Genetics of Disease (Medical Interventions)
Reliability and limitation checklist
Reliability and limitation checklist
Unit 2: Unit 2 Synthesis (Molecule to Patient)MI 2Biotechnology Research and Experiments
Evaluate Validity Reliability
Judge whether evidence is trustworthy enough and name what limits the claim.
Builds on (2 levels back)inferred · high confidence
- Read a data table: Students need to find values, labels, and units before calculating or graphing.
- Fair-test logic: Variables and controls make comparisons meaningful.
Prerequisites are inferred: pending teacher review.
Re-learn the skill with worked practice and clear examples.
Judge whether evidence is trustworthy enough and name what limits the claim.
Step 1: Learn the key
Reliable evidence has a clear [blank], working [blank], and repeatable results; a limitation says what is still [blank].
| Reliability check | Stronger evidence |
|---|---|
| Repeated result | same pattern appears again |
| Working controls | positive and negative controls behave |
| Clear source | sample identity is known |
| Large enough sample | not based on one case |
Step 2: Use the model
Read the figure, table, control, range, or protocol before choosing an answer.
Step 3: Name the limit
Say what the evidence can support and what it cannot prove yet.
Practice
Use the reliability checklist. Which evidence is weakest?
Reviewed| Reliability check | Stronger evidence |
|---|---|
| Repeated result | same pattern appears again |
| Working controls | positive and negative controls behave |
| Clear source | sample identity is known |
| Large enough sample | not based on one case |
- A.One unlabeled sample with no control
- B.Three repeated results with controls
- C.A sample with clear source and expected controls
- D.A test repeated by a second team
Show the worked solution ▾
Answer: A. One unlabeled sample with no control
- Step 1: Check sample identity: Unlabeled means unclear source.
- Step 2: Check controls: No control weakens interpretation.
Why it's right: An unlabeled sample without controls is weakest.
Why the others miss:
- B: This is stronger.
- C: This is stronger.
- D: Independent repeat is stronger.
Aligned to Biotechnology Research and Experiments · reading level ~grade 9
Where you'd see this
- In Unit 2 Synthesis (Molecule to Patient), this skill turns class evidence into a result another person can check.
Video library
Watch: Evaluate Validity Reliability
Validity, reliability and accuracy explained
PhysicsHigh · 8 min
Guided notes
Fill these in as you work through the lesson.
Big idea: Judge whether evidence is trustworthy enough and name what limits the claim.
Key terms: write the meaning
- Reliability (how trustworthy evidence is):
- Validity (whether the test measures the right thing):
- Limitation (weakness or missing information):
- Repeatability (same result when repeated):
The rule
Reliable evidence has a clear , working , and repeatable results; a limitation says what is still .
Check yourself
- Did controls work?
- Was the sample identity clear?
- What evidence is missing?
Work one example
A result is positive but has one trial and no control. Name the limitation and next step.