Semester 2 (Spring) · Week 12 of 15 teaching weeksApr 13–16

Unit 2.3 Challenge Accepted: Open-ended C. elegans/heavy metal investigation or validated simulation; data and conclusions.

Your PLTW coursework: Human Body SystemsUnit 2: Research Ready ▸ Lesson 2.3 Challenge Accepted ▸ "Problem 2.3.1 Challenge Accepted (C. elegans research)"

What to do if absent
Color keyLearn firstGet orientedDo the workLab daySafety netCheck yourself
Portal terms
CER:
Claim, Evidence, Reasoning: make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure, the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities. Find it in Clever with your Microsoft sign-in, right next to Schoology.
Learn first

Week overview - Challenge Accepted: a model-organism investigation into heavy metals

Apr 13–16

Carry out an open-ended C. elegans or simulated heavy-metal investigation, record clean data, and write a conclusion that names its limitations.

Week arc
  1. 1Review your hypothesis and the rules for working with a or simulation.
  2. 2Set up your treatment and control conditions and define what data you will collect.
  3. 3Run the investigation and record results in a clear, labeled .
  4. 4Build a graph that lets a reader see the pattern in your data at a glance.
  5. 5Write a conclusion that states whether your data support your hypothesis.
  6. 6Name at least two limitations and explain how they could affect your conclusion.
By week end
  • You will be able to organize results in a labeled and graph.
  • You will be able to write a conclusion that is supported by your data.
  • You will be able to name limitations that affect how far your conclusion can go.
The plan

Daily lessons this week

Open any day for its full lesson, the work due that day, and guided notes.

TuesdayTue, Apr 13
Heavy-metal exposure debate

Written position on heavy-metal exposure responsibility, citing one factual reason and naming one genuine tradeoff in regulation.

ThursdayThu, Apr 15
Hypothesis and protocol

Written if-then hypothesis, complete materials list, step-by-step procedure, and at least one consideration with rationale for the C. elegans heavy-metal investigation.

FridayFri, Apr 16
Run the investigation

Completed with results for all treatment concentrations and the control, consistent units, and notes on any unexpected observations.

Thursday
Data analysis and limitations

Written CER with a dose-response claim, two specific data-point evidence entries, reasoning linking dose to worm response, and at least two limitations of the investigation.

Friday
Submit tracker and evidence

Completed weekly progress tracker showing submission status for the pre-lab, , graph, and CER, plus a written reflection proposing one concrete improvement to the investigation.

Get oriented

Quick intro to the week

  • Hook: toxicologists use tiny organisms to find out what doses are dangerous, and today you run that kind of investigation yourself.
  • Today's goal: produce clean data, a clear graph, and an honest conclusion that admits its limits.
  • This week's Monday bioethics debate: how much risk is acceptable when testing chemical ?
  • Reminder: your graded research report with limitations lives in the PLTW course shell, not on loose paper.
Do the work

Your PLTW coursework this week

Do this: Advance the PLTW Challenge Accepted benchmark by completing the online evidence for the open-ended investigation in the course shell.

Know when done
  • Toxicology studies how the dose of a substance like a affects living things.
  • A and graph make patterns in evidence visible to a reader.
  • Every investigation has limitations that bound its conclusions.
Be able to do
  • Record and graph investigation data accurately.
  • Write a conclusion that connects evidence to the hypothesis and states limitations.

📋 PLTW evidence due: research report with , graph, conclusion, and named limitations, submitted on the class site.

All PLTW activities are completed inside the PLTW course environment: this page only gives direction.

The plan

This week's PLTW tracker

Your week at a glance. Check off each deliverable as you finish it, then submit so Mr. Mendoza can see how the class is pacing.

Use the code Mr. Mendoza gave you, not your name. Saved on this device.

DayDateFocusKey deliverable
TuesdayTue, Apr 13Heavy-metal exposure debate Written position on heavy-metal exposure responsibility, citing one factual reason and naming one genuine tradeoff in regulation.
ThursdayThu, Apr 15Hypothesis and protocol Written if-then hypothesis, complete materials list, step-by-step procedure, and at least one safety consideration with rationale for the C. elegans heavy-metal investigation.
FridayFri, Apr 16Run the investigation Completed data table with results for all treatment concentrations and the control, consistent units, and notes on any unexpected observations.
Thursday-Data analysis and limitationsWritten CER with a dose-response claim, two specific data-point evidence entries, reasoning linking dose to worm response, and at least two limitations of the investigation.
Friday-Submit tracker and evidenceCompleted weekly progress tracker showing submission status for the pre-lab, data table, graph, and CER, plus a written reflection proposing one concrete improvement to the investigation.
Check off as you finish
  • First class day: bioethical debate (Monday is a closure)
  • T: teacher background notes + PLTW launch task
  • W: lab / data or model work
  • Th: analysis / CER or design revision
  • F: submit tracker + weekly evidence

Due by week's end: Research report with limitations.

Where are you this week?0/5 checked
Pick your period and code first.
The week, drawn

5 panels from the illustrated semester.

Comic panel 62: Data analysis and limitations. Dose response claim, two specific data points as evidence, and a limitations section that had to name the timing problem honestly.
62Data analysis and limitations
Comic panel 53: Submit tracker and evidence. Sunday packet. The tracker caught a lab report I thought I had uploaded and had not.
53Submit tracker and evidence

Fiction. There is no such student. The lessons, labs and dates are the real planned course; the student, the classmates and the conversations are invented.

Lab day

Lab day: what to bring & watch

Equipment you'll need
C. elegans plates or validated heavy-metal simulationHeavy-metal solution or simulated treatment cardsStereo microscope or simulation deviceData table and graph paper or graphing appGloves and gogglesLab notebook
CDC: Lead poisoning prevention

This explainer accompanies the PLTW lab protocol: watch it before lab.

Safety net

What to do when absent

If YOU are absent

Most days, this class is your PLTW coursework: and PLTW is online and individual. So being out usually just means doing exactly what we did in class, from home.

Open Clever, then myPLTW

How to get there: open Clever and sign in with your Microsoft (district) account. Both myPLTW and Schoology are in Clever. Do the activity in myPLTW. Turn the work in on this site or hand it to Mr. Mendoza, because that is the step that counts as submitted. Schoology only shows your report-card grade later.

Was today a lab or a group activity?

You can't do those from home: do this instead: Teacher-posted data/model packet, same objective. Supplemental: Khan: data displays/statistics.

If MR. MENDOZA is absent

Class still runs. A substitute will post today's plan: complete the online activity above; it's built to be self-guided. Need the concept taught without a teacher? Use this authoritative explainer:

CDC: Lead poisoning prevention
Words

Vocabulary

heavy metaltoxicologyhypothesisdata tablegraphlimitationconclusion
Explore

Resources & readings

Aligned to

Standards this week

072040 · 2.2 Evaluate Body Systems
072040 · 5.3 Microbiology
NGSS science & engineering practices
Check yourself

WebXam practice

Tap an answer to check it · nothing is recorded or graded
Heavy metals such as lead and mercury are dangerous to the body because they:
A well-written scientific hypothesis is best described as:
When organizing numeric results, a data table is most useful for:
Identifying the limitations of an experiment is important because it: