Fri, Dec 4, 2026Fall (Semester 1) · Week 15Day 67 of 7080-min block

Innate and adaptive immunity

Today's target

Students will distinguish innate from adaptive immunity using teacher notes and the PLTW online task.

Due today · Vocabulary task Required

Lymphatic system body diagram with key nodes and vessels labeled, plus written definitions of antigen, antibody, and lymphocyte in your own words.

Your 4 steps today
  1. 1
    Do this
    Students will distinguish innate from adaptive immunity using teacher notes and the PLTW online task.
  2. 2
  3. 3
    Submit this
    Vocabulary task: Lymphatic system body diagram with key nodes and vessels labeled, plus written definitions of antigen, antibody, and lymphocyte in your own words.
  4. 4
    Submit it here
    1. 1CMSD website. Go to clevelandmetroschools.org and click the Clever button.
    2. 2Clever. Clever opens. Sign in if it asks.
    3. 3Microsoft (district) login. Use your district Microsoft account (the one for school).
    4. 4Schoology. Open Schoology, then your class, then Assignments, and find the file named below.
    The file to submit is named: Human Anatomy & Physiology (Human Body Systems) › Unit 3.2 Body Guards: Skin/accessory organs, lymphatic and immune systems, pathogens, immune cells, antigen response. › Vocabulary task
    Open Schoology
Were you absent? Jump to the make-up plan
Where this fits
Tested on (Ohio WebXam)
Human Anatomy and Physiology · 072040
PLTW lesson
HBS · Innate and adaptive immunity
WebXam domain
Human Body Form, Function, and Pathophysiology
Evidence to produce
Vocabulary task
Lab / skill
MedlinePlus: Immune System and Disorders
Quick glossary
CER:
Claim, Evidence, Reasoning — make a claim, back it with evidence, explain your reasoning.
SOP:
Standard Operating Procedure — the exact steps to follow (especially in a lab).
Tracker:
Your PLTW progress log where you record completed evidence.
myPLTW:
The PLTW course site where you do the online activities — you open it through Schoology.
Learn first

Minute-by-minute · 80-minute block

💡 Big idea: The immune system has two layers: a rapid, non-specific innate response and a slower, highly specific adaptive response that creates lasting memory.

  1. 0-10Warm-up: what happens in the first 4 hours after a pathogen enters the body?
  2. 10-28Guided notes: innate barriers, phagocytosis, inflammation vs. adaptive lymphocyte response
  3. 28-45PLTW online immune-response activity
  4. 45-58Map lymphatic system on body diagram; label key nodes and vessels
  5. 58-70Write one question about immune memory; pair-answer
  6. 70-80Submit diagram and PLTW completion confirmation
Mr. Mendoza's 5-minute intro
  • Your body fights infections on two timescales: an immediate general alarm and a slower targeted strike.
  • Today you will map both layers and understand how they connect to vaccine protection.
  • Antigen, antibody, and lymphocyte are core vocabulary for the Microbiology WebXam domain.
  • Leave with a lymphatic system diagram and a clear distinction between innate and adaptive.
Do this, step by step
  1. 1Take notes on innate barriers and adaptive responses.
  2. 2Define antigen, antibody, and lymphocyte.
  3. 3Complete the PLTW online immune-response activity.
  4. 4Map the lymphatic system on a body diagram.
  5. 5Write one question about immune memory.
You'll be able to
  • Innate and adaptive responses are correctly distinguished.
  • PLTW online task is submitted complete.
Know by the end
  • Innate immunity includes physical barriers (skin, mucus) and non-specific cellular responses (phagocytosis, inflammation).
  • Adaptive immunity involves lymphocytes (B and T cells) that recognize specific antigens and create memory for faster future responses.
  • Antibodies are Y-shaped proteins produced by B cells that bind specific antigens to neutralize or tag pathogens.
📺 Tutor me: Khan Academy: The immune system
Do the work

Your PLTW work today

Open this PLTW section today

Unit 3.2 Body Guards: Skin/accessory organs, lymphatic and immune systems, pathogens, immune cells, antigen response. · Innate and adaptive immunity

Day 2 of this lesson. Open this exact section in myPLTW (reached through Schoology), then do the work below.

Do this: Complete the innate-and-adaptive immunity task in Lesson 3.2 Body Guards on myPLTW; work through all screens on phagocytes, B cells, T cells, and antibodies.

Complete

Mark the immunity task complete in myPLTW after submitting your immunity-comparison chart.

How far to get

Monday's task is done; today the immunity task should show complete.

Upload as evidence

Screenshot or note of completion status for your tracker.

All PLTW activities are completed inside the PLTW course environment — this page only gives direction. Submit producibles on Schoology.

The plan

Today's PLTW tracker

Check things off as you work, then submit. This tells Mr. Mendoza how you're doing so he can help the class. It does not replace turning in your producible on Schoology.

