Human Anatomy & Physiology (Human Body Systems)
Unit 2: Unit 2: Communication (Nervous & Endocrine)HBS 2.3Human Body Systems: investigation & data analysis

State limitations

Name what could weaken a result: small sample size, measurement error, and confounders: and what the data still can't show.

Builds on (2 levels back)inferred · high confidence
  • Sample vs. whole group: A limitation often comes from testing only a few cases, so you must see how a sample relates to the whole group.
  • What a measurement supports: Stating limits means knowing which claims the data can and cannot back up.

Prerequisites are inferred: pending teacher review.

Re-learn the skill with worked practice and clear examples.

State limitations by naming small sample size, measurement error, and confounders: and by saying what the data still can't show.

Step 1: Check the sample size
Few cases (here, a handful of samples) make it risky to generalize to a whole population. More samples give a more trustworthy result.
Step 2: Check measurement error
Every reading has some error: a test strip read by eye, or a tool that is off by a little. A single reading might not equal the true value, so repeats matter.
Step 3: Check confounders and reach
A confounder is a second factor that could explain the result (old pipes, time of day water sat). Also state what the data can't show: one reading at one tap can't prove a health effect or speak for other buildings.
Practice

A team measured lead (ppb) in four water samples from one home, shown below, and concluded the city's water is unsafe. Which is the strongest limitation of that conclusion?

Reviewed
SampleLead concentration (ppb)
16
29
37
410
A two-column table listing four water samples and the measured lead concentration in parts per billion for each.
  1. A.The samples were measured in the wrong units
  2. B.Four samples from one home can't represent a whole city's water
  3. C.Lead is not harmful at any level
  4. D.A data table cannot hold lead measurements
Show the worked solution ▾

Answer: B. Four samples from one home can't represent a whole city's water

  1. Step 1: Compare sample to claim: Only four samples, all from one home, were taken. The conclusion is about the entire city.
  2. Step 2: Name the limitation: Such a small, single-location sample can't be generalized to every home in the city: that is the strongest limitation.

Why it's right: Four samples from one home is a small, single-site sample, so generalizing to the whole city is the strongest limitation here.

Why the others miss:
  • A: The units (ppb) are appropriate for lead in water.
  • C: Whether lead is harmful is not the flaw in this study's reasoning about sampling.
  • D: A data table is a fine place to record lead measurements.

Aligned to HBS investigation: limitations · reading level ~grade 9

Where you'd see this
  • A 'Limitations' section lists small n, measurement error, and possible confounders so readers weight the conclusion fairly.
Video library
Watch: State limitations
Correlation Doesn't Equal Causation: Crash Course Statistics #8
CrashCourse · 11 min
Guided notes

Fill these in as you work through the lesson.

Big idea: Every investigation has limits: a small sample, measurement error, or hidden confounders can weaken what the data is allowed to claim.
Key terms: write the meaning
  • Limitation (a reason the result might not be trustworthy or general):  
  • Sample size (how many cases were tested):  
  • Measurement error (how far a reading can be off from the true value):  
  • Confounder (a second factor that could explain the result):  
  • Generalize (to extend a finding beyond the cases tested):  
The rule

A small   makes it risky to   the result to everyone. Measurement   means a single reading might not be exact, and a hidden   could be the real cause.

Check yourself
  1. Why is a result from only three water samples hard to trust for a whole city? 
  2. Name one source of measurement error when reading a lead test. 
  3. Give one thing a single lead reading at one tap still can't tell you. 
Work one example

A team measured lead in three tap-water samples from one building and concluded the whole city's water is unsafe. List three limitations of that conclusion.