Run the investigation
Students will conduct the C. elegans heavy-metal investigation and collect data on worm response.
Completed data table with results for all treatment concentrations and the control, consistent units, and notes on any unexpected observations.
- 1Do thisStudents will conduct the C. elegans heavy-metal investigation and collect data on worm response.
- 2Use this resource
- 3Submit thisData table: Completed data table with results for all treatment concentrations and the control, consistent units, and notes on any unexpected observations.
- 4Submit it here
- 1CMSD website. Go to clevelandmetroschools.org and click the Clever button.
- 2Clever. Clever opens. Sign in if it asks.
- 3Microsoft (district) login. Use your district Microsoft account (the one for school).
- 4Schoology. Open Schoology, then your class, then Assignments, and find the file named below.
The file to submit is named: Human Anatomy & Physiology (Human Body Systems) › Unit 2.3 Challenge Accepted: Open-ended C. elegans/heavy metal investigation or validated simulation; data and conclusions. › Data tableOpen Schoology
- CER:
- Claim, Evidence, Reasoning — make a claim, back it with evidence, explain your reasoning.
- SOP:
- Standard Operating Procedure — the exact steps to follow (especially in a lab).
- Tracker:
- Your PLTW progress log where you record completed evidence.
- myPLTW:
- The PLTW course site where you do the online activities — you open it through Schoology.
Minute-by-minute · 80-minute block
💡 Big idea: Running a controlled investigation generates the raw data that will be used to test a hypothesis and draw evidence-based conclusions.
- 0-10Safety review: handling heavy-metal solutions, disposal, PPE
- 10-20Set up exposure conditions and control; verify labels and concentrations
- 20-50Apply treatments; observe and record worm movement or survival at regular intervals
- 50-62Tabulate all results: condition, concentration, response metric, units
- 62-72Record any unexpected observations with description and time stamp
- 72-80Cleanup per safety protocol; submit completed data table
- • Your hypothesis is on paper; today you find out if the data supports it.
- • Following your protocol precisely is the difference between reliable data and noise.
- • Record everything, including observations you did not predict.
- • You will leave today with a complete data table ready for tomorrow's analysis.
- 1Set up the exposure conditions and your control.
- 2Apply the heavy-metal treatments at planned concentrations.
- 3Observe and record worm movement or survival over time.
- 4Tabulate results for each condition.
- 5Note any unexpected observations during the run.
- • Data is recorded for all treatment and control conditions.
- • Observations are logged with consistent units.
- • Every condition in an experiment, including the control, must be documented with the same level of detail.
- • Unexpected observations are scientifically valuable and must be recorded, not ignored.
- • Dose-response relationships are central to toxicology and connect to Anatomy/Physiology/Pathophysiology WebXam content.
Your PLTW work today
Unit 2.3 Challenge Accepted: Open-ended C. elegans/heavy metal investigation or validated simulation; data and conclusions. · Run the investigation
Day 3 of this lesson. Open this exact section in myPLTW (reached through Schoology), then do the work below.
Do this: Complete any lab-day check-in or data-entry prompt in Lesson 2.3 Challenge Accepted on myPLTW that accompanies today's C. elegans heavy-metal investigation; log it after tabulating your results.
Mark the lab-day task complete in myPLTW after submitting your completed data table.
Protocol task is done; today the lab task should show complete alongside your submitted data table.
Note or screenshot of completion status for your tracker.
All PLTW activities are completed inside the PLTW course environment — this page only gives direction. Submit producibles on Schoology.
Today's PLTW tracker
Check things off as you work, then submit. This tells Mr. Mendoza how you're doing so he can help the class. It does not replace turning in your producible on Schoology.
Use the code Mr. Mendoza gave you, not your name. Saved on this device.
Unit 2.3 Challenge Accepted: Open-ended C. elegans/heavy metal investigation or validated simulation; data and conclusions. · Run the investigation
Complete any lab-day check-in or data-entry prompt in Lesson 2.3 Challenge Accepted on myPLTW that accompanies today's C. elegans heavy-metal investigation; log it after tabulating your results.
Protocol task is done; today the lab task should show complete alongside your submitted data table.
This is how Mr. Mendoza sees the class keeping pace with PLTW. Be honest, it only helps if it is accurate.
🎯 Students will conduct the C. elegans heavy-metal investigation and collect data on worm response.
- Set up the exposure conditions and your control.
- Apply the heavy-metal treatments at planned concentrations.
- Observe and record worm movement or survival over time.
- Tabulate results for each condition.
- Note any unexpected observations during the run.
Data table: Completed data table with results for all treatment concentrations and the control, consistent units, and notes on any unexpected observations.
Submit on SchoologyUpload by 11:29 PM for full credit.
| Task | Who |
|---|---|
| Set up the exposure conditions and your control. | _______ |
| Apply the heavy-metal treatments at planned concentrations. | _______ |
| Observe and record worm movement or survival over time. | _______ |
| Tabulate results for each condition. | _______ |
| Note any unexpected observations during the run. | _______ |
Working solo? Put your own name in "Who" for every row.
- Data is recorded for all treatment and control conditions.
- Observations are logged with consistent units.
Resources & readings
Vetted readings and references for this unit. Use them to prepare, to catch up if you were absent, or to go deeper on today's target.
Lab & supplies
- • Wear nitrile gloves and safety goggles at all times when handling heavy-metal solutions.
- • Never pipette by mouth; use mechanical pipette aids only.
- • Dispose of all heavy-metal waste in the designated container, not the sink.
- • Wash hands thoroughly after removing gloves and before leaving the lab.
- • Report any spills immediately to the teacher; do not attempt to clean chemical spills independently.
WebXam practice
Cumulative WebXam review
A quick mixed-review pulling questions from earlier units plus today, so the WebXam material stays fresh.
Where this leads — careers
What today's skills lead to. These are real health-science careers this course builds toward. Tap one to see, on the US Department of Labor's O*NET site, what the job actually involves, what it pays, and how fast it is growing.
What to do if you were absent
Run your heavy-metal exposure on C. elegans, recording response data for every concentration and the control.
HHMI BioInteractiveThen submit your Data table on Schoology.
Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:
CDC: Lead poisoning preventionOptional extra credit (async)
You've passed Unit 2, so the optional extra-credit track is open. Complete reserved-unit work from home (virtual labs included) for extra credit, all submitted on Schoology.
Open the extra-credit track- CompleteEvery required part of the artifact is present, nothing left blank.
- AccurateThe science and the data are correct and match the evidence.
- Scientific reasoningYou explain your claim with evidence and reasoning (CER), not just an answer.
- Professional communicationClear, organized, labeled, and written the way a clinician or scientist would.
- SubmittedTurned in the right way (Schoology for routine work) and confirmed.
Drop your Tue, Apr 13, 2027 · Run the investigation here. Use a clear file name (your initials + project). Routine work still goes to Schoology (via the CMSD portal).
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