Mon, Mar 1, 2027Spring (Semester 2) · Week 7Day 28 of 6780-min block

Bioethics debate: research vs risk

Today's target

Debate whether growing and studying dangerous bacteria is worth the risk it carries to researchers and the public.

Due today · CER Required

Written CER on risky pathogen research: position with specific safeguards, evidence about benefit and containment risk, reasoning, and rebuttal.

Your 4 steps today
  1. 1
    Do this
    Debate whether growing and studying dangerous bacteria is worth the risk it carries to researchers and the public.
  2. 2
  3. 3
    Submit this
    CER: Written CER on risky pathogen research: position with specific safeguards, evidence about benefit and containment risk, reasoning, and rebuttal.
  4. 4
    Submit it here
    1. 1CMSD website. Go to clevelandmetroschools.org and click the Clever button.
    2. 2Clever. Clever opens. Sign in if it asks.
    3. 3Microsoft (district) login. Use your district Microsoft account (the one for school).
    4. 4Schoology. Open Schoology, then your class, then Assignments, and find the file named below.
    The file to submit is named: Genetics of Disease (Medical Interventions) › Aseptic technique, culturing, selection, resistance genes, and data reliability. › CER
    Open Schoology
Were you absent? Jump to the make-up plan
Where this fits
Tested on (Ohio WebXam)
Genetics of Disease · 072130
PLTW lesson
MI · Bioethics debate: research vs risk
WebXam domain
Bio-Molecular Technology
Evidence to produce
CER
Lab / skill
CDC Antibiotic Resistance
Quick glossary
CER:
Claim, Evidence, Reasoning — make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure — the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities — you open it through Schoology.
Learn first

Minute-by-minute · 80-minute block

💡 Big idea: How do scientists and society decide when the potential benefits of dangerous research justify the risks it creates?

  1. 0-10 minRead scenario; define biosafety level and dual-use research in notebook
  2. 10-25 minDraft CER: claim (proceed or not, and with what safeguards), reason, evidence from the scenario
  3. 25-40 minPartner exchange: find someone who weights the risk differently; record their strongest counterpoint
  4. 40-55 minWrite rebuttal; revise safeguard requirement if the counterpoint identified a real gap
  5. 55-68 minPost CER to the discussion board
  6. 68-80 minRead two classmates' CERs; leave a one-sentence response to each
Mr. Mendoza's 5-minute intro
  • In 2014, the CDC accidentally released live anthrax from a high-security lab; in 2015, smallpox vials were found in an unsecured FDA storage room.
  • These incidents show that the question is not hypothetical: lab containment failures happen, and the consequences can be catastrophic.
  • Today's debate asks where the line is between necessary risk and irresponsible danger.
  • Exit goal: a posted CER with a specific safeguard requirement, evidence about risk and benefit, and a rebuttal.
Do this, step by step
  1. 1Read the scenario: studying superbugs helps treatment but requires growing risky cultures.
  2. 2Write your Claim: should this research proceed, and with what safeguards?
  3. 3Add a Reason and Evidence weighing benefit against containment risk.
  4. 4Trade with a partner who weighs the risk differently and note their point.
  5. 5Write a Rebuttal answering it.
  6. 6Post your CER and read two classmates' positions on safeguards.
You'll be able to
  • You will be able to argue a position on risky pathogen research.
  • You will be able to weigh research benefit against safety risk.
  • You will be able to rebut an opposing view.
Know by the end
  • Biosafety levels (BSL-1 through BSL-4) define required containment procedures for different classes of pathogens.
  • Dual-use research of concern (DURC) refers to research that could be misused to threaten public health or national security.
  • Benefit-risk analysis in research ethics weighs scientific and medical gain against probability and magnitude of harm.
Do the work

Your PLTW work today

Open this PLTW section today

Aseptic technique, culturing, selection, resistance genes, and data reliability. · Bioethics debate: research vs risk

Day 1 of this lesson. Open this exact section in myPLTW (reached through Schoology), then do the work below.

Do this: Open the culturing ethics debate activity in myPLTW for Activity 1.2.3 Attack of the Superbugs and review the CER rubric.

Complete

Post your CER on the ethics of antibiotic prescribing policy and reply to at least two classmates.

How far to get

Lesson 1.2 portfolio should be submitted; this debate opens the culturing week.

Upload as evidence

CER post visible in the course discussion board.

All PLTW activities are completed inside the PLTW course environment — this page only gives direction. Submit producibles on Schoology.

The plan

Today's PLTW tracker

Check things off as you work, then submit. This tells Mr. Mendoza how you're doing so he can help the class. It does not replace turning in your producible on Schoology.

Use the code Mr. Mendoza gave you, not your name. Saved on this device.

Aseptic technique, culturing, selection, resistance genes, and data reliability.Day 1 of this projectSee the full week plan
Today's PLTW target

Aseptic technique, culturing, selection, resistance genes, and data reliability. · Bioethics debate: research vs risk

Open the culturing ethics debate activity in myPLTW for Activity 1.2.3 Attack of the Superbugs and review the CER rubric.

Lesson 1.2 portfolio should be submitted; this debate opens the culturing week.

This is how Mr. Mendoza sees the class keeping pace with PLTW. Be honest, it only helps if it is accurate.

1 · What you do today

🎯 Debate whether growing and studying dangerous bacteria is worth the risk it carries to researchers and the public.

