Genetics of Disease (Medical Interventions)
Unit 3: Unit 3.2 to 3.4 Treating CancerMI 3.2-3.4Biotechnology Research and Experiments

Compare Treatment Options

Use cancer evidence to compare treatment options from cell regulation through treatment planning.

Builds on (2 levels back)inferred · high confidence
  • Sign vs. symptom: Clinical data mixes measured findings with patient-reported history.
  • Normal range comparison: Students need a reference range or baseline to tell whether a value is concerning.

Prerequisites are inferred: pending teacher review.

Re-learn the skill with worked practice and clear examples.

Compare treatments by two things: does it reach one spot or the whole body, and what side effects does it cause? Then pick the one that fits the cancer.

Step 1: Read the comparison table
The table lists four treatments, how each reaches the cancer (local or systemic), and its main side effects.
Step 2: Match the treatment to the cancer
A cancer in one spot can be cut out or beamed (local). A cancer that has spread needs something that travels everywhere (systemic).
Step 3: Weigh the side effects
Chemotherapy hits healthy fast-growing cells too, so it causes hair loss and nausea. Targeted therapy aims at a marker, so it usually has fewer whole-body side effects: but only if the cancer has that marker.
Practice

Use the table. A patient has cancer that has spread to several organs. Which treatment can reach cancer cells all over the body?

Approved
TreatmentHow it reaches the cancerMain side effects
SurgeryLocal: cuts out the tumor in one spotPain and risk from the operation; only helps where it cuts
RadiationLocal: a beam aimed at one spotSkin and tissue damage near the beam
ChemotherapySystemic: travels in the blood to the whole bodyHair loss, nausea, low blood counts (hits healthy fast-growing cells too)
Targeted therapySystemic but aimed at one marker on cancer cellsFewer whole-body effects, but only works if the cancer has that marker
Comparison of four cancer treatments. Surgery is local with operation side effects. Radiation is local with skin and tissue damage near the beam. Chemotherapy is systemic with hair loss, nausea, and low blood counts. Targeted therapy is systemic but aimed at a specific marker with fewer whole-body side effects.
  1. A.Surgery, because it removes the tumor
  2. B.Radiation, because the beam is strong
  3. C.Chemotherapy, because it is systemic and travels in the blood
  4. D.Surgery and radiation together
Show the worked solution ▾

Answer: C. Chemotherapy, because it is systemic and travels in the blood

  1. Step 1: Find the spread: The cancer is in several organs, not one spot, so a one-spot treatment can't reach it all.
  2. Step 2: Use the table's reach column: Surgery and radiation are listed as local. Chemotherapy is listed as systemic: it travels in the blood to the whole body.

Why it's right: Chemotherapy is systemic, so it reaches cancer cells throughout the body: the only choice that fits cancer that has spread.

Why the others miss:
  • A: Surgery is local; it only treats the one spot it removes.
  • B: Radiation is local; the beam only hits where it is aimed.
  • D: Both of these are local and still can't reach cancer that has spread everywhere.

Aligned to BRE: compare treatment options · reading level ~grade 9

Where you'd see this
  • In Unit 3.2 to 3.4 Treating Cancer, this skill turns class evidence into a result another person can check.
Video library
Watch: Compare Treatment Options
How does chemotherapy work? - Hyunsoo Joshua No
TED-Ed · 5 min
Guided notes

Fill these in as you work through the lesson.

Big idea: Cancer treatments differ in two big ways: whether they treat one spot (local) or the whole body (systemic), and what side effects they cause. You pick the one that fits the cancer.
Key terms: write the meaning
  • Local treatment (treats one spot only):  
  • Systemic treatment (travels through the whole body):  
  • Targeted therapy (aimed at a specific marker on cancer cells):  
  • Metastasis (cancer that has spread to other places):  
  • Side effect (harm a treatment causes besides killing cancer):  
The rule

Surgery and radiation are   treatments (one spot). Chemotherapy is   because it travels through the whole body. If cancer has spread, you usually need a   treatment.

Check yourself
  1. Name one local treatment and one systemic treatment. 
  2. Why does chemotherapy cause hair loss and nausea but a targeted drug usually does not? 
  3. If a cancer has spread to several organs, why won't surgery alone cure it? 
Work one example

A tumor sits in one spot in the breast and has NOT spread. Compare surgery and chemotherapy using the table, then say which fits this cancer and why.