Negative feedback model build
Tue, Apr 6, 2027 · Week 12 · Human Anatomy & Physiology (Human Body Systems)
Today's goal: Students will build and run a physical model of blood-glucose negative feedback involving insulin and glucagon.
What a finished product looks like
This is a model of the work you should turn in today. Use it to check your own: match the structure and the level of detail, do not copy it. Your data and wording should be your own.
Negative feedback loop for blood glucose (set point about 90 mg/dL):
Meal scenario (glucose rises):
- Blood glucose goes up.
- Pancreas releases insulin.
- Insulin moves glucose into cells, so blood glucose falls back toward the set point.
Fasting scenario (glucose falls):
- Blood glucose goes down.
- Pancreas releases glucagon.
- Glucagon releases stored glucose from the liver, so blood glucose rises back toward the set point.
Why this is negative feedback: each response opposes the change that triggered it (high glucose triggers lowering, low glucose triggers raising), pulling the variable back to the set point.
Also due today: Submit your loop diagram to the Schoology assignment for HBS Endocrine Day 3.
WebXam problem for today's skill
One exam-style question that uses exactly what you practiced today. Try it before you reveal the answer, then read why each choice is right or wrong.
Tap an answer to see the full explanation. Nothing is recorded or graded.

