Mapping the Failure, Which Step Breaks for a Cleft Lip Versus a Cleft Palate
Take the reading one piece at a time. For each piece: read it once, underline the sentence that says what happens, then look up any word in the list. Tap a word to see its definition.
Piece 1 of 5
Match each cleft to the build step that failed (DATA_TABLES.md contrast card; PMID:26589921; PMID:16282779).
Piece 2 of 5
Patient A, cleft LIP only: the lip and gum are clefted but the palate roof is intact. Step 1, lip fusion (medial nasal plus maxillary), failed in weeks 4 to 6.
Piece 3 of 5
Patient B, cleft PALATE only: the roof of the mouth is clefted but the lip is intact. One of steps 2 to 4 (palate growth, elevation, or fusion) failed in weeks 6 to 12.
Piece 4 of 5
Patient C, cleft LIP AND palate: both the lip and the roof are clefted. Step 1 fails early and also derails the later palate steps, weeks 4 to 12.
Piece 5 of 5
Notice: each is a failure of a fusion or growth step in the face. None lists a brain, heart, or limb defect. The failure is local to the face-building steps.
Reading the Research
- Skim the title and abstract first to get the gist.
- Circle the one sentence that states the main claim.
- Box the evidence the authors give for that claim.
- Mark one sentence that confuses you, and move on.
Now put it together: In one or two sentences, say what this whole reading is telling you about Mateo. Then go back to the lesson and fill in the guided notes.