Principles of Biomedical Technology (Principles of Biomedical Science)
Unit 2: Unit 2.2 to 2.3 Genetic RiskPBS 2.2-2.3Biotechnology Research and Experiments

Read A Pedigree

Use a genetics model to read a pedigree with clear limits.

Builds on (2 levels back)inferred · high confidence
  • DNA/RNA base pairing: Sequence and codon tasks depend on reading bases in order.
  • Read a genetics model: Pedigrees, karyotypes, and charts are models that need a key.

Prerequisites are inferred: pending teacher review.

Re-learn the skill with worked practice and clear examples.

Use a genetics model to read a pedigree with clear limits.

Step 1: Learn the key
Read the genetic first, compare it to the key or chart, and separate risk from a confirmed .
Pedigree symbols showing shaded affected people and open unaffected people
Step 2: Use the model
Read the figure, table, control, range, or protocol before choosing an answer.
Step 3: Name the limit
Say what the evidence can support and what it cannot prove yet.
Practice

Use the genetics figure/table. Which interpretation is most careful?

Reviewed
Pedigree symbols showing shaded affected people and open unaffected people
  1. A.Leave out the people whose status is unknown
  2. B.Use the key/chart result and state only what it supports
  3. C.Guess the pattern from the shapes without reading the key
  4. D.Call every marked person in the chart a disease carrier
Show the worked solution ▾

Answer: B. Use the key/chart result and state only what it supports

  1. Step 1: Use the model: The figure/table provides the needed key.
  2. Step 2: Avoid overclaiming: Genetic evidence often shows risk or pattern, not certainty alone.

Why it's right: The careful answer uses the model and respects limits.

Why the others miss:
  • A: Unknown status is a limitation to state, not data to drop.
  • C: The key says what each shape means, so guessing skips the evidence.
  • D: A marked symbol can mean carrier, affected, or tested, depending on the key.

Aligned to Biotechnology Research and Experiments · reading level ~grade 9

In a standard pedigree, squares stand for males, circles for females, and a filled-in symbol means the person has the condition. What does a filled-in circle stand for?

Reviewed
  1. A.A female who does not have the condition
  2. B.A male who has the condition
  3. C.A female who has the condition
  4. D.A female carrier who shows no signs herself
Show the worked solution ▾

Answer: C. A female who has the condition

  1. Step 1: Read the shape: A circle stands for a female.
  2. Step 2: Read the fill: A filled-in symbol means the person has the condition.

Why it's right: The circle gives the sex and the fill gives the status, so a filled-in circle is a female who has the condition.

Why the others miss:
  • A: An unfilled circle would mean a female without the condition.
  • B: A male would be drawn as a square, not a circle.
  • D: Carrier status is not shown by a plain filled symbol; a filled symbol means the person is affected.

Aligned to Biotechnology Research and Experiments · reading level ~grade 9

Where you'd see this
  • In Unit 2.2 to 2.3 Genetic Risk, this skill turns class evidence into a result another person can check.
Video library
Watch: Read A Pedigree
Pedigrees
Amoeba Sisters · 8 min
Guided notes

Fill these in as you work through the lesson.

Big idea: Use a genetics model to read a pedigree with clear limits.
Key terms: write the meaning
  • Allele (version of a gene):  
  • Genotype (allele combination):  
  • Phenotype (observable trait):  
  • Carrier (has allele but may not show trait):  
The rule

Read the genetic   first, compare it to the key or chart, and separate risk from a confirmed  .

Check yourself
  1. What does the model key say? 
  2. What pattern or DNA change is shown? 
  3. Does this show risk, carrier status, or diagnosis? 
Work one example

Use the provided model to practice read a pedigree and write one cautious interpretation.