Rough draft.This research track is under review with Dr. Atit's lab. Content and sequence may still change.
Read it in pieces

When Could Mateo's Cleft Have Happened?

Take the reading one piece at a time. For each piece: read it once, underline the sentence that says what happens, then look up any word in the list. Tap a word to see its definition.

1

Piece 1 of 2

Read the timeline like a calendar of construction. In week 4 special migrating cells arrive and pile up into five small swellings (prominences) around the future mouth, and two pits that become the nostrils split the top swelling. During weeks 4 to 6 the upper lip closes as the swellings grow toward each other and join. The small front triangle of the roof of the mouth forms in weeks 5 to 6.

2

Piece 2 of 2

The rest of the roof of the mouth comes from two shelves that start to grow downward beside the tongue at about week 6. By week 8 those shelves lift up to horizontal above the tongue, in weeks 8 to 9 they meet in the middle and begin to join, and by week 12 the roof of the mouth is fully fused and closed. The lab keeps a mouse timeline too, because most experiments use mice, but for Mateo we use the human weeks.

Explore

Reading the Research

What to read
Why this source matters
This is the published evidence behind today's idea: A structure can only break during the window when it is being built, so timing the event tells the team when to look, not yet what or why.
Words to unlock first
embryocraniofacial developmentgestational weekfusioncritical window
Reading moves
  1. Skim the title and abstract first to get the gist.
  2. Circle the one sentence that states the main claim.
  3. Box the evidence the authors give for that claim.
  4. Mark one sentence that confuses you, and move on.
Stop point
You do not need the methods or statistics yet. If a sentence is about lab technique or math you have not learned, mark it and skip it.
Your output
Write one claim-evidence sentence: what this source claims, and the one piece of evidence that backs it up.

Now put it together: In one or two sentences, say what this whole reading is telling you about Mateo. Then go back to the lesson and fill in the guided notes.