The comic · Genetics of Disease (GenD)

Week 4 of 22

SEPTEMBER 10 TO 14

Fiction. No real student, family or grade appears.

Drawing, panel 16: DNA sequencing basics.

How sequencing actually produces a readable order of bases, and why that string is enough to identify an organism.

Panel 16DNA sequencing basics
Drawing, panel 17: BLAST computer lab.

The whole class in the computer lab running BLAST, which compares an unknown sequence against a global database and ranks what it matches.

ME

A confident top hit that covers a tenth of your sequence means nothing. I would have been fooled yesterday.

Panel 17BLAST computer lab · 2026-09-10
Drawing, panel 18: E-value and query coverage.

The part that separates a real match from a coincidence. A low E-value means the match is unlikely to be chance, and query coverage tells you how much of your sequence actually lined up.

Panel 18E-value and query coverage · 2026-09-11
Drawing, panel 19: Pathogen-ID report submission.

Full report: sequence, BLAST result, E-value, coverage, and a statement of what the identification does not prove.

Panel 19Pathogen-ID report submission · 2026-09-14
Week 3Week 5