Biotechnology for Health (BFH)

The comic

What We Hope The Year Will Be Like

Biomedical Innovations · 83 panels · the same year, drawn

Or read the whole year in one scroll

83 panels · about 44 screens · it starts below

Week 1

JANUARY 19 TO 26

Read this week
Drawing, panel 1: Welcome and expectations.

First day. No syllabus read out loud. He put a question on the board, let us list what we would need to know to answer it, then told us the list was the course. Eighteen weeks of open problems with no answer key, which he said out loud on day one.

Panel 1Welcome and expectations · 2027-01-19
Drawing, panel 2: How to use the class website.

Website day. Where the lesson lives, where the glossary is, and which folder every kind of work goes to. The practice section is open from day two, which I did not expect.

Panel 2How to use the class website · 2027-01-20
Drawing, panel 3: Cornell notes and the 6 Rs.

Record, Reduce, Review, Reflect, Recite, Revise. He made us Reduce notes we had just taken, and it showed how much I had written down and could not say back.

Panel 3Cornell notes and the 6 Rs · 2027-01-21
Drawing, panel 4: Lab safety and how to submit.

Safety, and not as a formality. Protective equipment, then finding the hazard and first aid sections on a real chemical before anyone touched anything.

Panel 4Lab safety and how to submit · 2027-01-25
Drawing, panel 5: WebXam pretest and goal setting.

The WebXam pretest in week one, cold. Mine was low. Everyone's was. Then we each wrote one habit down, and mine is fifteen minutes a night.

Panel 5WebXam pretest and goal setting · 2027-01-26

Week 2

JANUARY 27 TO FEBRUARY 2

Read this week
Drawing, panel 6: BI launch and syllabus.

He opened by saying this course has no answer key, which got a laugh and turned out to be literal. In the other three classes the lab has a right result.

MR. MENDOZA

This course has no answer key. You define the problem and the only test is whether the thing works.

Panel 6BI launch and syllabus · 2027-01-27
Drawing, panel 7: Lab safety and SDS.

Safety again, because we will be in the lab and also using tools. PPE, the Safety Data Sheet, hazard and first aid sections.

Panel 7Lab safety and SDS · 2027-01-29
Drawing, panel 8: Design notebook setup.

A design notebook is different from a lab notebook. It keeps the dead ends.

Panel 8Design notebook setup · 2027-02-01
Drawing, panel 9: First BI evidence entry.

First real entry. We had to observe something in the world and write down a problem we noticed, without proposing a solution yet.

ME

I wrote three problems and all three were solutions wearing a problem costume.

Panel 9First BI evidence entry · 2027-02-02
Drawing, panel 10: Submit setup check.

Notebook, safety, first entry.

Panel 10Submit setup check
Drawing, panel 11: Why I am here.

I want to build things that go in hospitals. Not be the doctor, be the person who designed the thing the doctor is using and made it not terrible.

Panel 11Why I am here

Week 3

FEBRUARY 3 TO 9

Read this week
Drawing, panel 12: Speed-vs-equity debate.

Should an emergency room be designed for average speed or for the sickest patient? Optimizing throughput means the median person waits less and the rare complicated one waits much longer.

Panel 12Speed-vs-equity debate · 2027-02-03
Drawing, panel 13: Stakeholder map.

Everyone affected by the ER, not just patients. Nurses, triage, registration, cleaning staff, families in the waiting room, the ambulance crew who cannot leave until they hand off.

TEAMMATE

Nobody thought about the ambulance crew. They cannot leave until they hand off.

Panel 13Stakeholder map · 2027-02-04
Drawing, panel 14: Patient flow workflow.

Mapping the actual path a patient takes, step by step, with the waits marked. The waits are where the design problem lives.

Panel 14Patient flow workflow · 2027-02-08
Drawing, panel 15: Team contract.

We wrote and signed an actual team contract: who does what, how we decide when we disagree, and what happens if somebody does not deliver.

Panel 15Team contract
Drawing, panel 16: ER inefficiency brief.

A brief naming one specific inefficiency with evidence from our flow map. Not the ER is slow. This step, this wait, this many minutes.

Panel 16ER inefficiency brief · 2027-02-09

Week 4

FEBRUARY 10 TO 16

Read this week
Drawing, panel 17: Research kickoff.

Turning our inefficiency into a researchable question. Ours started as why is the ER slow and ended as how does information handoff at triage affect time to first assessment, which is a question you can actually go.

Panel 17Research kickoff
Drawing, panel 18: Credible source check.

Criteria for a credible source, applied to five things we found. Two of ours failed, including one that looked completely professional and turned out to be a company selling the solution it recommended.

ME

It looked completely professional. It was a company selling the solution it recommended.

