Tue, Apr 20, 2027Spring (Semester 2) · Week 14Day 58 of 6780-min block

Chemo and radiation

Today's target

Compare how chemotherapy and radiation kill cancer cells and why each causes side effects.

Due today · CER Required

CER paragraph arguing which treatment (chemo or radiation) is more appropriate for a localized tumor, with apoptosis and side-effect evidence.

Your 4 steps today
  1. 1
    Do this
    Compare how chemotherapy and radiation kill cancer cells and why each causes side effects.
  2. 2
  3. 3
    Submit this
    CER: CER paragraph arguing which treatment (chemo or radiation) is more appropriate for a localized tumor, with apoptosis and side-effect evidence.
  4. 4
    Submit it here
    1. 1CMSD website. Go to clevelandmetroschools.org and click the Clever button.
    2. 2Clever. Clever opens. Sign in if it asks.
    3. 3Microsoft (district) login. Use your district Microsoft account (the one for school).
    4. 4Schoology. Open Schoology, then your class, then Assignments, and find the file named below.
    The file to submit is named: Genetics of Disease (Medical Interventions) › Biopsy, imaging, staging, chemo, radiation, targeted therapy, response, side effects. › CER
    Open Schoology
Were you absent? Jump to the make-up plan
Where this fits
Tested on (Ohio WebXam)
Genetics of Disease · 072130
PLTW lesson
MI · Chemo and radiation
WebXam domain
Bio-Molecular Technology
Evidence to produce
CER
Quick glossary
CER:
Claim, Evidence, Reasoning — make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure — the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities — you open it through Schoology.
Learn first

Minute-by-minute · 80-minute block

💡 Big idea: Killing cancer cells means disrupting cell division, which always risks collateral damage to healthy tissue.

  1. 0-8Read treatment notes; define apoptosis in margin
  2. 8-25Draw chemotherapy mechanism diagram (systemic, fast-dividers)
  3. 25-40Draw radiation mechanism diagram (targeted, DNA damage)
  4. 40-55List two side effects each; link to healthy tissue type
  5. 55-72Write CER paragraph: chemo vs. radiation for a localized tumor
  6. 72-80Peer review CER structure; submit
Mr. Mendoza's 5-minute intro
  • Both chemotherapy and radiation kill cancer, but they do it differently and hurt different bystanders.
  • Today you will diagram each mechanism and then argue which one fits a specific case.
  • The CER format you practice today is one of the highest-frequency skills on the WebXam.
  • By the end you will be able to explain to a patient why their hair may fall out.
Do this, step by step
  1. 1Read the treatment-mechanism notes in the PLTW course shell and define apoptosis.
  2. 2Diagram how chemotherapy targets fast-dividing cells throughout the body.
  3. 3Diagram how radiation damages cell DNA in a targeted area.
  4. 4List two common side effects for each and tie them to healthy fast-dividing tissue.
  5. 5Write a CER paragraph claiming which treatment fits a localized tumor and why.
You'll be able to
  • You'll be able to contrast the mechanisms of chemotherapy and radiation.
  • You'll be able to explain side effects using apoptosis and healthy-cell damage.
Know by the end
  • Chemotherapy circulates systemically and targets any rapidly dividing cell.
  • Radiation delivers focused ionizing energy to damage DNA in a defined tumor volume.
  • Side effects correlate directly to which fast-dividing healthy tissues are caught in the treatment field.
📺 Tutor me: NCI: Chemotherapy to Treat Cancer
Do the work

Your PLTW work today

Open this PLTW section today

Biopsy, imaging, staging, chemo, radiation, targeted therapy, response, side effects. · Chemo and radiation

Day 3 of this lesson. Open this exact section in myPLTW (reached through Schoology), then do the work below.

Do this: Open Activity 3.3.1 Diary of a Cancer Patient in myPLTW for Lesson 3.3 Treating Cancer and use the treatment-mechanism notes to diagram chemotherapy and radiation.

Complete

Mark the chemo-and-radiation entry complete and attach your CER paragraph.

How far to get

Biopsy and staging should be done (Tuesday); chemo/radiation diagrams and CER due today.

Upload as evidence

Both mechanism diagrams and CER paragraph submitted in the course shell.

All PLTW activities are completed inside the PLTW course environment — this page only gives direction. Submit producibles on Schoology.

The plan

Today's PLTW tracker

Check things off as you work, then submit. This tells Mr. Mendoza how you're doing so he can help the class. It does not replace turning in your producible on Schoology.

Use the code Mr. Mendoza gave you, not your name. Saved on this device.

Biopsy, imaging, staging, chemo, radiation, targeted therapy, response, side effects.Day 3 of this projectSee the full week plan
Today's PLTW target

Biopsy, imaging, staging, chemo, radiation, targeted therapy, response, side effects. · Chemo and radiation

Open Activity 3.3.1 Diary of a Cancer Patient in myPLTW for Lesson 3.3 Treating Cancer and use the treatment-mechanism notes to diagram chemotherapy and radiation.

Biopsy and staging should be done (Tuesday); chemo/radiation diagrams and CER due today.

This is how Mr. Mendoza sees the class keeping pace with PLTW. Be honest, it only helps if it is accurate.

1 · What you do today

🎯 Compare how chemotherapy and radiation kill cancer cells and why each causes side effects.

