Tue, Mar 23, 2027Spring (Semester 2) · Week 10Day 33 of 5780-min blockTight fit

Endocrine glands and signaling

Essential question: How does one part of the body tell a distant part what to do without any nerve connecting them?Enduring understanding: The endocrine system coordinates organs that never touch by releasing hormones into the blood, and each only moves the cells built to receive it.

Do now

Students will map the major endocrine glands and the hormones they secrete using teacher notes and the PLTW online task.

DueTonight, 11:29 PM
Hand in
Annotated body diagram labeling at least four endocrine glands with their primary hormones, plus definitions of hormone, target cell, and receptor.
Where
Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

You get two school days for every day you were absent, so this deadline moves with you.

Where you are · this course
Unit 2.2 Everything Endocrine: Endocrine glands, hormones, feedback loops, blood sugar/insulin model. Endocrine glands and signaling ▸ Day 2
Day 33 of 57 this semester24 left before WebXam
🧬 Where you are · PLTW
Human Body SystemsUnit 2: Research Ready ▸ Lesson 2.2 Everything Endocrine"Activity 2.2.2 A-Mazing Worms (C. elegans)"
Activity names confirmed from PLTW's published HBS career-connections and Mr. Mendoza's licensed updated-HBS materials. Mr. Mendoza will confirm the exact numbering in myPLTW once the course shell opens.
Today's driving question

The thyroid sits in your neck but sets the metabolic pace of your whole body; how does a signal made in the neck reach and change a cell in your foot?

Today you'll be able to

Students will map the major endocrine glands and the hormones they secrete using teacher notes and the PLTW online task.

You've got it when
  • Body diagram labels at least four glands with correct hormones.
  • PLTW online task is submitted with all matches attempted.
Due today · Vocabulary task RequiredAnnotated body diagram labeling at least four endocrine glands with their primary hormones, plus definitions of , target cell, and .
Do-Now · start these with your notes closed
  1. Name one gland you already know and one thing it does.
  2. If a travels through the blood and reaches every cell, why does it only change some of them?
Do this · step by step
numbered so we can always find our place
  1. 1Take guided notes on the pituitary, thyroid, pancreas, and adrenal glands.
  2. 2Define , target cell, and in your own words.
  3. 3Complete the assigned PLTW online gland-and- matching activity.
  4. 4Annotate a body diagram with each gland and its primary .
  5. 5Write one question about a gland you still find confusing.
Interrupted or lost? Interrupted? Check that your notes cover the pituitary, thyroid, pancreas, and adrenal glands, that you have defined , target cell, and in your own words, then finish annotating each gland on the body diagram.
The story

What did this day actually feel like?

Endocrine glands and signaling

Four glands minimum on a body diagram with the hormone each releases. The endocrine system is the slow control system, chemical instead of electrical, and it reaches everywhere the blood does.

The comparison that landed: the nervous system is a phone call, the endocrine system is a letter to everybody at once.

Turned in: annotated gland diagram → recorded in Class Records

Fiction. There is no such student. The lessons, labs and dates are the real planned course; the student, the classmates and the conversations are invented.

The comic

The same day, drawn.

Drawing, panel 50: Endocrine glands and signaling.

Four glands minimum on a body diagram with the hormone each releases. The endocrine system is the slow control system, chemical instead of electrical, and it reaches everywhere the blood does.

Panel 50Endocrine glands and signaling · 2027-03-23
Read week 10, 5 panels

Fiction. There is no such student. The lessons, labs and dates are the real planned course; the student, the classmates and the conversations are invented.

🛠 Get unstuck · pick your level

Need a running start
Warm up the core idea with an analogy first: a hormone is like a key mailed to every house, but only the house with the matching lock opens. Then name the 'lock' in real biology (the receptor) before you map the glands.
On track
Map the pituitary, thyroid, pancreas, and adrenal glands to their main hormones, and explain in one sentence why a hormone reaches every cell but only changes cells with the matching receptor.
Stuck? Get unstuck
Absent? Use the guided notes and the PLTW matching activity, then label a body diagram with each gland and its primary hormone, and write your one lingering question so it gets answered.
Push me further
Pick one gland pair and explain a disorder in medical terms: contrast hypothyroidism and hyperthyroidism, and predict how each would change body temperature and energy, tying the prefix (hypo/hyper) to the symptom.

🔑 Today's words · 5

hormoneendocrine glandfeedback loopinsulinglucagon
+1 more in the word bank

Tap a word in the lesson for a plain meaning and one example. Recycled into next week's Do-Now.

