Pedigree logic
Fri, Oct 16, 2026 · Week 8 · Genetics of Disease (Medical Interventions)
Today's goal: Use pedigree symbols to track an inherited trait and identify carriers across generations.
This is a model of the work you should turn in today. Use it to check your own: match the structure and the level of detail, do not copy it. Your data and wording should be your own.
Parallel family, not your case: Generation I, an affected father and an unaffected mother. Generation II, their affected son, their affected daughter and their unaffected daughter. Generation III, the affected son and his affected wife have an affected son and an unaffected daughter.
I drew the family using standard symbols: squares for males, circles for females, filled-in shapes for affected individuals, and a horizontal line for each mating.
Mode of inheritance: In this parallel family the trait is autosomal dominant.
Evidence from the pattern: Every affected child has at least one affected parent, and the trait shows up in all three generations, which fits a dominant allele. Generation III rules out recessive, because two affected parents have an unaffected daughter. If the trait were recessive, both parents would be aa, and every child of theirs would be aa and affected. In Generation I an affected father and an unaffected mother have an affected son. A father gives his son a Y chromosome, not an X, so the son's allele came through an autosome. The same father has an unaffected daughter, and an affected father gives his X to every daughter, so the trait is not X-linked dominant either. That makes it autosomal dominant.
Carriers I circled: None. With a dominant trait, anyone who carries the allele shows it, so there is no unaffected carrier to circle. (A real family can break this rule when an allele does not always show, and a pedigree alone cannot tell you that.) Instead I labeled genotypes. The Generation I father must be Aa, not AA, because his unaffected daughter is aa and got one a from him. The same logic makes the affected son and his affected wife both Aa, because their unaffected daughter is aa.
Your family can give a different answer. Test each pattern against every parent and child in your own pedigree before you call it.
| Individual | Symbol | Status |
|---|---|---|
| Gen I father | filled square | affected (Aa) |
| Gen II son | filled square | affected (Aa) |
| Gen II son's wife | filled circle | affected (Aa) |
| Gen II daughter | open circle | unaffected (aa) |
| Gen III son | filled square | affected (AA or Aa) |
| Gen III daughter | open circle | unaffected (aa) |
This model shows the level of evidence and organization needed to complete: Completes the pedigree analysis: a correctly drawn three-generation pedigree with carriers circled, the mode of inheritance stated, and one sentence of evidence from the pattern.
- Name the variables and include units.
- Enter observations without changing the raw values.
- Check labels, calculations, and patterns before interpreting the data.
Keep the structure. Replace the question, facts, measurements, and evidence. Then recheck units, vocabulary, and whether the conclusion goes beyond the evidence.
Also due today: Submit your pedigree and inheritance call as one PDF to Schoology assignment Wk8 Data table: Pedigree logic.
Turn in: Completed three-generation pedigree with carriers circled, mode of inheritance stated, and one sentence of evidence.
Go to Schoology to turn this in.
Submit one PDF. Schoology attaches your name to your upload; on the page itself, write your period and code. Name the file: FirstName LastName - Assignment Title - YYYY-MM-DD.pdf.
Open Schoology PDF upload helpIf you cannot get in, see Mr. Mendoza. Do not skip the work.
Claim ceiling: Today's evidence supports a classroom claim about pedigree logic. It cannot prove causation, diagnose a real patient, or justify action outside this room.
One exam-style question that uses exactly what you practiced today. Try it before you reveal the answer, then read why each choice is right or wrong.
Tap an answer to see the full explanation. Nothing is recorded or graded.
It builds this reusable test skill: Determining mode of inheritance from a pedigree pattern.
- Name the concept or data pattern being tested.
- Cross out choices that violate that rule or the evidence.
- Justify the best remaining choice before checking the answer.

