Applied Mathematics for Science
CoreQuantitative reasoning: units & notation

Scientific Units & Scientific Notation

Learn the standard units science uses, what metric prefixes mean, and how to write very large and very small biology numbers cleanly with powers of ten.

Why this matters

Biology numbers are extreme. One drop of blood holds millions of cells, the human genome is about three billion base pairs, and a drug can act at a concentration of a few millionths of a gram per liter. Writing all those zeros by hand is slow and easy to get wrong, so scientists agree on two things: a shared set of units (the SI system) and a compact way to write numbers (scientific notation). Lab technicians label every tube in milliliters and micrograms so no one confuses a safe dose with a lethal one. Geneticists report a genome as 3 x 10 to the 9th power base pairs instead of counting nine zeros. Pharmacists read a concentration in mg per mL and must know that milli means one thousandth before they draw up a syringe. Epidemiologists compare case counts written in scientific notation so a city of millions lines up cleanly next to a town of thousands. Master units and scientific notation and you can read, record, and check biology data without drowning in zeros.

Standards this builds
  • Common Core · HSN-Q.A.1Use units as a way to understand problems; choose and interpret the units and the level of accuracy that fit a measurement.
  • Common Core · HSN-RN.AWork fluently with powers and exponents, including expressing and comparing numbers written with powers of ten.
  • Ohio · Ohio HS N.Q.1Reason quantitatively and use units consistently when recording, reporting, and interpreting scientific measurements.
  • NGSS · SEP-5Using Mathematics and Computational Thinking: use appropriate units and scientific notation to record and compare quantities across many orders of magnitude.
  • AP · AP Bio SP 6 (Quantitative)Work with quantities and units, including very large and very small values, when analyzing and communicating biological data.
Builds on (2 levels back)inferred · high confidence
  • Read and move a decimal point by place value: Scientific notation is all about counting how many places the decimal moves, so students must track place value confidently.
  • Understand powers of ten (10^3 = 1000, 10^-3 = 1/1000): Prefixes and scientific notation both use positive and negative powers of ten, so students must know what an exponent means.
  • Read a measurement as a number plus a unit: You cannot pick a prefix or a unit for a number you cannot name, so students must separate the number from its label first.

Prerequisites are inferred: pending teacher review.

Re-learn the skill with worked practice and clear examples.

Use the metric prefix ladder to move between sized units, and use scientific notation to write very large and very small numbers cleanly. To convert to scientific notation, put one nonzero digit in front of the decimal, then count how many places you moved it: moving left gives a positive exponent, moving right gives a negative exponent.

Step 1: Read the prefix ladder
The common prefixes line up as steps on a ladder, each a power of ten apart. From biggest to smallest: kilo (1000), the base unit (1), centi (one hundredth), milli (one thousandth), micro (one millionth), nano (one billionth). Going down the ladder makes the unit smaller, so the number of those units in a fixed amount gets larger.
A vertical prefix ladder from kilo (10^3) at the top through the base unit (10^0), centi (10^-2), milli (10^-3), micro (10^-6), down to nano (10^-9), labeled bigger at the top and smaller at the bottom.
Step 2: Write a big number in scientific notation
Take 3,200,000. Move the decimal so exactly one nonzero digit sits in front of it: 3.2. Count the places you moved it to the left: 6 places. Because you moved left, the exponent is positive, so 3,200,000 = 3.2 x 10^6.
Step 3: Write a small number in scientific notation
Take 0.00042. Move the decimal so one nonzero digit sits in front of it: 4.2. Count the places you moved it to the right: 4 places. Because you moved right, the exponent is negative, so 0.00042 = 4.2 x 10^-4.
Practice

Using the prefix ladder, how many milligrams (mg) are in 1 gram (g)? Use the fact that milli means 10^-3.

Reviewed
The gram (10^0) connected by an arrow down three steps to the milligram (10^-3 = 1/1000).
  1. A.10 mg
  2. B.100 mg
  3. C.1000 mg
  4. D.10,000 mg
Show the worked solution ▾

Answer: C. 1000 mg

  1. Step 1: Find the gap on the ladder: The gram is at 10^0 and the milligram is at 10^-3, so a milligram is 1000 times smaller than a gram.
  2. Step 2: Count the small units: If each milligram is one thousandth of a gram, it takes 1000 of them to make one whole gram.

Why it's right: The milligram sits three steps below the gram (10^-3), so 1 g = 1000 mg.

Why the others miss:
  • A: 10 is only one step down (deci), not three steps to milli.
  • B: 100 is only two steps down (centi), not three steps to milli.
  • D: 10,000 is four steps of ten, which overshoots milli by one power of ten.

Aligned to Ohio HS N.Q.1: use metric prefixes · reading level ~grade 9

A blood sample is counted as 5,600,000 white blood cells. Write this number in scientific notation.

Reviewed
  1. A.5.6 x 10^5
  2. B.5.6 x 10^6
  3. C.56 x 10^5
  4. D.5.6 x 10^-6
Show the worked solution ▾

Answer: B. 5.6 x 10^6

  1. Step 1: Place the decimal: Move the decimal so exactly one nonzero digit is in front: 5.6.
  2. Step 2: Count the places: The decimal moved 6 places to the left, and moving left makes the exponent positive, so the answer is 5.6 x 10^6.