Today's study notebook
The endocrine system: hormones and the negative-feedback loops that keep the body in balance.
Open the notebook
Watch first: today's 1-minute intro
Audio overviewVideo overviewMind mapStudy guideFlashcardsQuizData table
Where this fits
Tested on (Ohio WebXam)
Human Anatomy and Physiology · 072040 (likely, pending confirmation)
PLTW lesson
HBS · Lesson 2.2 Everything Endocrine
WebXam domain
Human Body Form, Function, and Pathophysiology
Evidence to produce
Vocabulary task
Lab / skill
MedlinePlus: Endocrine Diseases
Do the work · 80-minute blockfirst 5 min = hook

💡 Big idea: The endocrine system can coordinate distant organs because hormones travel through shared blood, so that any cell can be reached, while receptors decide which cells actually respond.

  1. 0-10Warm-up: name one gland and guess what it does
  2. 10-30Guided notes: pituitary, thyroid, pancreas, adrenal glands and their primary hormones
  3. 30-45Vocabulary pair-work: , target cell, in own words
  4. 45-60PLTW online gland-and- matching activity
  5. 60-72Annotate body diagram with glands and hormones
  6. 72-80Write one confusing question; share and submit diagram
Mr. Mendoza's 5-minute intro
  • Your endocrine system is sending chemical messages through your blood right now.
  • Today you will build a map of which glands send which messages and why.
  • Knowing gland- pairs is foundational for the WebXam /Physiology/Pathophysiology domain.
  • By the end you will have an annotated body diagram and a completed PLTW online activity.
Know by the end
  • Major endocrine glands include the pituitary, thyroid, pancreas, and adrenal glands, each secreting distinct hormones.
  • A only affects a target cell that carries the matching .
  • Medical terminology for endocrine pathophysiology links organ names to dysfunction (e.g., hypo/hyperthyroidism).
Open this PLTW section today

Unit 2.2 Everything Endocrine: Endocrine glands, hormones, feedback loops, blood sugar/insulin model. · Endocrine glands and signaling

Day 2 of this lesson. Open this exact section in myPLTW (find it in Clever, Microsoft sign-in), then do the work below.

Do this: Complete the gland-and- matching activity in Lesson 2.2 Everything Endocrine on myPLTW; work through all matching items during the 45-60 minute window.

Complete

Mark the matching activity complete in myPLTW after submitting your annotated body diagram.

How far to get

Introductory task is done; today the gland-and- task should show complete in your progress bar.

Upload as evidence

Screenshot or note of completion status for your weekly tracker.

The official PLTW activity stays inside myPLTW. If myPLTW will not open, use F1 and E1-E3 on this page to complete today's local evidence decision, then make up the official activity when access returns. Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

Today's PLTW tracker · fill in and submit

Check things off as you work, then submit. This tells Mr. Mendoza how you're doing so he can help the class. It does not replace turning in your producible through the submission route shown below.

Use the code Mr. Mendoza gave you, not your name. Saved on this device.

Unit 2.2 Everything Endocrine: Endocrine glands, hormones, feedback loops, blood sugar/insulin model.Day 2 of this projectSee the full week plan
Today's PLTW target

Unit 2.2 Everything Endocrine: Endocrine glands, hormones, feedback loops, blood sugar/insulin model. · Endocrine glands and signaling

Complete the gland-and- matching activity in Lesson 2.2 Everything Endocrine on myPLTW; work through all matching items during the 45-60 minute window.

Introductory task is done; today the gland-and- task should show complete in your progress bar.

This is how Mr. Mendoza sees the class keeping pace with PLTW. Be honest, it only helps if it is accurate.

1 · What you do today

🎯 Students will map the major endocrine glands and the hormones they secrete using teacher notes and the PLTW online task.

  • Take guided notes on the pituitary, thyroid, pancreas, and adrenal glands.
  • Define , target cell, and in your own words.
  • Complete the assigned PLTW online gland-and- matching activity.
  • Annotate a body diagram with each gland and its primary .
  • Write one question about a gland you still find confusing.
2 · What you turn in

Vocabulary task: Annotated body diagram labeling at least four endocrine glands with their primary hormones, plus definitions of , target cell, and .

Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not. Use the checklist just below and upload by 11:29 PM for full credit. Absent with an excused absence? You get two school days for every day you were absent, so this deadline moves with you.

