MI CFA: Unit 2: Screen Your Genes

A short unit check. Enter your Student ID and answer each item. This is practice, not a grade.

1. 1. On a pedigree, two unaffected parents have a child who is affected by a trait. The mother's brother is affected too. The trait is most likely:

   ADominantBRecessiveCA new mutationDEnvironmental

2. 2. In PCR, the primers determine:

   AWhich nucleotides get added to the new strandBHow many cycles the reaction runsCWhich enzyme copies the DNADWhere copying starts on the template DNA

3. 3. On an expression heat map, the color of each cell most directly shows a gene's:

   ADNA sequence in that sampleBNumber of copies in the genomeCShape as a finished proteinDRelative mRNA expression level

4. 4. A viral vector in gene therapy is used to:

   AInfect the patient with a new disease on purposeBCut the faulty gene out of the genomeCDeliver a working gene into a patient's cellsDRead the patient's whole genome

5. 5. Which order moves correctly from molecule to care?

   AConfirm the result, then look for the variantBDetect the variant, confirm it, then treatCTreat first, then test to confirm the choiceDReport the variant to the family, then confirm it

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