  • Read the treatment-mechanism notes in the PLTW course shell and define apoptosis.
  • Diagram how chemotherapy targets fast-dividing cells throughout the body.
  • Diagram how radiation damages cell DNA in a targeted area.
  • List two common side effects for each and tie them to healthy fast-dividing tissue.
  • Write a CER paragraph claiming which treatment fits a localized tumor and why.
2 · Turn in today

CER: CER paragraph arguing which treatment (chemo or radiation) is more appropriate for a localized tumor, with apoptosis and side-effect evidence.

Submit on Schoology

Upload by 11:29 PM for full credit.

3 · Who's doing what (team)
TaskWho
Read the treatment-mechanism notes in the PLTW course shell and define apoptosis._______
Diagram how chemotherapy targets fast-dividing cells throughout the body._______
Diagram how radiation damages cell DNA in a targeted area._______
List two common side effects for each and tie them to healthy fast-dividing tissue._______
Write a CER paragraph claiming which treatment fits a localized tumor and why._______

Working solo? Put your own name in "Who" for every row.

4 · Words I can use correctly
5 · I'm successful today when I can…
  • You'll be able to contrast the mechanisms of chemotherapy and radiation.
  • You'll be able to explain side effects using apoptosis and healthy-cell damage.
6 · Reflection & next steps
Where are you today?0/7 checked
Pick your period and code first.
Explore

Teacher-posted resources

Classroom documents for this lesson. Ones marked “Open the file” open right here; the rest are posted in Schoology. Use the label on each card to choose the right move.

Use during lessonFor: Everyone
MI Activity 3.3.1 Diary of a Cancer Patient
worksheet/handoutOpens here
Open the file

Open this when the class reaches this activity and use it to complete the required lesson artifact.

Placement rationale

Matched Cancer treatment and therapeutic choices by path:Medical-Interventions/Unit-3_How-to-Conquer-Cancer/3.3_Treating-Cancer; keywords:chemotherapy, radiation, cancer. Score 146. Visibility: student-schoology (student-facing resource; link through Schoology rather than local path).

Catch-up / reteachFor: Need extra support
MI 3.4 Progress Tracker & Study Guide
worksheet/handoutOpens here
Open the file

Use this if you were absent, got stuck, or need another pass before you submit the lesson artifact.

Placement rationale

Matched Cancer treatment and therapeutic choices by path:Medical-Interventions/Unit-3_How-to-Conquer-Cancer/3.4_Building-a-Better-Cancer-Treatment; keywords:treatment, cancer. Score 142. Visibility: student-schoology (student-facing resource; link through Schoology rather than local path).

How to get there: open the CMSD website, click Clever, sign in with your Microsoft (district) account, then open Schoology from Clever.

Words

This unit's vocabulary

biopsystagingchemotherapyradiationtargeted therapyapoptosisside effect

Tap the speaker to hear a term. Weekly vocabulary task: add two of these terms to your notebook glossary with a definition and an example in your own words.

Check yourself

WebXam practice

Tap an answer to check it · nothing is recorded or graded
Which test is used to make the definitive determination of whether cancer is present by removing a small sample of tissue?
How does radiation therapy differ from chemotherapy?
Chemotherapy causes body-wide side effects such as hair loss and bone marrow suppression because it
A tumor suppressor gene that cannot correct damage will trigger apoptosis. Apoptosis is
Check yourself

Cumulative WebXam review

A quick mixed-review pulling questions from earlier units plus today, so the WebXam material stays fresh.

Tap an answer to check it · nothing is recorded or graded
[Review: Editing the Code: Gene Therapy and Its Ethics] One major challenge that keeps gene therapy from being perfect is complete integration, which means
[Review: Molecule to Patient: Unit 2 Synthesis] A genetic counselor's main role on the health care team is to
[Review: When Cells Forget the Rules: Cancer Launch] When cancer cells break away and spread to other areas of the body, this process is called
Which test is used to make the definitive determination of whether cancer is present by removing a small sample of tissue?
Explore

Where this leads — careers

What today's skills lead to. These are real health-science careers this course builds toward. Tap one to see, on the US Department of Labor's O*NET site, what the job actually involves, what it pays, and how fast it is growing.

Safety net

What to do if you were absent

If YOU are absent

Today is individual PLTW work, so do exactly what we did in class, from home: complete the same PLTW target above, then submit your CER.

Open Schoology (CMSD) and keep going

How to get there: open the CMSD website, click Clever, sign in with your Microsoft (district) account, then open Schoology from Clever.

If MR. MENDOZA is absent

Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:

National Cancer Institute: Types of cancer treatment
Explore

Optional extra credit (async)

You've passed Unit 2, so the optional extra-credit track is open. Complete reserved-unit work from home (virtual labs included) for extra credit, all submitted on Schoology.

Open the extra-credit track
How this is graded
For: CER — CER paragraph arguing which treatment (chemo or radiation) is more appropriate for a localized tumor, with apoptosis and side-effect evidence.
  • Complete
    Every required part of the artifact is present, nothing left blank.
  • Accurate
    The science and the data are correct and match the evidence.
  • Scientific reasoning
    You explain your claim with evidence and reasoning (CER), not just an answer.
  • Professional communication
    Clear, organized, labeled, and written the way a clinician or scientist would.
  • Submitted
    Turned in the right way (Schoology for routine work) and confirmed.
Submission Zone

Drop your Tue, Apr 20, 2027 · Chemo and radiation here. Use a clear file name (your initials + project). Routine work still goes to Schoology (via the CMSD portal).

Upload a project