3 · Who's doing what (team)
TaskWho
Take guided notes on the pituitary, thyroid, pancreas, and adrenal glands._______
Define , target cell, and in your own words._______
Complete the assigned PLTW online gland-and- matching activity._______
Annotate a body diagram with each gland and its primary ._______
Write one question about a gland you still find confusing._______

Working solo? Put your own name in "Who" for every row.

4 · Words I can use correctly
5 · I'm successful today when I can…
  • Body diagram labels at least four glands with correct hormones.
  • PLTW online task is submitted with all matches attempted.
6 · Reflection & next steps
Where are you today?0/7 checked
Pick your period and code first.
Your 4 steps today
  1. 1
    Do this
    Students will map the major endocrine glands and the hormones they secrete using teacher notes and the PLTW online task.
  2. 2
  3. 3
    Submit this
    Vocabulary task: Annotated body diagram labeling at least four endocrine glands with their primary hormones, plus definitions of hormone, target cell, and receptor.
  4. 4
    Submit it here
    1. 1Open the drop folder.
    2. 2Sign in with your district Microsoft account, not a personal one.
    3. 3Upload the file, named Lastname_Firstname__Assignment Title.
    4. 4Your own upload panel says Uploaded with a green check: that is your receipt.
    Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not. Human Anatomy & Physiology (Human Body Systems) › Unit 2.2 Everything Endocrine: Endocrine glands, hormones, feedback loops, blood sugar/insulin model. › Vocabulary task
    Open the drop folder
Were you absent? Jump to the make-up plan
Learn it · deck, reading, and vocabulary
Socratic teaching slide deck

The deck carries the prior idea forward, lets you inspect an analogy, maps the rule to biology, and ends with the same evidence decision and exit ticket used on this page.

Generated from this lesson's canonical data with a red-team citation check.

Carry forward

Medical decisions require weighing benefit, risk, and rights together, because a treatment that helps one goal can harm another, and no single stakeholder's wishes settle the question on their own.

Daily take-home

The endocrine system can coordinate distant organs because hormones travel through shared blood, so that any cell can be reached, while receptors decide which cells actually respond.

Inspect the analogy

A mechanic studies a tool whose shape allows one job but limits another.

  1. Which feature makes the tool work?
  2. What changes if that feature bends or breaks?
  3. Which observation shows function rather than appearance?
Rule

Structure creates possibilities and limits for function.

Where it breaks

Living tissues adapt and interact with other systems; a metal tool does not.

Map the analogy to biology
  • Tool shape maps to .
  • The job maps to physiological function.
  • Damage maps to a predicted functional change.
Read this first

Driving question: The thyroid sits in your neck but sets the metabolic pace of your whole body; how does a signal made in the neck reach and change a cell in your foot?

What you already know: Medical decisions require weighing benefit, risk, and rights together, because a treatment that helps one goal can harm another, and no single stakeholder's wishes settle the question on their own.

New idea: The endocrine system can coordinate distant organs because hormones travel through shared blood, so that any cell can be reached, while receptors decide which cells actually respond.

Visual or model: F1. F1. A lesson illustration or teaching diagram for Endocrine glands and signaling. Use it with E1-E3; it is a model or context image, not experimental or patient data. What to notice: Trace the labeled structure, movement, or system relationship that connects form to function.

  1. Observe or measure the relevant feature in Endocrine glands and signaling.
  2. Organize the observation with a stable evidence ID.
  3. Apply this rule: Structure creates possibilities and limits for function.
  4. Choose the option the evidence supports and state the limit of the conclusion.

Real biomedical example: The thyroid sits in your neck but sets the metabolic pace of your whole body; how does a signal made in the neck reach and change a cell in your foot?

What the evidence supports: E1-E3 and F1 support the daily take-home when the response meets the stated success criteria.

What it cannot prove: The package does not support claims beyond this lesson's or any real patient diagnosis.

Vocabulary:
  • : A chemical messenger made by glands and carried in the blood to distant organs, where it controls processes like growth, , and mood.
  • : An organ that releases hormones directly into the bloodstream to control distant body processes such as growth and .
  • : A control cycle in which the output of a process feeds back to adjust that same process, helping the body keep conditions stable.
  • : A made by the pancreas that lowers blood sugar by signaling cells to take in glucose from the blood.
  • : A made by the pancreas that raises blood sugar by signaling the liver to release stored glucose when levels drop.
  • : The body's ongoing process of keeping internal conditions like temperature, blood sugar, and pH steady despite changes in the outside environment.