Panel 18Credible source check
Drawing, panel 19: Annotation and citation.

Annotating properly: what the source claims, what evidence it gives, and what it does not cover. Then citing so somebody else can find it.

Panel 19Annotation and citation · 2027-02-10
Drawing, panel 20: Submit research notes.

Annotated sources with citations and a summary of what we still do not know.

Panel 20Submit research notes · 2027-02-16

Week 5

FEBRUARY 17 TO 22

Read this week
Drawing, panel 21: ER-ethics debate.

Whether a design that helps most patients but disadvantages a specific group is acceptable if the overall numbers improve.

Panel 21ER-ethics debate · 2027-02-17
Drawing, panel 22: Design brief.

The brief: problem, users, criteria, constraints. Constraints are the ones people skip and they are what make a design real. Budget, space, staffing, and the fact that you cannot rebuild a hospital.

Panel 22Design brief
Drawing, panel 23: CAD floor plan modeling.

First time in CAD. Drawing a floor plan to scale, which immediately kills ideas that worked fine as sketches. Our redesigned triage area did not physically fit.

ME

It does not fit. Scale is a brutal critic and you cannot argue with a wall.

Panel 23CAD floor plan modeling · 2027-02-18
Drawing, panel 24: Process flowchart.

The new patient flow through our redesign, next to the old one, so the improvement is visible rather than claimed.

Panel 24Process flowchart · 2027-02-19
Drawing, panel 25: Prototype revision log.

Documenting every change and why. The log is the deliverable, not just the final plan, because the reasoning is what gets assessed.

Panel 25Prototype revision log · 2027-02-22

Week 6

FEBRUARY 24 TO MARCH 2

Read this week
Drawing, panel 26: Innovation-safety debate.

How much testing before a new device reaches patients. Speed against safety, and the people harmed by delay are invisible in a way the people harmed by a bad device are not.

Panel 26Innovation-safety debate · 2027-02-24
Drawing, panel 27: Presentation prep.

Preparing to defend the design. He told us the audience is not there to be impressed, they are there to find the weak point, and our job is to have already found it.

Panel 27Presentation prep
Drawing, panel 28: ER presentation.

We presented. The question that got us was whether our redesign made the ambulance handoff worse, and it does, slightly. We had not measured it because it was not our focus.

AUDIENCE

Does your redesign make the ambulance handoff worse?

Panel 28ER presentation · 2027-02-25
Drawing, panel 29: Physiology variables.

New problem. Human physiology, and what you can actually measure on a person in a classroom: heart rate, reaction time, grip strength, breathing rate.

Panel 29Physiology variables · 2027-02-26
Drawing, panel 30: Research design ticket.

A testable question with variables defined. Mine was too broad twice before it was answerable.

Panel 30Research design ticket · 2027-03-02
Drawing, panel 31: HOSA meeting.

HOSA competitive events. I am looking at one on medical innovation, which is close enough to this class that the preparation counts twice.

Panel 31HOSA meeting

Week 7

MARCH 3 TO 8

Read this week
Drawing, panel 32: Data-ethics debate.

Measuring classmates and then analyzing the results. Consent, and what happens to the data after.

Panel 32Data-ethics debate · 2027-03-03
Drawing, panel 33: Experimental vs observational.

If you control the variable it is experimental. If you only watch, it is observational and you cannot claim cause.

Panel 33Experimental vs observational
Drawing, panel 34: Physiology sensor lab.

Sensors on people, multiple trials, units on everything. Our first trials were inconsistent because we were not standardizing rest between them.

Panel 34Physiology sensor lab · 2027-03-04
Drawing, panel 35: Mean, SD, t-test.

Statistics with a purpose. Mean and standard deviation, then a t-test to ask whether two groups actually differ or whether the difference is noise.

ME

It looked convincing in the bar chart and it did not survive the t-test.

Panel 35Mean, SD, t-test · 2027-03-05
Drawing, panel 36: Submit data table.

Raw data, statistics, and an honest statement that our result was not significant.

Panel 36Submit data table · 2027-03-08

Week 8

MARCH 10 TO 16

Read this week
Drawing, panel 37: Biometric-privacy debate.

Fingerprints and face data are different from a password because you cannot change them after a breach.

Panel 37Biometric-privacy debate · 2027-03-10
Drawing, panel 38: Bias, error, graph choice.

How the same honest data becomes a different claim depending on axis range, bar versus line, and what you leave out.

Panel 38Bias, error, graph choice · 2027-03-11
Drawing, panel 39: Statistics lab analysis.

Reanalyzing our week six data properly, with the axis honest and the non-significant result reported as non-significant.

MR. MENDOZA

Nobody lied. Same data, two pictures, opposite claims.

