific hypothesis is best described as:
When organizing numeric results, a data table is most useful for:
Identifying the limitations of an experiment is important because it:
Check yourself

Cumulative WebXam review

A quick mixed-review pulling questions from earlier units plus today, so the WebXam material stays fresh.

Tap an answer to check it · nothing is recorded or graded
[Review: Reflexes: reaction time, signaling, and a patient diagnosis challenge] Why might a depressant drug increase a person's reaction time in a reflex test?
[Review: Everything Endocrine: hormones, feedback loops, and the blood-sugar model] Which gland releases glucagon when blood sugar falls too low?
[Review: Research Model: model organisms, C. elegans, and reading the literature] Increasing the sample size in a study generally:
Heavy metals such as lead and mercury are dangerous to the body because they:
Explore

Where this leads — careers

Safety net

What to do if you were absent

If YOU are absent

Today is individual PLTW work, so do exactly what we did in class, from home: complete the same PLTW target above, then submit your Pre-lab.

Open Schoology (CMSD) and keep going

How to get there: open the CMSD website, click Clever, sign in with your Microsoft (district) account, then open Schoology from Clever.

If MR. MENDOZA is absent

Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:

CDC: Lead poisoning prevention
Explore

Optional extra credit (async)

You've passed Unit 2, so the optional extra-credit track is open. Complete reserved-unit work from home (virtual labs included) for extra credit, all submitted on Schoology.

Open the extra-credit track
How this is graded
For: Pre-lab — Written if-then hypothesis, complete materials list, step-by-step procedure, and at least one safety consideration with rationale for the C. elegans heavy-metal investigation.
  • Complete
    Every required part of the artifact is present, nothing left blank.
  • Accurate
    The science and the data are correct and match the evidence.
  • Scientific reasoning
    You explain your claim with evidence and reasoning (CER), not just an answer.
  • Professional communication
    Clear, organized, labeled, and written the way a clinician or scientist would.
  • Submitted
    Turned in the right way (Schoology for routine work) and confirmed.
Submission Zone

Drop your Mon, Apr 12, 2027 · Hypothesis and protocol here. Use a clear file name (your initials + project). Routine work still goes to Schoology (via the CMSD portal).

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