Use it now: Choose one decision option. Cite E1 and E3, then explain how the rule connects the evidence to your choice.

Go further, optional: The source links below are optional enrichment. Every fact required for today's local evidence decision appears in this lesson package.

Evidence set and decision
E1 · Observation

Major endocrine glands include the pituitary, thyroid, pancreas, and adrenal glands, each secreting distinct hormones.

Limit: E1 supplies context or an observation; it does not by itself establish the explanation.

E2 · Mechanism

The endocrine system can coordinate distant organs because hormones travel through shared blood, so that any cell can be reached, while receptors decide which cells actually respond.

Limit: E2 is a teaching statement or comparison and must be checked against the task evidence.

E3 · Result

Body diagram labels at least four glands with correct hormones.

Limit: E3 supports only the result or product criterion named here; it cannot justify a broader clinical or causal claim.

PLTW-HAP-2027-03-23 · Simulated classroom evidence scenario

Your role: anatomy and physiology consultant

Decision: Your team must decide what the evidence from Endocrine glands and signaling supports before submitting the vocabulary application named on the lesson page.

  • Select the option best supported by E1-E3.
  • Select a reasonable alternative and name the evidence it would require.
  • Delay the claim because the evidence does not distinguish the options.

Response: State one choice, cite at least two evidence IDs, explain the rule that connects them, and add one limitation. Submit it as the vocabulary application.

Claim ceiling: The supplied lesson evidence can support an observation, pattern, classroom mechanism, or next-step decision about Endocrine glands and signaling. It cannot by itself prove causation, establish a real clinical diagnosis, or justify action outside this classroom task.

Composite case file · PLTW-HAP-2027-03-23

Reason for review: Your team must decide what the evidence from Endocrine glands and signaling supports before submitting the vocabulary application named on the lesson page.

Context: The endocrine system coordinates organs that never touch by releasing hormones into the blood, and each only moves the cells built to receive it.

Timeline:
  • T1: Take guided notes on the pituitary, thyroid, pancreas, and adrenal glands.
  • T2: Define , target cell, and in your own words.
  • T3: Complete the assigned PLTW online gland-and- matching activity.
  • T4: Annotate a body diagram with each gland and its primary .
  • T5: Write one question about a gland you still find confusing.
Evidence records:
  • E1: Major endocrine glands include the pituitary, thyroid, pancreas, and adrenal glands, each secreting distinct hormones.
  • E2: The endocrine system can coordinate distant organs because hormones travel through shared blood, so that any cell can be reached, while receptors decide which cells actually respond.
  • E3: Body diagram labels at least four glands with correct hormones.

Measurements: No patient measurement is supplied unless it appears explicitly in E1-E3 or F1. Do not invent a value.

Figure finding: Teaching diagram for Endocrine glands and signaling. Trace the labeled structure, movement, or system relationship that connects form to function. This is a teaching model, not patient or experimental data.

Uncertainty: This is a composite classroom scenario. Missing history, measurements, or confirmation tests remain unknown and limit the conclusion.

Watch the trap

Students often think Students think a released into the blood acts on whatever organ it reaches, so the gland must aim it at a target.. The trap: The blood carries a everywhere, but only cells with the matching respond, so targeting is done by the lock-and-key receptor on the cell, not by the gland aiming the signal. Miss this and endocrine signaling looks like guesswork instead of a specific match.

Worked example · a parallel case (guides, does not reveal)
Annotated gland diagram with vocabulary
Completes: An annotated body diagram labeling at least four endocrine glands with their primary hormones, plus student-worded definitions of hormone, target cell, and receptor.

Annotated glands and primary hormones:

  • Pituitary: growth hormone (also signals other glands).
  • Thyroid: thyroid hormone (sets metabolic rate).
  • Pancreas: insulin (and glucagon) for blood sugar.
  • Adrenal glands: adrenaline (the stress response).

Vocabulary in my own words:

  • Hormone: a chemical messenger that travels in the blood to change how a distant organ works.
  • Target cell: the specific cell a hormone is meant to affect.
  • Receptor: the matching dock on a target cell that the hormone binds to; without the right receptor, the hormone has no effect on that cell.

My lingering question: how does one gland (the pituitary) control several others at once?

GlandPrimary hormoneMain job
PituitaryGrowth hormoneGrowth, signals other glands
ThyroidThyroid hormoneSets metabolic rate
PancreasInsulinLowers blood glucose
AdrenalAdrenalineStress response
Table matching four endocrine glands to their primary hormone and main job.
Why this matters

This model shows the level of evidence and organization needed to complete: An annotated body diagram labeling at least four endocrine glands with their primary hormones, plus student-worded definitions of hormone, target cell, and receptor.