  • Read the scenario: studying superbugs helps treatment but requires growing risky cultures.
  • Write your Claim: should this research proceed, and with what safeguards?
  • Add a Reason and Evidence weighing benefit against containment risk.
  • Trade with a partner who weighs the risk differently and note their point.
  • Write a Rebuttal answering it.
  • Post your CER and read two classmates' positions on safeguards.
2 · Turn in today

CER: Written CER on risky pathogen research: position with specific safeguards, evidence about benefit and containment risk, reasoning, and rebuttal.

Submit on Schoology

Upload by 11:29 PM for full credit.

3 · Who's doing what (team)
TaskWho
Read the scenario: studying superbugs helps treatment but requires growing risky cultures._______
Write your Claim: should this research proceed, and with what safeguards?_______
Add a Reason and Evidence weighing benefit against containment risk._______
Trade with a partner who weighs the risk differently and note their point._______
Write a Rebuttal answering it._______
Post your CER and read two classmates' positions on safeguards._______

Working solo? Put your own name in "Who" for every row.

4 · Words I can use correctly
5 · I'm successful today when I can…
  • You will be able to argue a position on risky pathogen research.
  • You will be able to weigh research benefit against safety risk.
  • You will be able to rebut an opposing view.
6 · Reflection & next steps
Where are you today?0/9 checked
Pick your period and code first.
Explore

Teacher-posted resources

Classroom documents for this lesson. Ones marked “Open the file” open right here; the rest are posted in Schoology. Use the label on each card to choose the right move.

Catch-up / reteachFor: Need extra support
PLTW-MI Daily Activity Tracker Unit 1 (Final)
worksheet/handoutOpens here
Open the file

Use this if you were absent, got stuck, or need another pass before you submit the lesson artifact.

Placement rationale

Matched Culturing, aseptic technique, superbugs by path:Medical-Interventions/Unit-1_How-to-Fight-Infection/00_Unit-Overview. Score 126. Visibility: student-schoology (student-facing resource; link through Schoology rather than local path).

Use during lessonFor: Everyone
MI Activity 1.2.1 Antibiotic Therapy
worksheet/handoutOpens here
Open the file

Open this when the class reaches this activity and use it to complete the required lesson artifact.

Placement rationale

Matched Culturing, aseptic technique, superbugs by path:Medical-Interventions/Unit-1_How-to-Fight-Infection/1.2_Antibiotic-Treatment. Score 126. Visibility: student-schoology (student-facing resource; link through Schoology rather than local path).

How to get there: open the CMSD website, click Clever, sign in with your Microsoft (district) account, then open Schoology from Clever.

Lab day

Lab & supplies

Bring / set up
Agar plates (or culturing simulation)Inoculating loopBunsen burner or sterile single-use loopsBacterial sample or brothIncubatorLabeling marker and tape
CDC Antibiotic Resistance
Words

This unit's vocabulary

aseptic techniqueculturecolonyinhibitionmutationhorizontal gene transfer

Tap the speaker to hear a term. Weekly vocabulary task: add two of these terms to your notebook glossary with a definition and an example in your own words.

Check yourself

WebXam practice

Tap an answer to check it · nothing is recorded or graded
What is the purpose of a four-quadrant streak plate when inoculating a bacterial culture?
On a transformation plate you see the expected white E. coli colonies plus several fuzzy gray-green colonies. What does this most likely indicate, and what should you do?
You inoculate selective LB-ampicillin broth with E. coli that you transformed with a plasmid carrying the ampicillin-resistance gene. What outcome do you expect after overnight growth at 37 degrees Celsius?
A single random mutation gives one bacterium a stronger cell wall that resists an antibiotic. How does this lead to a resistant infection?
Check yourself

Cumulative WebXam review

A quick mixed-review pulling questions from earlier units plus today, so the WebXam material stays fresh.

Tap an answer to check it · nothing is recorded or graded
[Review: Getting ready to test: serial dilutions and the ELISA setup] A technician makes a serial dilution starting with 100 ng/mL of antigen, transferring equal parts antigen and water at each step. What is the concentration after the first two dilutions?
[Review: Reading the color: running an ELISA and trusting your controls] An ELISA result is read simply as a color change with no number attached. This kind of observed, non-measurable result is called what?
[Review: How antibiotics fight bacteria and why resistance is rising] Which mechanism is the most common way bacteria share plasmids carrying antibiotic-resistance genes?
What is the purpose of a four-quadrant streak plate when inoculating a bacterial culture?
Explore

Where this leads — careers

What today's skills lead to. These are real health-science careers this course builds toward. Tap one to see, on the US Department of Labor's O*NET site, what the job actually involves, what it pays, and how fast it is growing.

Safety net

What to do if you were absent

Today was a debate — do this instead

If you are away, post a full CER on whether risky pathogen research should proceed and reply to one classmate with a rebuttal.

Then submit your CER on Schoology.

If MR. MENDOZA is absent

Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:

CDC Antibiotic Resistance
How this is graded
For: CER — Written CER on risky pathogen research: position with specific safeguards, evidence about benefit and containment risk, reasoning, and rebuttal.
  • Complete
    Every required part of the artifact is present, nothing left blank.
  • Accurate
    The science and the data are correct and match the evidence.
  • Scientific reasoning
    You explain your claim with evidence and reasoning (CER), not just an answer.
  • Professional communication
    Clear, organized, labeled, and written the way a clinician or scientist would.
  • Submitted
    Turned in the right way (Schoology for routine work) and confirmed.
Submission Zone

Drop your Mon, Mar 1, 2027 · Bioethics debate: research vs risk here. Use a clear file name (your initials + project). Routine work still goes to Schoology (via the CMSD portal).

Upload a project