Panel 39Statistics lab analysis · 2027-03-12
Drawing, panel 40: CER mini-report.

Claim, evidence, reasoning, limitations. My claim had to be that we found no significant difference, which is a real finding and does not feel like one.

Panel 40CER mini-report · 2027-03-16

Week 9

MARCH 17 TO 19

Read this week
Drawing, panel 41: Innovation debate.

Whether incremental improvement or radical redesign does more good. Incremental helps sooner and reaches fewer people. Radical might help enormously or might never ship.

Panel 41Innovation debate · 2027-03-17
Drawing, panel 42: Problem definition.

Defining our own problem, properly, with evidence that it is real and affects specific people.

Panel 42Problem definition · 2027-03-18
Drawing, panel 43: Design criteria and constraints.

Criteria are what success looks like, constraints are what you cannot change. Mine include that it still has to be childproof, which is the entire difficulty.

ME

Easy for weak hands and hard for curious ones are nearly opposite requirements.

Panel 43Design criteria and constraints
Drawing, panel 44: Design sprint and tradeoffs.

Fast sketching, many ideas, then killing most. Every idea traded one requirement against another and the log has to say which trade I made and why.

Panel 44Design sprint and tradeoffs
Drawing, panel 45: Submit innovation proposal.

Problem, evidence, users, criteria, constraints, three concepts, one recommendation.

Panel 45Submit innovation proposal · 2027-03-19
Drawing, panel 46: Chess club.

Chess. I am losing less badly. Someone pointed out I commit to a plan early and will not abandon it even when the board changes.

CLASSMATE

You commit early and you will not abandon a plan even when the board changes.

Panel 46Chess club

Week 10

MARCH 22 TO APRIL 5

Read this week
Drawing, panel 47: Source ethics debate.

Using a company's own research to justify their product, and whether disclosure is enough to fix the conflict.

Panel 47Source ethics debate · 2027-03-22
Drawing, panel 48: Literature review.

Finding what already exists. Four products already address my problem and two are quite good, which was deflating for an hour and then useful.

Panel 48Literature review · 2027-03-24
Drawing, panel 49: Decision matrix.

Scoring concepts against weighted criteria. The weighting is the argument, because whichever criterion you weight heaviest decides the winner before you score anything.

Panel 49Decision matrix · 2027-03-25
Drawing, panel 50: Validation plan.

How would we know if it worked? Actual measurable criteria and who we would test with. Mine has to include people with limited grip strength, because testing on my own hands proves nothing.

ME

My matrix picked the concept I already liked. Then I fixed the weights.

Panel 50Validation plan · 2027-04-05
Drawing, panel 51: MP1 tracker audit.

Marking period audit with an honest confidence rating.

Panel 51MP1 tracker audit

Week 11

APRIL 7 TO 12

Read this week
Drawing, panel 52: Environmental justice debate.

Why exposure is not evenly distributed, and whether that is an accident of geography or the result of decisions.

Panel 52Environmental justice debate · 2027-04-07
Drawing, panel 53: Exposure pathway.

Source, pathway, receptor. You can break the chain at any of the three, and which one you choose is a policy decision disguised as a technical one.

Panel 53Exposure pathway
Drawing, panel 54: Environmental data lab.

Real environmental data, multiple sites, comparing against a standard. Some sites exceeded it.

Panel 54Environmental data lab · 2027-04-08
Drawing, panel 55: Mitigation notes.

What would actually reduce exposure, ranked by where in the pathway it acts and what it costs.

ME

Telling people to stay indoors breaks the chain at the receptor and leaves the source running.

Panel 55Mitigation notes · 2027-04-09
Drawing, panel 56: Exposure map submit.

Map, data, mitigation ranking.

Panel 56Exposure map submit · 2027-04-12

Week 12

APRIL 13 TO 16

Read this week
Drawing, panel 57: Graph draft.

Straight into building the graph that carries our environmental claim. Axis honest, units labeled, standard marked as a reference line.

Panel 57Graph draft · 2027-04-13
Drawing, panel 58: CER paragraph.

One paragraph, claim to evidence to reasoning, with the limitation that our sampling was opportunistic rather than random.

Panel 58CER paragraph · 2027-04-15
Drawing, panel 59: Claim graph submit.

Graph and paragraph.

Panel 59Claim graph submit · 2027-04-16
Drawing, panel 60: Cleveland Clinic onboarding.

Clinic onboarding cleared. Twelve weeks from when I started.

Panel 60Cleveland Clinic onboarding

Week 13

APRIL 19 TO 22

Read this week
Drawing, panel 61: Public health debate.

When a public health measure restricts individual choice for collective benefit, and who decides the threshold.