Why it's right: Moving the decimal 6 places left turns 5,600,000 into 5.6 with a positive exponent of 6, so 5,600,000 = 5.6 x 10^6.

Why the others miss:
  • A: This is only 560,000; the decimal was moved just 5 places.
  • C: The front number must be between 1 and 10, and 56 is not.
  • D: A negative exponent would mean a tiny number less than one, but 5,600,000 is large.

Aligned to Common Core HSN-RN.A: scientific notation for large numbers · reading level ~grade 9

A drug concentration is measured as 0.000018 grams per liter. Write 0.000018 in scientific notation.

Reviewed
  1. A.1.8 x 10^-4
  2. B.1.8 x 10^-5
  3. C.1.8 x 10^5
  4. D.18 x 10^-6
Show the worked solution ▾

Answer: B. 1.8 x 10^-5

  1. Step 1: Place the decimal: Move the decimal so one nonzero digit is in front: 1.8.
  2. Step 2: Count the places: The decimal moved 5 places to the right, and moving right makes the exponent negative, so the answer is 1.8 x 10^-5.

Why it's right: Moving the decimal 5 places right turns 0.000018 into 1.8 with a negative exponent of 5, so 0.000018 = 1.8 x 10^-5.

Why the others miss:
  • A: This is 0.00018; the decimal was moved only 4 places.
  • C: A positive exponent would make the number large, but 0.000018 is tiny.
  • D: The front number must be between 1 and 10, and 18 is not.

Aligned to Common Core HSN-RN.A: scientific notation for small numbers · reading level ~grade 9

Where you'd see this
  • A lab tech writes a bacterial count of 8,300,000 colonies as 8.3 x 10^6 so it fits neatly in the data table.
  • A student converts a stock solution of 0.25 L into 250 mL to match the graduated cylinder markings.
  • A researcher records a protein concentration of 0.000045 g/mL as 4.5 x 10^-5 g/mL for the report.
Video library
Watch: writing big and small numbers with powers of ten
Scientific Notation: Introduction
Tyler DeWitt · 13:56
Watch: what kilo, centi, milli, micro, and nano mean
Metric system: units of distance | 4th grade | Khan Academy
Khan Academy · 6:56
Extension: negative exponents and comparing sizes
Scientific Notation - Multiplication and Division
The Organic Chemistry Tutor · 10:28
Guided notes

Fill these in as you work through the lesson.

Big idea: Science uses shared SI units and metric prefixes to size measurements, and scientific notation to write very large and very small biology numbers cleanly with powers of ten.
Key terms: write the meaning
  • SI base unit (the standard unit for a quantity, like meter, kilogram, second):  
  • Metric prefix (a word piece that multiplies a unit by a power of ten):  
  • Scientific notation (a value between 1 and 10 times a power of ten):  
  • Exponent (the power of ten; positive is big, negative is small):  
The rule

To write a number in scientific notation, put one nonzero digit in front of the decimal and count the places you moved it: moving   gives a positive exponent, and moving   gives a   exponent.

Check yourself
  1. Name the five SI base units in this lesson and the quantity each one measures. 
  2. On the prefix ladder, how many powers of ten separate milli from micro, and which one is smaller? 
  3. Explain how the sign of the exponent tells you whether a number is large or small. 
Work one example

Write 3,200,000 in scientific notation. Put one nonzero digit in front of the decimal to get 3.2, then count the places you moved the decimal to the left, which is 6, so 3,200,000 = 3.2 x 10^____.

 
Illustrated glossary

The vocabulary of this topic, shown in the way you will meet it.

SI base unit
One of the standard units science agrees to measure with, such as the meter for length, kilogram for mass, second for time, mole for amount of a substance, and kelvin for temperature.
QuantitySI base unitSymbol
Lengthmeterm
Masskilogramkg
Timeseconds
Amount of substancemolemol
TemperaturekelvinK
A table of five SI base units: meter (length), kilogram (mass), second (time), mole (amount), and kelvin (temperature).
In context: When a lab tech records a reaction time in seconds and a sample mass in kilograms, every scientist reading the data knows exactly what was measured because those are SI base units.
Metric prefix
A word piece added in front of a unit that multiplies it by a power of ten, such as kilo (times 1000) or milli (divided by 1000).
The prefix milli (divide by 1000) plus the base unit liter equals the milliliter, which is one thousandth of a liter.
In context: The prefix milli in milliliter tells you a milliliter is one thousandth of a liter, so 500 mL is half of a 1 L bottle.
Scientific notation
A way to write a number as a value between 1 and 10 multiplied by a power of ten, so very large or very small numbers stay short.
The number 3,200,000 written as 3.2 times ten to the sixth power, with the exponent 6 marking six decimal places moved.
In context: A geneticist writes the human genome as 3 x 10 to the 9th power base pairs instead of writing 3,000,000,000, which is faster and harder to miscount.
Exponent (power of ten)
The small raised number that tells how many times to multiply or divide by ten; a positive exponent makes a number bigger, a negative one makes it smaller.
In context: In 4.2 x 10 to the negative 4th power, the negative exponent tells a chemist the real number is tiny, 0.00042, a very small concentration.
Order of magnitude
A factor of ten difference in size; each step up or down the metric ladder or each change of one in the exponent is one order of magnitude.
In context: A cell about 10 micrometers wide and a virus about 0.1 micrometers wide differ by two orders of magnitude, which is why you need a stronger microscope to see the virus.