Use the code Mr. Mendoza gave you, not your name. Saved on this device.

Unit 3.2 Body Guards: Skin/accessory organs, lymphatic and immune systems, pathogens, immune cells, antigen response.Day 2 of this projectSee the full week plan
Today's PLTW target

Unit 3.2 Body Guards: Skin/accessory organs, lymphatic and immune systems, pathogens, immune cells, antigen response. · Innate and adaptive immunity

Complete the innate-and-adaptive immunity task in Lesson 3.2 Body Guards on myPLTW; work through all screens on phagocytes, B cells, T cells, and antibodies.

Monday's task is done; today the immunity task should show complete.

This is how Mr. Mendoza sees the class keeping pace with PLTW. Be honest, it only helps if it is accurate.

1 · What you do today

🎯 Students will distinguish innate from adaptive immunity using teacher notes and the PLTW online task.

  • Take notes on innate barriers and adaptive responses.
  • Define antigen, antibody, and lymphocyte.
  • Complete the PLTW online immune-response activity.
  • Map the lymphatic system on a body diagram.
  • Write one question about immune memory.
2 · Turn in today

Vocabulary task: Lymphatic system body diagram with key nodes and vessels labeled, plus written definitions of antigen, antibody, and lymphocyte in your own words.

Submit on Schoology

Upload by 11:29 PM for full credit.

3 · Who's doing what (team)
TaskWho
Take notes on innate barriers and adaptive responses._______
Define antigen, antibody, and lymphocyte._______
Complete the PLTW online immune-response activity._______
Map the lymphatic system on a body diagram._______
Write one question about immune memory._______

Working solo? Put your own name in "Who" for every row.

4 · Words I can use correctly
5 · I'm successful today when I can…
  • Innate and adaptive responses are correctly distinguished.
  • PLTW online task is submitted complete.
6 · Reflection & next steps
Where are you today?0/7 checked
Pick your period and code first.
Lab day

Lab & supplies

Bring / set up
Immune-system modeling kit or labeled cutoutsAntigen and antibody shape cardsSkin and lymphatic system diagramsColored markersChart paperLab notebook
MedlinePlus: Immune System and Disorders
Words

This unit's vocabulary

skinlymphantibody/AN-tih-bod-ee/antigen/AN-tih-jen/pathogen/PATH-uh-jen/vaccineinnateadaptive

Tap the speaker to hear a term. Weekly vocabulary task: add two of these terms to your notebook glossary with a definition and an example in your own words.

Check yourself

WebXam practice

Tap an answer to check it · nothing is recorded or graded
Which statement best describes innate immunity compared with adaptive immunity?
An antibody is a protein that:
The lymphatic system contributes to immunity primarily by:
A vaccine protects against disease by:
Check yourself

Cumulative WebXam review

A quick mixed-review pulling questions from earlier units plus today, so the WebXam material stays fresh.

Tap an answer to check it · nothing is recorded or graded
[Review: Challenge Accepted: a model-organism investigation into heavy metals] Identifying the limitations of an experiment is important because it:
[Review: Cardiopulmonary Connection: heart structure and reading an EKG] Blood pressure is typically reported as two numbers representing:
[Review: Gas Exchange: lung volumes, spirometry, and expedition clearance] A pulse oximeter placed on a fingertip measures:
Which statement best describes innate immunity compared with adaptive immunity?
Explore

Where this leads — careers

Safety net

What to do if you were absent

If YOU are absent

Today is individual PLTW work, so do exactly what we did in class, from home: complete the same PLTW target above, then submit your Vocabulary task.

Open Schoology (CMSD) and keep going

How to get there: open the CMSD website, click Clever, sign in with your Microsoft (district) account, then open Schoology from Clever.

If MR. MENDOZA is absent

Class still runs. Complete the online activity above (it's self-guided). Need the concept taught without a teacher? Use this authoritative explainer:

MedlinePlus: Immune System and Disorders
Explore

Optional extra credit (async)

You've passed Unit 2, so the optional extra-credit track is open. Complete reserved-unit work from home (virtual labs included) for extra credit, all submitted on Schoology.

Open the extra-credit track
How this is graded
For: Vocabulary task — Lymphatic system body diagram with key nodes and vessels labeled, plus written definitions of antigen, antibody, and lymphocyte in your own words.
  • Complete
    Every required part of the artifact is present, nothing left blank.
  • Accurate
    The science and the data are correct and match the evidence.
  • Scientific reasoning
    You explain your claim with evidence and reasoning (CER), not just an answer.
  • Professional communication
    Clear, organized, labeled, and written the way a clinician or scientist would.
  • Submitted
    Turned in the right way (Schoology for routine work) and confirmed.
Submission Zone

Drop your Fri, Dec 4, 2026 · Innate and adaptive immunity here. Use a clear file name (your initials + project). Routine work still goes to Schoology (via the CMSD portal).

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