Panel 61Public health debate · 2027-04-19
Drawing, panel 62: Line list.

Building a line list: one row per case, columns for the variables that might matter. The structure is what makes the pattern findable.

Panel 62Line list · 2027-04-21
Drawing, panel 63: Intervention model.

Modeling what changes if you intervene at different points, and how much you would have to do to matter.

Panel 63Intervention model
Drawing, panel 64: Intervention plan.

A specific plan with a target, a mechanism, and a measure of success.

Panel 64Intervention plan · 2027-04-22

Week 14

APRIL 23 TO 29

Read this week
Drawing, panel 65: Risk communication debate.

How much uncertainty to include in a public health message. Too much and nobody acts, too little and you have overstated what you know.

Panel 65Risk communication debate · 2027-04-23
Drawing, panel 66: Message draft.

Writing for people who are not in this class. Short, accurate, actionable.

Panel 66Message draft · 2027-04-26
Drawing, panel 67: Privacy check.

Auditing our own product for what it collects and whether it needs to. The answer for two fields was no, and we had included them because they seemed useful.

Panel 67Privacy check · 2027-04-27
Drawing, panel 68: Wireframe build.

Sketching screens. Our personas were basically us until a teammate pointed out that neither of us is an older person on a slow connection, and half our features served nobody but ourselves.

TEAMMATE

Neither of us is an older person on a slow connection. Half these features serve nobody but us.

Panel 68Wireframe build
Drawing, panel 69: Product submit.

Message, wireframes, privacy audit, personas.

Panel 69Product submit · 2027-04-29

Week 15

APRIL 30 TO MAY 3

Read this week
Drawing, panel 70: Engineered organism debate.

Releasing an engineered organism, even a beneficial one, and the fact that you cannot recall it afterward.

Panel 70Engineered organism debate · 2027-04-30
Drawing, panel 71: Workflow notes and controls.

The molecular workflow and where controls sit in it. Positive, negative, and what each one rules out.

Panel 71Workflow notes and controls · 2027-05-03
Drawing, panel 72: Research experience.

The optional research extra credit. A university lab hosted a few of us and I spent most of the morning in the engineering side watching a 3D printer build a small device.

RESEARCHER

The best designers I work with spend more time with users than with CAD.

Panel 72Research experience

Week 16

MAY 5 TO 10

Read this week
Drawing, panel 73: Biotech safety debate.

Containment levels and who is responsible when something leaves a lab. The answer is usually a system rather than a person, which is comforting and also how nobody ends up accountable.

Panel 73Biotech safety debate · 2027-05-05
Drawing, panel 74: Transformation notes.

Getting bacteria to take up a plasmid, and why only a small fraction do. The selection step is what finds the ones that worked.

Panel 74Transformation notes
Drawing, panel 75: Transformation and gel wet lab.

The wet lab. Transformation, then a gel to confirm it. My plate had colonies where the control said there should be none, which means contamination somewhere in my technique.

ME

Four courses in and my aseptic technique is still the weakest thing I do.

Panel 75Transformation and gel wet lab · 2027-05-06
Drawing, panel 76: Gel map.

Mapping the bands against the ladder to work out fragment sizes. My gel was readable despite the plate problem, which is a small mercy.

Panel 76Gel map · 2027-05-07
Drawing, panel 77: Notebook submit.

Protocol, plate results, gel image, and the contamination written into the limitations rather than quietly omitted.

Panel 77Notebook submit · 2027-05-10

Week 17

MAY 11 TO 14

Read this week
Drawing, panel 78: Research ethics debate.

The last Monday. Research ethics, and we were asked to name one position we had changed across the whole year.

Panel 78Research ethics debate · 2027-05-11
Drawing, panel 79: Forensic evidence table.

Organizing evidence so somebody else could audit the chain of reasoning. Same discipline as the design log, applied to a different problem.

Panel 79Forensic evidence table · 2027-05-13
Drawing, panel 80: Project question.

Defining the final project question, which after seventeen weeks I can now do in one period instead of three.

Panel 80Project question · 2027-05-14
Drawing, panel 81: Portfolio audit.

Everything against the rubric. Mine was mostly complete and the gaps were labels and dates, not missing work, which is its own lesson about doing it properly at the time.

Panel 81Portfolio audit
Drawing, panel 82: Final portfolio submit.

Submitted. Seventeen weeks, four design problems, one portfolio.

Panel 82Final portfolio submit
Drawing, panel 83: The reason.

The optional research extra credit. A university lab hosted a few of us and I spent most of the morning in the engineering side watching a 3D printer build a small device.

Panel 83The reason

Fiction. No real student, family, grade, or conversation appears here. The lessons, labs and dates are the real planned course.