Build yours step by step
  1. Define the term in plain scientific language.
  2. Connect it to the current investigation.
  3. Use it accurately in a new example or contrast.
Change it for a new task

Keep the structure. Replace the question, facts, measurements, and evidence. Then recheck units, vocabulary, and whether the conclusion goes beyond the evidence.

Also due today: Submit your annotated diagram on the class site, or hand it to Mr. Mendoza in class.

See the full worked example
Portal terms
CER:
Claim, Evidence, Reasoning: make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure, the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities. Find it in Clever with your Microsoft sign-in, right next to Schoology.
This unit's vocabulary
/hoh-mee-oh-STAY-sis/

Tap the speaker to hear a term. Add two of these to your notebook glossary with a definition and an example in your own words.

Build your vocabulary · optional, for extra credit

Pick just 2 or 3 words from today and make them yours: write what each one means in your own words, name the context clue or evidence that helped, then give one example from what you actually did in Endocrine glands and signaling. Try your own words first; the glossary is there if you get stuck. This is voluntary and counts as extra credit, so keep it short.

hormone
endocrine gland
feedback loop
insulin
glucagon
homeostasis

Saved on this device. Show Mr. Mendoza or add these to your notebook glossary to claim the extra credit.

Unit notebook (fillable)

A fillable, Cornell-style notebook for Unit 2: Research Ready. Type your notes, cues, and summaries right in the PDF, or print it and write by hand. Each lesson page has a cue column, a notes column, and a summary box, plus dated lab-record pages you can turn in.

HBS Unit 2 notebook: Research Ready Fillable PDFCornell notes + lab recordsOpen
Resources & readings

Vetted readings and references for this unit. Use them to prepare, to catch up if you were absent, or to go deeper on today's target.

Check yourself · commit, then reveal

Claim ceiling for this check: The supplied lesson evidence can support an observation, pattern, classroom mechanism, or next-step decision about Endocrine glands and signaling. It cannot by itself prove causation, establish a real clinical diagnosis, or justify action outside this classroom task.

Quick self-check · commit, then reveal

Insulin travels in the blood past your muscle cells, liver cells, and skin cells. Why does it change how muscle and liver cells handle glucose but not, say, a hair follicle in the same way?

How sure are you?

Write an answer and pick a confidence to unlock the key.

Cumulative WebXam review · flash practice

Fast retrieval with instant answers, not the commit-then-reveal check above. Try each from memory first: write what you remember about the earlier units, then check yourself here.

Tap an answer to check it · nothing is recorded or graded
[Review: Relief Within Reach: empathy, patient data, and a rehabilitation plan] In a wellness context, the term range of motion refers to:
[Review: Getting Nervous: the brain, neurons, and how signals travel] Which brain region is primarily responsible for coordinating balance and fine motor movements?
[Review: Reflexes: reaction time, signaling, and a patient diagnosis challenge] Why might a depressant drug increase a person's reaction time in a reflex test?
Hormones are chemical messengers that travel through the body primarily via the:
Go further and get help
Where this leads: careers
What to do if you were absent
If YOU are absent

Today is individual work you can do from home: complete the same target above, then submit your Vocabulary task.

Open the drop folder

Turn this in at the drop folder with your district Microsoft sign-in, or hand it to Mr. Mendoza in class. Both count as submitted. Doing the activity in myPLTW does not.

If MR. MENDOZA is absent

Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:

MedlinePlus: Endocrine Diseases
Optional extra credit (async)

You've passed Unit 2, so the optional extra-credit track is open. Complete reserved-unit work from home, including virtual labs, for extra credit. Each item shows its correct submission route.

Open the extra-credit track
How this is graded
For: Vocabulary task: Annotated body diagram labeling at least four endocrine glands with their primary hormones, plus definitions of hormone, target cell, and receptor.
  • Complete
    Every required part of the artifact is present, nothing left blank.
  • Accurate
    The science and the data are correct and match the evidence.
  • Scientific reasoning
    You explain your claim with evidence and reasoning (CER), not just an answer.
  • Professional communication
    Clear, organized, labeled, and written the way a clinician or scientist would.
  • Submitted
    Turned in the right way, on the class site or handed to Mr. Mendoza in class, and confirmed. Not in Schoology: that is where the report-card grade appears later.