Principles of Biomedical Technology (Principles of Biomedical Science)
Unit 3: Unit 3.1 Outbreak EvidencePBS 3.1Biotechnology Research and Experiments

Build A Line List

Use infection evidence to build a line list step by step.

Builds on (2 levels back)inferred · high confidence
  • Transmission basics: Outbreak work depends on agent, host, route, time, and place.
  • Case definition: Students need a rule for who counts as a case before counting cases.

Prerequisites are inferred: pending teacher review.

Re-learn the skill with worked practice and clear examples.

Use infection evidence to build a line list step by step.

Step 1: Learn the key
Track the , route of transmission, time pattern, and exposed before making an outbreak claim.
CaseSymptomOnsetExposure
AcrampsTue 8 PMcafeteria
BcrampsTue 9 PMcafeteria
Cnone--no cafeteria
Outbreak line list
Step 2: Use the model
Read the figure, table, control, range, or protocol before choosing an answer.
Step 3: Name the limit
Say what the evidence can support and what it cannot prove yet.
Practice

Use the infection figure/table. Which evidence best supports a shared-source outbreak?

Reviewed
CaseSymptomOnsetExposure
AcrampsTue 8 PMcafeteria
BcrampsTue 9 PMcafeteria
Cnone--no cafeteria
Outbreak line list
  1. A.Several cases share the same exposure and close onset times
  2. B.A large total case count, even when the exposures are all different
  3. C.Cases with onset dates spread evenly over six weeks
  4. D.One person is much sicker than the others, with no exposure recorded
Show the worked solution ▾

Answer: A. Several cases share the same exposure and close onset times

  1. Step 1: Find shared exposure: A shared source means cases have a common exposure.
  2. Step 2: Check timing: Close onset times strengthen the pattern.

Why it's right: Shared exposure plus close timing supports a shared-source outbreak.

Why the others miss:
  • B: A big count with different exposures points to many sources, not one.
  • C: Onsets spread evenly over weeks fit person-to-person spread, not one source.
  • D: How sick one person is does not show that other people shared a source.

Aligned to Biotechnology Research and Experiments · reading level ~grade 9

Of 40 people who ate at the cafeteria, 10 fell ill. Of 60 people who did not eat there, 3 fell ill. What is the attack rate in each group?

Reviewed
  1. A.25% among those who ate there and 5% among those who did not
  2. B.25% among those who ate there and 20% among those who did not
  3. C.40% among those who ate there and 60% among those who did not
  4. D.10% among those who ate there and 3% among those who did not
Show the worked solution ▾

Answer: A. 25% among those who ate there and 5% among those who did not

  1. Step 1: Divide the exposed group: 10 ill out of 40 exposed is 10 divided by 40, which is 0.25.
  2. Step 2: Divide the unexposed group: 3 ill out of 60 unexposed is 3 divided by 60, which is 0.05.
  3. Step 3: Read as percentages: 0.25 is 25% and 0.05 is 5%.

Why it's right: An attack rate is the ill divided by the total in that group. 10 of 40 is 25% and 3 of 60 is 5%.

Why the others miss:
  • B: 3 of 60 is 5%, not 20%.
  • C: 40 and 60 are the group sizes, not the share of each group that fell ill.
  • D: These are the raw counts of ill people, not shares of each group.

Aligned to Biotechnology Research and Experiments · reading level ~grade 10

Where you'd see this
  • In Unit 3.1 Outbreak Evidence, this skill turns class evidence into a result another person can check.
Video library
Watch: Build A Line List
CDC NERD Academy Student Quick Learn: How is an outbreak investigated?
Centers for Disease Control and Prevention (CDC) · 6 min
Guided notes

Fill these in as you work through the lesson.

Big idea: Use infection evidence to build a line list step by step.
Key terms: write the meaning
  • Pathogen (disease-causing agent):  
  • Transmission (how a pathogen spreads):  
  • Reservoir (where pathogen lives):  
  • Case (person who fits outbreak definition):  
The rule

Track the  , route of transmission, time pattern, and exposed   before making an outbreak claim.

Check yourself
  1. Who fits the case definition? 
  2. What exposure do cases share? 
  3. What timing pattern appears? 
Work one example

Use the infection diagram or line list to practice build a line list.