Karyotype case analysis
Fri, Oct 30, 2026 · Week 10 · Principles of Biomedical Technology (Principles of Biomedical Science)
Today's goal: Students individually arrange and interpret a karyotype to identify a chromosomal abnormality in a patient case.
What a finished product looks like
This is a model of the work you should turn in today. Use it to check your own: match the structure and the level of detail, do not copy it. Your data and wording should be your own.
Karyotype lab (Patient A):
- SOP followed: cut each chromosome image, sort by size (largest to smallest), align by centromere position and banding pattern, place into 22 numbered autosome pairs plus the sex pair.
- Variables: independent variable is the patient's chromosome images; dependent variable is the final pair count and arrangement.
- Result: 22 normal autosome pairs and XX, but chromosome 21 has three copies instead of two.
- Abnormality named: Trisomy 21 (Down syndrome).
- Procedural limitation: if two chromosomes have similar size and banding, I could mis-pair them, which would produce a false reading; poor image quality makes this worse.
Also due today: Turn in the mounted karyotype and the written abnormality statement to the collection tray before the period ends.
WebXam problem for today's skill
One exam-style question that uses exactly what you practiced today. Try it before you reveal the answer, then read why each choice is right or wrong.
Tap an answer to see the full explanation. Nothing is recorded or graded.