Rough draft.This research track is under review with Dr. Atit's lab. Content and sequence may still change.
Back to the session
Curriculum and WebXam connections
AlphaFold and UniProt: structure tells function
How this session lines up with the PLTW curriculum and the WebXam for each class it touches, including the vocabulary, concepts, and skills you share.
The classes below may be taught in different terms. This research track runs all year with HOSA, so a connection means the ideas line up, not that the class meets this week.
HBSHuman Body Systems Spring
PLTW alignment
HBS ties structure to function across the body.
WebXam
072040 Human Anatomy and Physiology
Domain: Human Body Form, Function, and Pathophysiology
How it connects
HBS's structure-to-function theme scales down to a single protein here.
Shared concepts
Structure determines functionProtein domain
Shared skills
Read a 3D structure
BIBiomedical Innovations Spring
PLTW alignment
BI research can use structure-prediction tools.
WebXam
072125 Biotechnology for Health and Disease
Domain: Bio-Molecular Technology
How it connects
An AlphaFold comparison is a feasible BI computational project.
Shared concepts
Protein structureVariant effect
Shared skills
Compare wild-type vs mutant structure